Results 41 to 50 of about 168,832 (301)

Coiling simulations of medium-Mn sheet steels using dilatometry

IOP Conference Series: Materials Science and Engineering, 2020
Abstract The work presents the results of coiling simulations of two medium manganese steels containing 3 and 5% Mn. The steels were subjected to the heat treatment including an austenitization at 1000°C for 300s and next isothermal holding at temperatures of 750, 700, 650 and 500°C for duration of 5 hours.
M. Morawiec, A. Skowronek, W. Pakieła, A. Grajcar   +3 more
openaire   +1 more source

Effect of laser-welding parameters on the heat input and weld-bead profile [PDF]

, 2005
Laser butt-welding of medium carbon steel was investigated using CW 1.5 kW CO2 laser. The effect of laser power (1.2 - 1.43 kW), welding speed (30 - 70 cm/min) and focal point position (-2.5 - 0 mm) on the heat input and the weld-bead geometry (i.e ...
A.G. Olabi, Allen, Benyounis, Dawes, Fuerschbach, Gunaraj, Gunaraj, Huang, K.Y. Benyounis, Khuri, Kim, M.S.J. Hashmi, Montgomery, Steen   +13 more
core   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Influence of boron content on the fracture toughness and fatigue crack propagation kinetics of bainitic steels [PDF]

, 2016
The relatively good combination of high strength and ductility makes bainitic steels a candidate to replace many other steels in industrial applications. However, in service, ductility and strength are not up to standard requirements.
Cabrera Marrero, José M., Mestra Rodríguez, Álvaro Miguel, Olaya Florez, Jhon Jairo, Rodriguez Galeano, Karol-Felipe, Rodríguez Baracaldo, Rodolfo   +4 more
core   +2 more sources

Insights Into the Antigenic Repertoire of Unclassified Synaptic Antibodies

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective We sought to characterize the sixth most common finding in our neuroimmunological laboratory practice (tissue assay‐observed unclassified neural antibodies [UNAs]), combining protein microarray and phage immunoprecipitation sequencing (PhIP‐Seq). Methods Patient specimens (258; 133 serums; 125 CSF) meeting UNA criteria were profiled;
Michael Gilligan, John R. Mills, Paulina Vargas, Naveen K. Paramasivan, Connie E. Lesnick, Eati Basal, Surendra Dasari, James P. Fryer, Shannon R. Hinson, Joseph Laporta, Amy Espinal, Dennis Fitzgerald, Carolina Garcia, Anna E. Morenkova, Paola Pergami, Anna Shah, Andrew Knight, Reghann LaFrance Corey, Vanda A. Lennon, Anastasia Zekeridou, Sean J. Pittock, Divyanshu Dubey, Andrew McKeon   +22 more
wiley   +1 more source

Effects of different intercritical annealing processes on microstructure and cryogenic toughness of newly designed medium-Mn and low-Ni steel

Journal of Materials Research and Technology, 2023
Through the idea of replacing Ni with Mn, a shortened process of ultra-fast cooling and two-step intercritical annealing for medium-Mn and low-Ni steel after rolling was designed.
Zhihui Liao, Ying Dong, Yu Du, Xiaonan Wang, Min Qi, Hongyan Wu, Xiuhua Gao, Linxiu Du   +7 more
doaj   +1 more source

TBK1‐Associated Primary Lateral Sclerosis Followed by Right Temporal Variant Frontotemporal Dementia

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT We report a 58‐year‐old woman with a novel splice‐site variant in the TANK‐binding kinase 1 (TBK1:c.993–2A>C p.Ala332TyrfsTer39) who sequentially developed primary lateral sclerosis (PLS) followed by right temporal variant frontotemporal dementia (rtvFTD). Neuroimaging demonstrated right anterior temporal atrophy before cognitive symptoms, and
Tomoyasu Matsubara, Naoki Kihara, Satoko Miyatake, Koji Fujita, Konoka Tachibana, Ryosuke Miyamoto, Hiroki Yamazaki, Yusuke Osaki, Nazere Keyoumu, Yuki Kuwano, Nobutoshi Morimoto, Suzuran Saito, Eriko Koshimizu, Yoichi Otomi, Kenji Ishibashi, Masafumi Harada, Naomichi Matsumoto, Hiroyuki Morino, Yuishin Izumi   +18 more
wiley   +1 more source

Effects of mechanical and chemical heterogeneity on the strength-ductility synergy of a heterostructured medium Mn steel

Journal of Materials Research and Technology
A medium Mn steel with both mechanical and chemical heterogeneities is designed in this study, demonstrating an excellent combination of high strength and ductility.
Yuming Zou, Haokun Zhu, Qihan Gao, Kaichao Xie, Jialin Chen, Hua Ding, Zhengyou Tang, Zhouhua Jiang   +7 more
doaj   +1 more source

Local analysis of oxygen reduction catalysis by scanning vibrating electrode technique : a new approach to the study of biocorrosion [PDF]

, 2008
The scanning vibrating electrode technique (SVET)was employed to investigate oxygen reduction catalysis by the presence of enzyme in an aerobic medium.
Basséguy, Régine, Bergel, Alain, Etcheverry, Luc, Iken, Hicham   +3 more
core   +1 more source