Results 191 to 200 of about 117,843 (251)

Engineered Peptide Self‐Assembled Nanofibers for Enhanced STING Activation: A Promising Nanodelivery Platform for Immunotherapy of Pediatric Solid Tumors

Advanced Science, EarlyView.
An engineered peptide self‐assembled nanofiber platform, designed to replicate STING–cGAMP binding motifs, facilitates pH‐responsive cytosolic delivery of cGAMP, enhances the endoplasmic reticulum with high efficiency, and robustly activates the STING pathway.
Yubin He, Xiao Lu, Chang qing Yang, Ran Zhang, Bo Wan, Xin Ni, Dong Mei   +6 more
wiley   +1 more source

Enhanced In Vivo Antinociceptive Activity and GC-MS Chemical Profiling of In Vitro-Grown <i>Acmella radicans</i> Plants Elicited with <i>Rhizopus microsporus</i>. [PDF]

Molecules
Hernández-Aubert G, Montiel-Ruiz RM, Hurtado-Díaz I, Silva-Guzmán JA, Torres-Rendón JG, Manríquez-González R, Cruz-Sosa F, Bernabé-Antonio A.   +7 more
europepmc   +1 more source

Transfer RNA‐Derived Small RNA‐5’tiRNAGln Drives HNRNPC Phase Separation to Promote Breast Cancer Bone Metastasis by Regulating IGF1R

Advanced Science, EarlyView.
This study reveals that 5'tiRNA‐Gln interacts with hnRNPC to promote IGF1R liquid‐liquid phase separation, which drives ERK1/2 signaling activation, EMT, and breast cancer bone metastasis. These findings highlight a novel mechanism of breast cancer bone metastasis and potential therapeutic target in metastatic breast cancer.
Bingnan Wang, Dongsong Liu, Xiaozhi Fan, Jiale Fan, Xuesi liu, Yu Wang, Zixin Wang, Mo Cheng, Ping Zhou, Wangjun Yan   +9 more
wiley   +1 more source

Distinct polyamine effects on <i>Candida albicans</i> morphogenesis identify spermidine as a key regulator. [PDF]

Microbiol Spectr
Pathirana RU, Camargo MI, Vela GG, Kadosh D.   +3 more
europepmc   +1 more source

Spray-Based Triboelectric Nanogenerator With Ultra-High Current for Hydrogen Generation. [PDF]

Adv Mater
Cheng J, Dong Y, Zhang L, Feng Y, Wang W, Zhang X, Li W, Meng J, Lu W, Wang D.   +9 more
europepmc   +1 more source

Can low-thickness, low-value mixed plastic waste be converted into petrochemical fuels on a large scale? [PDF]

RSC Adv
Chintala V, Shaiwale M, Makwana S, Mishra RK.   +3 more
europepmc   +1 more source

Covalent Targeting and Thermostabilization of Oncogenic R280K and R273H Mutants p53 by Small Molecule RVJB59. [PDF]

ChemMedChem
Ferreira RJF, Gonçalves LM, Mori M, Antunes AMM, Leandro AP, Santos MMM.   +5 more
europepmc   +1 more source