Results 121 to 130 of about 1,145,184 (256)

Ketogenic Diet as an Epigenetic Therapy in SETD1B‐Related Epilepsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Histone lysine methyltransferases such as SETD1B regulate chromatin structure and gene transcription. Ketone bodies, including butyrate, act as histone deacetylase inhibitors. We report a 4‐year‐old boy with SETD1B‐related absence epilepsy, refractory to conventional medications, who achieved sustained > 90% seizure reduction on the Modified ...
Erica Tsang, Brian S. Gloss, Jessica P. Hayes, Andrew J. A. Holland, Manoj P. Menezes, Joceline A. Branson, Shekeeb S. Mohammad, Jingya J. Yan, Shrujna Patel, Velda X. Han, Russell C. Dale   +10 more
wiley   +1 more source

Innate Immune Reprogramming Mediated by Endogenous Retroelement Dysregulation Drives Multiple Sclerosis Progression

Annals of Clinical and Translational Neurology, EarlyView.
Epigenetic reprogramming in hematopoietic stem and progenitor cells (HSPCs) and downstream myeloid cells, mediated by H3.3 downregulation and endogenous retroelement (ERE) overexpression, contributes to the progression of multiple sclerosis (MS). ABSTRACT Background Skewed myelopoiesis in the bone marrow has been identified as a key driver of multiple ...
Li‐Mei Xiao, Qiu‐Ping Zhao, Run‐Yun Li, Wei Chen, Huan‐Huan Song, Wan‐Jin Chen, Ying Fu   +6 more
wiley   +1 more source

Synthetic and semi-synthetic antioxidants in medicine and food industry: a review. [PDF]

Front Pharmacol
Tauchen J, Huml L, Jurášek M, Regenstein JM, Ozogul F.   +4 more
europepmc   +1 more source

Preferences for post‐traumatic osteoarthritis prevention strategies in individuals with anterior cruciate ligament injury

Arthritis Care &Research, Accepted Article.
Objectives There is growing interest in evaluating new strategies to delay or prevent post‐traumatic osteoarthritis (PTOA) in individuals who have sustained anterior cruciate ligament (ACL) injury. This study sought to determine characteristics of potential treatments that are acceptable to patients with ACL injury.
Kevin Kennedy, Lily Waddell, Adam Easterbrook, Jeffrey N. Katz, Cale Jacobs, Morgan Jones, Faith Selzer, Elena Losina, Liana Fraenkel, Nick Bansback   +9 more
wiley   +1 more source

Antitumor components and mechanisms of <i>Zanthoxylum bungeanum</i> Maxim with medicine and food homology. [PDF]

Front Pharmacol
Du Y, Duan S, Yang Y, Tibenda JJ, Huang S, Nan Y, Zhang Z, Yuan L.   +7 more
europepmc   +1 more source

Clinical Outcomes of Patients Within the Rheumatoid Arthritis Care Pathway Cohort at a Tertiary Care Integrated Delivery Network: A Comparison to Usual Care

Arthritis Care &Research, EarlyView.
Objective We aimed to compare clinical outcomes between patients in the Allegheny Health Network rheumatoid arthritis (RA) care pathway and patients receiving usual care. Methods The care pathway initiative implements guideline‐based best practice alongside multidisciplinary team‐based care.
Tarun Sharma, Tyson S. Barrett, Teigan Dwyer, Nancy Campbell, Jessica Heintzinger, Ellen Kraemer, Adam Dore, Susan Manzi   +7 more
wiley   +1 more source

What, how, and why? - anti-EHEC phages and their application potential in medicine and food industry. [PDF]

J Appl Genet
Necel A, Dydecka A, Topka-Bielecka G, Wesołowski W, Lewandowska N, Bloch S, Nejman-Faleńczyk B.   +6 more
europepmc   +1 more source

Impact of Positive Lifestyle Behaviors on Direct Health Care Cost Savings for Low Back Pain

Arthritis Care &Research, EarlyView.
Objective This study aimed to investigate the relationship between a previously purpose‐developed lifestyle behavior scale and health care cost savings related to low back pain (LBP). Methods This longitudinal study used data from the Australian Twin Back (AUTBACK) study. LBP and lifestyle behavior measures were collected at baseline. Physical activity
Ye Tian, Katharine E. Roberts, Michelle Hall, Paula R. Beckenkamp, Angelo Sabag, Karoline Moe, Ana Paula Carvalho‐e‐Silva, Emily J. Callander, Paulo H. Ferreira   +8 more
wiley   +1 more source

Assessment of Food Cravings, Food Intake, and Weight Status Among Saudi Adults in Central and Western Regions of Saudi Arabia: A Retrospective, Cross-Sectional Study

Nutrition and Dietary Supplements
Mohammed Zaid Aljulifi,1 Atheer Ayed M Alshutayli,2 Ahmed Mohammed A Kaseb,3 Faisal Mohammed Asiri,4 Renad Ibrahim Alzahrani,5 Nawaf Amer H Alharbi,5 Ghadeer Yahya Almasabi,5 Mudhawi Faisal Alsuliman,6 Mohammad Shakil Ahmad,1 Riyaz Ahmed Shaik1 ...
Aljulifi MZ, Alshutayli AAM, Kaseb AMA, Asiri FM, Alzahrani RI, Alharbi NAH, Almasabi GY, Alsuliman MF, Ahmad MS, Shaik RA   +9 more
doaj  

Research progress on the effect of medicine and food homology resources for sleep improvement. [PDF]

Heliyon
Ma J, Huang S, Shi L, Shen Y, Gao S, Wu Z.   +5 more
europepmc   +1 more source