Treatment of symptoms of the menopause: an endocrine society clinical practice guideline [PDF]
Objective: The objective of this document is to generate a practice guideline for the management and treatment of symptoms of the menopause. Participants: The Treatment of Symptoms of the Menopause Task Force included six experts, a methodologist, and
Davis, Susan R. +6 more
core +1 more source
Safety and Acceptability of Community-Based Distribution of Injectable Contraceptives: A Pilot Project in Mozambique. [PDF]
Mozambique has witnessed a climbing total fertility rate in the last 20 years. Nearly one-third of married women have an unmet need for family planning, but the supply of family planning services is not meeting the demand. This study aimed to explore the
Bique, Cassimo +6 more
core +1 more source
Medroxyprogesterone acetate exacerbates glutamate excitotoxicity
We previously demonstrated that progesterone functions as a neuroprotective agent whereas medroxyprogesterone acetate (MPA; Provera) does not. Moreover, MPA antagonized the neuroprotective and neurotrophic outcomes induced by 17beta-estradiol (E2). Towards developing effective hormone therapies for protection against neurodegeneration, we sought to ...
Jon, Nilsen +2 more
openaire +2 more sources
Medroxyprogesterone acetate levels among Kenyan women using depot medroxyprogesterone acetate in the FEM-PrEP trial [PDF]
To describe medroxyprogesterone acetate (MPA) levels among Kenyan depot medroxyprogesterone acetate (DMPA) users in the FEM-PrEP HIV prevention trial, and to compare MPA levels between ARV for HIV prevention (treatment) and placebo groups.We measured MPA in previously collected plasma samples from 63 Kenyan trial participants who used DMPA for one or ...
Nanda, Kavita +7 more
openaire +2 more sources
Immunophenotype of Atypical Polypoid Adenomyoma of the Uterus: Diagnostic Value and Insight on Pathogenesis [PDF]
Atypical polypoid adenomyoma (APA) is a rare uterine lesion constituted by atypical endometrioid glands, squamous morules, and myofibromatous stroma. We aimed to assess the immunophenotype of the 3 components of APA, with regard to its pathogenesis and ...
Aggarwal +46 more
core +1 more source
Depot medroxyprogesterone acetate (DMPA) is a contraceptive method that prevents ovulation and reduces endometrial thickness. This study aimed to investigate the influence of Vigna unguiculata (VU) on estrogen receptor-α expression and endometrial ...
Rizki Fitrianingtyas +5 more
doaj +1 more source
Adolescents’ Acceptance of Long-Acting Reversible Contraception After an Educational Intervention in the Emergency Department: A Randomized Controlled Trial [PDF]
Introduction: Adolescents who seek care in the emergency department (ED) are a cohort at increased risk of unintended pregnancy. Although adolescents are interested in learning about pregnancy prevention in the ED, there is a lack of effective ...
Bachrach, Lela +3 more
core
Medroxyprogesterone improves nocturnal breathing in postmenopausal women with chronic obstructive pulmonary disease [PDF]
Background Progestins as respiratory stimulants in chronic obstructive pulmonary disease (COPD) have been investigated in males and during wakefulness. However, sleep and gender may influence therapeutic responses. We investigated the effects of a 2-week
Aittokallio Tero +3 more
core +2 more sources
Objective: The purpose of this paper is to consolidate existing evidence and identify knowledge and research gaps on the bone health effects of progestin-only oral contraception, injectables, hormonal intrauterine devices, and implants.
Blake Erhardt-Ohren, MPH +2 more
doaj +1 more source
Ovarian function during hormonal contraception assessed by endocrine and sonographic markers: a systematic review [PDF]
This systematic review focuses on the literature evidence for residual ovarian function during treatment with hormonal contraceptives. We reviewed all papers which assessed residual ovarian activity during hormonal contraceptive use, using endocrine ...
Bastianelli, Carlo +5 more
core +1 more source

