Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
He Ara Angitu: A Description of Literacy Achievement for Year 0 - 2 students in Total Immersion in Māori Programmes [PDF]
In response to the recommendations of the Literacy Taskforce Report (1999) and issues highlighted in the Green Paper - Assessment for Success in Primary Schools (1998), the Ministry of Education funded a project in 2000 and 2001 to develop a description ...
Glynn, Ted +4 more
core +1 more source
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
Eksperimentasi Model Pembelajaran Kooperatif Tipe Jigsaw Dan Group Investigation (Gi) Pada Pembelajaran Dimensi Tiga Siswa Kelas X SMA Negeri Se-kabupaten Wonogiri Ditinjau Dari Tingkat Kecerdasan Emosional Tahun Pelajaran 2012/2013 [PDF]
The objectives of this research were to investigate: (1) which one providing better learning achievement, the Jigsaw learning model, GI or direct instruction; 2) which one having better learning achievement, the students with high, medium or low ...
Riyadi, R. (Riyadi) +2 more
core
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
Language of instruction, both in schools and higher education institutions (HEIs), is a contentious issue in South Africa. At our university in the KwaZulu-Natal province of South Africa a language policy was approved in agreement with the Language ...
Linda van Laren, Busisiwe Goba
doaj +1 more source
Support for Instructional Leadership: Supervision, Mentoring, and Professional Development for U.S. School Leaders - Findings from the American School Leader Panel [PDF]
With school leadership second only to teaching among school-related influences on student learning, principals can play an important role in school success. But how do their districts promote their effectiveness, especially in improving teaching?
Julia H. Kaufman +2 more
core
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
PENGARUH EFEKTIVITAS PENGGUNAAN MEDIA PEMBELAJARAN TERHADAP HASIL BELAJAR KETERAMPILAN MENGETIK MAHASISWA PENDIDIKAN MANAJEMEN PERKANTORAN UNIVERSITAS PENDIDIKAN INDONESIA [PDF]
Penelitian ini dilatarbelakangi dari keterampilan mengetik mahasiswa yang belum mencapai nilai yang baik. Salah satu faktor yang mempengaruhi hasil belajar mahasiswa dalam mengetik adalah efektifitas penggunaan media pembelajaran.
Lestari, Hanisa Sismaya
core
ESP, EMI and interculturality: How internationalised are university curricula in Catalonia? [PDF]
This study analyses Internationalisation at Home (IaH) courses across a wide range of bachelor’s degrees, from humanities to hard sciences, in public universities in Catalonia, as an in-depth analysis of a South European context. IaH courses selected for
Aguilar Pérez, Marta +1 more
core +2 more sources

