Results 61 to 70 of about 173,378,546 (253)

DNA ligase LigE increases bacterial transformation with damaged extracellular DNA

FEBS Letters, EarlyView.
The DNA ligase LigE from the naturally competent Gram‐negative bacterium Neisseria gonorrhoaea increases transformation with cut extracellular DNA. This process is ATP‐dependent and relies on the catalytic activity of LigE; it also requires that LigE contains an intact periplasmic localisation sequence, indicating that ligE functions in the periplasm ...
Jolyn Pan, Avi Singh, Shrawani Weralupe Gamladdalage, Joanna Hicks, Adele Williamson   +4 more
wiley   +1 more source

Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy

FEBS Letters, EarlyView.
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley   +1 more source

Internationalizing education through English medium instruction : organizational learning, innovation leadership and teacher-researchers

, 2013
This chapter addresses several interrelated concerns that bedevil reforms intended to internationalize education via English Medium Instruction, specifically the work of management and leadership in structuring university learning for change.
Singh, Michael (R10515)
core  

Language choice in Saudi medical education: stakeholder perspectives on avoiding Arabic as the medium of instruction

Frontiers in Education
IntroductionEnglish-medium instruction remains dominant in Saudi medical education despite growing recognition that Arabic, the official language, can support comprehension, participation, and clinical communication.
Khatmah Alanazi
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Internationalizing Education Through English Medium Instruction: Key Theoretic-Pedagogical Ideas

, 2014
With growing internationalization of higher education around the world, teaching in English Medium Instruction (EMI), as an important component in content and language integrated learning (CLIL), is becoming a dominant pedagogy in those countries who ...
Singh, Michael (R10515), Han, Jinghe (R16321)   +1 more
core  

“Your brother is compelled–not a hero!”

L’Année du Maghreb
Despite the “perpetual” implementation of the Arabisation policy in Algeria, French remains the de facto medium of instruction (MOI) in scientific courses in Algerian universities. The complex nature of MOI policy in Algeria calls for the need to explore
Imene Medfouni
doaj   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Language of Instruction Policy in Science Programs: Science University Students’ Voices

Jurnal Pendidikan IPA Indonesia, 2019
The language of instruction policy in science university programs is chosen by different stakeholders. The voice of science university students (SUSs) has been neglected in many science programs around the world.
M. Alhamami
doaj   +1 more source

The effect of limited sign language as barrier to teaching and learning among Deaf learners in South Africa

South African Journal of Education, 2020
In the study reported on here we investigated the effects of sign language barriers among Deaf learners in special schools for the Deaf and Blind in the Motheo District in the Free State province of South Africa.
Winnie Poelane Ngobeni, Joseph Ramathibela Maimane, Mmushetji Petrus Rankhumise   +2 more
doaj   +1 more source