Results 71 to 80 of about 6,795,603 (372)

General Medicine and Hospital Medicine: The Janus of Internal Medicine [PDF]

open access: yesJournal of General Internal Medicine, 2017
In this issue of JGIM, Miller and colleagues draw attention to important trends in the evolution of academic general internal medicine.1 By examining the membership of the Society of General Internal Medicine (SGIM), they provide a snapshot not only of the Society, but also the trajectory of academic internal medicine.
Vineet Chopra, Laurence F. McMahon
openaire   +3 more sources

Cellular liquid biopsy provides unique chances for disease monitoring, preclinical model generation and therapy adjustment in rare salivary gland cancer patients

open access: yesMolecular Oncology, EarlyView.
We quantified and cultured circulating tumor cells (CTCs) of 62 patients with various cancer types and generated CTC‐derived tumoroid models from two salivary gland cancer patients. Cellular liquid biopsy‐derived information enabled molecular genetic assessment of systemic disease heterogeneity and functional testing for therapy selection in both ...
Nataša Stojanović Gužvić   +31 more
wiley   +1 more source

Clinical judgement, expertise and skilled coping [PDF]

open access: yes, 2010
Medicine involves specific practical expertise as well as more general context-independent medical knowledge. This raises the question, what is the nature of the expertise involved?
Aristotle   +17 more
core   +1 more source

Targeting rapid TKI‐induced AXL upregulation overcomes adaptive ERK reactivation and exerts antileukemic effects in FLT3/ITD acute myeloid leukemia

open access: yesMolecular Oncology, EarlyView.
Adaptive ERK reactivation hinders FLT3 tyrosine kinase inhibitor (TKI) treatment in FLT3/ITD acute myeloid leukemia. Here, we report that FLT3 TKI treatment rapidly induces AXL expression and upregulation that is temporally associated with the adaptive ERK reactivation.
Tessa S. Seale   +9 more
wiley   +1 more source

EVIDENCE-BASED MEDICINE – I. GENERAL PRINCIPLES

open access: yesZdravniški Vestnik, 2003
Background. Evidence-based medicine is a method that helps physicians find and critically evaluate evidences from the medical literature, and apply the evidences in clinical decision-making. In clinical practice the method supplements core medical skills,
Angela Čuk
doaj  

Why Compulsory Family Medicine for General Practice?

open access: yesSouth African Family Practice, 2003
No abstract available.
Jannie Hugo
doaj   +1 more source

"It isn't just consultants that need a BSc": student experiences of an Intercalated BSc [PDF]

open access: yes, 2005
More medical schools are moving towards a compulsory intercalated BSc. These courses have not traditionally been aimed at those students interested in general practice and have tended to have limited clinical relevance.
Jones, M., Lloyd, M., Singh, S.
core  

Circulating tumor DNA (ctDNA) trajectories predict survival in trifluridine/tipiracil‐treated metastatic colorectal cancer patients

open access: yesMolecular Oncology, EarlyView.
The authors applied joint/mixed models that predict mortality of trifluridine/tipiracil‐treated metastatic colorectal cancer patients based on circulating tumor DNA (ctDNA) trajectories. Patients at high risk of death could be spared aggressive therapy with the prospect of a higher quality of life in their remaining lifetime, whereas patients with a ...
Matthias Unseld   +7 more
wiley   +1 more source

Message from the Dean and the Chairman of Dental Surgery [PDF]

open access: yes, 2004
The first course of Dental Surgery at the (Royal) University of Malta commenced in October of 1933 in the Faculty of Medicine and Surgery. Recognition of the Diploma in Dental Surgery by the General Medical Council of the UK was granted in 1936, a year ...
Azzopardi, Alexander, Portelli, John M.
core  

Integrative analysis of circulating tumor cells (CTCs) and exosomes from small‐cell lung cancer (SCLC) patients: a comprehensive approach

open access: yesMolecular Oncology, EarlyView.
This study simultaneously investigated circulating tumor cells (CTCs) and exosomes from small‐cell lung cancer (SCLC) patients. The elevated expression of JUNB and CXCR4 in CTCs was a poor prognostic factor for SCLC patients, whereas exosomal overexpression of these biomarkers revealed a high discrimination ability of patients from healthy individuals,
Dimitrios Papakonstantinou   +13 more
wiley   +1 more source

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