Results 121 to 130 of about 658,046 (339)

UGT1A1 and Sacituzumab Govitecan Toxicity: A Systematic Review and Meta‐Analysis

Clinical Pharmacology &Therapeutics, EarlyView.
Sacituzumab govitecan (SG), a humanized antibody‐drug conjugate, enables intra‐tumor delivery of SN‐38, the active metabolite of irinotecan, with the aim of increasing efficacy. SN‐38 is predominantly inactivated by the polymorphically expressed uridine diphosphate glucuronosyltransferase 1A1 (UGT1AA) where reduced activity can lead to toxicity.
Cinzia Dello Russo, Innocent Gerald Asiimwe, Sudeep Pushpakom, Carlo Palmieri, Munir Pirmohamed   +4 more
wiley   +1 more source

World thyroidology news

Клиническая и экспериментальная тиреоидология, 2014
The article is to overview papers: Effect of vitamin C on the absorption of levothyroxine in patients with hypothyroidism and gastritis. Management of neonates born to women with Graves’ disease: a cohort study.
Yuliya Aleksandrovna Manuylova, Anna Evgenyevna Shvedova   +1 more
doaj   +1 more source

Medical Informatics Special Issue on MEDLINE [PDF]

, 1980
P Laudat
openalex   +1 more source

Emotional abuse of girls in Swaziland: prevalence, perpetrators, risk and protective factors and health outcomes [PDF]

, 2017
Background: Research on emotional child abuse in sub–Saharan Africa is scarce. Few studies thus far have examined prevalence, risk and protective factors for emotional child abuse or the associations between emotional abuse and girls’ health. Methods:
Dunne, Michael P., Elizalde, Aldo, Fry, Deborah, Ginindza, Choice, Maternowska, M. Catherine, Meinck, Franziska, Spreckelsen, Thees F., Wazny, Kerri   +7 more
core   +5 more sources

Identification and Management of Binge‐Eating Disorder and Bulimia Nervosa in Primary Care Settings: A Qualitative Systematic Review of Healthcare Professionals' and Patients' Perceptions

International Journal of Eating Disorders, EarlyView.
ABSTRACT Objective To understand how the identification and management of binge‐eating disorder (BED) and bulimia nervosa (BN) in primary care settings are perceived by both patients and healthcare professionals, and how rates of identification and referral for support may be improved.
Stella Kozmér, Christopher O'Rouke, Natalia S. Lawrence, Jane R. Smith, Samantha B. van Beurden   +4 more
wiley   +1 more source

A systematic review of outcomes reported in randomized controlled trials involving people with patellar dislocations

Bone & Joint Open
Aims: The primary aims were to determine what outcome domains, outcome measurement instruments, and outcome measurement timepoints are reported in randomized controlled trials (RCTs) involving people with patellar dislocations. The secondary aims were to
Colin P. Forde, Crispin Mortimer, Toby O. Smith, Matthew L. Costa, Jonathan A. Cook, Elizabeth Tutton, Georgina Wistow, Paul Minty, David J. Keene   +8 more
doaj   +1 more source

The difficult discussion on the deactivation of implantable cardioverter devices at the end of life: a systematic review

ESC Heart Failure, Volume 12, Issue 2, Page 733-760, April 2025.
Abstract Implantable cardioverter defibrillators (ICDs) reliably prevent death due to life‐threatening arrhythmias; this may become less relevant in people with more severe heart failure who are reaching the end of life (EOL). This review aimed to explore the ICD deactivation process and identify ethical issues, especially around the initiation of ...
Siobhan C. Murray, Claire McNamara, Anna V. Chatzi   +2 more
wiley   +1 more source

MEDLINE. A GUIDE TO EFFECTIVE SEARCHING. [PDF]

, 2000
Dorothy Connell, Katy Gwyther, Lesley Sander, Alison Weightman   +3 more
openalex   +3 more sources

Tracing malformation syndromes with MEDLINE. [PDF]

, 1984
Carolyn Norris
openalex   +1 more source

Sources of Evidence — MEDLINE [PDF]

Evidence-Based Dentistry, 2003
MEDLINE (Medical Literature, Analysis and Retrieval System Online) is the US National Library of Medicine's premier bibliographical database. It concentrates on biomedical sciences and contains over 12 million references to journal articles in life sciences.
openaire   +1 more source