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Applications of Medium-Chain Triglycerides in Foods. [PDF]

open access: yesFront Nutr, 2022
In the 1950s, the production of processed fats and oils from coconut oil was popular in the United States. It became necessary to find uses for the medium-chain fatty acids (MCFAs) that were byproducts of the process, and a production method for medium ...
Watanabe S, Tsujino S.
europepmc   +2 more sources

Dietary medium chain triglycerides impairs orexigenic action of ghrelin in mice. [PDF]

open access: yesFront Endocrinol (Lausanne)
IntroductionGhrelin, a stomach-derived hormone, increases food intake and body weight. Efforts have been made therefore to modulate ghrelin signaling for the treatment of obesity or emaciation.
Aotani D   +12 more
europepmc   +2 more sources

Feeding of fish oil and medium-chain triglycerides to canines impacts circulating structural and energetic lipids, endocannabinoids, and non-lipid metabolite profiles. [PDF]

open access: yesFront Vet Sci, 2023
IntroductionThe effect of medium-chain fatty acid-containing triglycerides (MCT), long-chain polyunsaturated fatty acid-containing triglycerides from fish oil (FO), and their combination (FO+MCT) on the serum metabolome of dogs (Canis familiaris) was ...
Jackson MI, Jewell DE.
europepmc   +2 more sources

Effects of medium chain triglycerides on hepatic fatty acid oxidation in clofibrate-fed newborn piglets. [PDF]

open access: yesAnim Nutr, 2023
To investigate whether increasing tricarboxylic acid (TCA) cycle activity and ketogenic capacity would augment fatty acid (FA) oxidation induced by the peroxisome proliferator-activated receptor-alpha (PPARα) agonist clofibrate, suckling newborn piglets (
Zhao J   +5 more
europepmc   +2 more sources

Supplementation of Regular Diet With Medium-Chain Triglycerides for Procognitive Effects: A Narrative Review. [PDF]

open access: yesFront Nutr, 2022
It is now widely accepted that ketosis (a physiological state characterized by elevated plasma ketone body levels) possesses a wide range of neuroprotective effects.
Shcherbakova K   +4 more
europepmc   +2 more sources

Effect of medium-chain triglycerides supplements and walking on health-related quality of life in sedentary, healthy middle-aged, and older adults with low BMIs: a randomized, double-blind, placebo-controlled, parallel-group trial. [PDF]

open access: yesFront Nutr, 2023
IntroductionTo extend individuals’ healthy life expectancies, the improvement of subjective health and quality of life (QOL) has been increasingly prioritized, alongside the improvement of their physical functioning. Reports have indicated that intake of
Ishikawa H   +4 more
europepmc   +2 more sources

Medium Chain Triglycerides Modulate the Ketogenic Effect of a Metabolic Switch. [PDF]

open access: yesFront Nutr, 2020
Ketones provide an alternative brain fuel and may be neuroprotective in older people. Little is known of how to optimize the ketogenic effect of C8:0–C10:0 medium chain triglyceride supplement (kMCT). Metabolic switching (MS) from glucose to ketones as a
Vandenberghe C   +5 more
europepmc   +2 more sources

Medium-chain triglycerides inhibit long-chain triglyceride-induced GIP secretion through GPR120-dependent inhibition of CCK. [PDF]

open access: yesiScience, 2021
Summary: Long-chain triglycerides (LCTs) intake strongly stimulates GIP secretion from enteroendocrine K cells and induces obesity and insulin resistance partly due to GIP hypersecretion.
Murata Y   +13 more
europepmc   +2 more sources

Effect of Different Medium-Chain Triglycerides on Glucose Metabolism in High-Fat-Diet Induced Obese Rats. [PDF]

open access: yesFoods
Obesity can be associated with significant metabolic disorders. Our previous study found that medium-chain triglycerides (MCTs) improved lipid metabolism in obese rats.
Xia J   +7 more
europepmc   +2 more sources

A high-fat diet supplemented with medium-chain triglycerides ameliorates hepatic steatosis by reducing ceramide and diacylglycerol accumulation in mice. [PDF]

open access: yesExp Physiol
Non‐alcoholic fatty liver disease (NAFLD) is projected to be the most common chronic liver disease worldwide and is closely linked to obesity, insulin resistance and type 2 diabetes.
Mourad S   +5 more
europepmc   +2 more sources

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