Results 61 to 70 of about 732,819 (307)

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

He Ara Angitu: A Description of Literacy Achievement for Year 0 - 2 students in Total Immersion in Māori Programmes [PDF]

open access: yes, 2001
In response to the recommendations of the Literacy Taskforce Report (1999) and issues highlighted in the Green Paper - Assessment for Success in Primary Schools (1998), the Ministry of Education funded a project in 2000 and 2001 to develop a description ...
Glynn, Ted   +4 more
core   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

open access: yesFEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa   +3 more
wiley   +1 more source

Eksperimentasi Model Pembelajaran Kooperatif Tipe Jigsaw Dan Group Investigation (Gi) Pada Pembelajaran Dimensi Tiga Siswa Kelas X SMA Negeri Se-kabupaten Wonogiri Ditinjau Dari Tingkat Kecerdasan Emosional Tahun Pelajaran 2012/2013 [PDF]

open access: yes, 2014
The objectives of this research were to investigate: (1) which one providing better learning achievement, the Jigsaw learning model, GI or direct instruction; 2) which one having better learning achievement, the students with high, medium or low ...
Riyadi, R. (Riyadi)   +2 more
core  

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

open access: yesFEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga   +3 more
wiley   +1 more source

‘They say we are crèche teachers’: Experiences of pre-service mathematics teachers taught through the medium of isiZulu

open access: yesPythagoras, 2013
Language of instruction, both in schools and higher education institutions (HEIs), is a contentious issue in South Africa. At our university in the KwaZulu-Natal province of South Africa a language policy was approved in agreement with the Language ...
Linda van Laren, Busisiwe Goba
doaj   +1 more source

Support for Instructional Leadership: Supervision, Mentoring, and Professional Development for U.S. School Leaders - Findings from the American School Leader Panel [PDF]

open access: yes, 2016
With school leadership second only to teaching among school-related influences on student learning, principals can play an important role in school success. But how do their districts promote their effectiveness, especially in improving teaching?
Julia H. Kaufman   +2 more
core  

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

PENGARUH EFEKTIVITAS PENGGUNAAN MEDIA PEMBELAJARAN TERHADAP HASIL BELAJAR KETERAMPILAN MENGETIK MAHASISWA PENDIDIKAN MANAJEMEN PERKANTORAN UNIVERSITAS PENDIDIKAN INDONESIA [PDF]

open access: yes, 2015
Penelitian ini dilatarbelakangi dari keterampilan mengetik mahasiswa yang belum mencapai nilai yang baik. Salah satu faktor yang mempengaruhi hasil belajar mahasiswa dalam mengetik adalah efektifitas penggunaan media pembelajaran.
Lestari, Hanisa Sismaya
core  

ESP, EMI and interculturality: How internationalised are university curricula in Catalonia? [PDF]

open access: yes, 2018
This study analyses Internationalisation at Home (IaH) courses across a wide range of bachelor’s degrees, from humanities to hard sciences, in public universities in Catalonia, as an in-depth analysis of a South European context. IaH courses selected for
Aguilar Pérez, Marta   +1 more
core   +2 more sources

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