Results 101 to 110 of about 701,729 (307)

Producción científica institucional y posicionamiento nacional: el caso del Hospital General de México

open access: yesRevista Española de Documentación Científica, 2004
El propósito de este trabajo fue el de identificar la producción, visibilidad y posicionamiento científico del Hospital General de México (HGM). Para la identificación de la producción del hospital, se condujo una investigación bibliográfica en las ...
C. A. Macías-Chapula   +3 more
doaj   +1 more source

Network Properties Revealed during Multi-Scale Calcium Imaging of Seizure Activity in Zebrafish. [PDF]

open access: yes, 2019
Seizures are characterized by hypersynchronization of neuronal networks. Understanding these networks could provide a critical window for therapeutic control of recurrent seizure activity, i.e., epilepsy.
Baraban, Scott C, Liu, Jing
core   +1 more source

Switching disease‐modifying therapies in patients with spinal muscular atrophy: A systematic review on effectiveness outcomes

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
With multiple disease‐modifying therapies now available, treatment switching has become an important clinical consideration in the management of spinal muscular atrophy (SMA). While some switches are prompted by suboptimal clinical response, more commonly they are driven by treatment burden, convenience, or adverse events.
Andrej Belančić   +4 more
wiley   +1 more source

Estimating the burden of rheumatoid arthritis in Africa:A systematic analysis [PDF]

open access: yes, 2012
Rheumatoid arthritis (RA) has an estimated worldwide prevalence of 1%. It is one of the leading causes of chronic morbidity in the developed world, but little is known about the disease burden in Africa. RA is often seen as a minor health problem and has
Abdel-Nasser   +32 more
core   +3 more sources

Current evidence and insights on single vs. double dose of basiliximab in adult solid organ transplant recipients: A systematic review

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Abstract Aim The aim of this systematic review was to assess all available clinical data regarding the use of a single dose of basiliximab in solid organ transplantation compared to the standard double dosage, with particular interest in efficacy, safety and cost‐savings.
Alessio Provenzani   +4 more
wiley   +1 more source

How to search the medical literature

open access: yesCurrent Medicine Research and Practice, 2011
Searching the medical literature is often difficult and sometimes quite confusing. It is important to know the available databases and search tools along with their strengths and limitations.
Vivek Choudhary   +3 more
doaj  

Younger adolescents’ perceptions of physical activity, exergaming, and virtual reality:qualitative intervention development study [PDF]

open access: yes, 2019
Background. Novel strategies to promote physical activity (PA) in adolescence are required. The vEngage study aims to test whether a virtual reality (VR) exergaming intervention can engage younger adolescents (13-15 year old) with physical activity ...
Farič, Nusa   +8 more
core   +5 more sources

Efficacy, safety and cost‐effectiveness of CAR‐T therapy

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
CAR T‐cells demonstrate high efficacy in blood cancers, including ALL, MM and DLBCL. Innovations target solid tumours despite challenges such as antigen escape. Combination therapies enhance the delivery and infiltration of CAR T cells. Toxicity, cost and resistance remain major barriers to clinical use.
Emina Karahmet Sher   +7 more
wiley   +1 more source

Do drugs approved via expedited approval pathways have therapeutic advantages? A systematic review and meta‐analysis

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Regulators use expedited approval pathways to speed market approval and patient access to promising new drugs. However, there is uncertainty about whether these pathways are successful in approving drugs with significant therapeutic advantages. This systematic review aims to examine the safety, effectiveness and cost‐effectiveness of drugs approved via
Ashleigh Hooimeyer   +4 more
wiley   +1 more source

The evidence-based medicine pico strategy applied to dentistry using Mesh, Emtree and Decs

open access: yesRevista Facultad de Odontología Universidad de Antioquia, 2019
Introduction: the PICO mnemonic is an evidence-based medicine tool that helps formulate the research questions needed to conduct the right search for scientific information.
María Teresa Alarcón-Gil   +2 more
doaj   +1 more source

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