Results 41 to 50 of about 13,589 (222)

The relationship between sex hormones, the vaginal microbiome and immunity in HIV-1 susceptibility in women

Disease Models & Mechanisms, 2018
The role of sex hormones in regulating immune responses in the female genital tract has been recognized for decades. More recently, it has become increasingly clear that sex hormones regulate susceptibility to sexually transmitted infections through ...
Jocelyn M. Wessels, Allison M. Felker, Haley A. Dupont, Charu Kaushic   +3 more
doaj   +1 more source

Association of novel intra‐cesarean post‐placental intrauterine device insertion techniques, and early ultrasound, with expulsion rates and strings visibility: A prospective exploratory study

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective To assess an innovative technique of intra‐cesarean post‐placental insertion of the Copper T380A IUD (CPPIUD), and explore the role of predischarge ultrasound with replacement of low‐lying IUDs. Methods We conducted a prospective observational study at Princess Marina Hospital, Gaborone, Botswana, from May 31, 2023, to April 3, 2024.
Kyungu M. Kime, Liza Bazzett‐Matabele, G. Justus Hofmeyr   +2 more
wiley   +1 more source

Effects of medroxyprogesterone acetate on human cytochrome P450 enzymes [PDF]

, 2005
Medroxyprogesterone acetate (MPA), frequently used in contraception and chemotherapy, was reported involving in drug-drug interaction (DDI). However, the mechanism is still unclear.
张江伟, 李巍, 刘勇, 杨凌
core  

Efficacy of Different Progestins in Women With Advanced Endometriosis Undergoing Controlled Ovarian Hyperstimulation for in vitro Fertilization-A Single-Center Non-inferiority Randomized Controlled Trial

Frontiers in Endocrinology, 2020
Object: Is it possible to use different progestins cotreatment with human menopausal gonadotrophin (hMG) in women with advanced endometriosis but normal ovulation during controlled ovarian hyperstimulation (COH) in vitro fertilization (IVF)?
Haiyan Guo, Jianghui Li, Xi Shen, Yanyan Cong, Yun Wang, Ling Wu, Bin Li, Hongyuan Gao, Meng Ma, Wei Zhang, Xiaoyan Mao, Yonglun Fu, Qifeng Lyu, Weiran Chai, Yanping Kuang   +14 more
doaj   +1 more source

Invasiveness of endometrial cancer cell lines is potentiated by estradiol and blocked by a traditional medicine Guizhi Fuling at clinically relevant doses

Frontiers in Oncology, 2023
The Traditional Chinese medicine, Guizhi Fuling (here called Fuling), has been confirmed in meta-analysis studies to reduce recurrence of endometriosis and improve pregnancy outcomes; however, the possible use of Fuling as a fertility-preserving ...
Sidra Khan, Alanah Varricchio, Carmela Ricciardelli, Andrea J. Yool   +3 more
doaj   +1 more source

Preoperative and postoperative pathology concordance in endometrial intraepithelial neoplasia: A retrospective cohort study

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective To assess the concordance between pre‐ and postoperative pathology in patients with endometrial intraepithelial neoplasia (EIN) undergoing hysterectomy, and identify predictors of malignancy, including sampling method, progestin therapy, and surgical timing.
Jenny Dimakos, Dong Bach Nguyen, Xing Zeng, Jessica Papillon Smith, Fady W. Mansour, Srinivasan Krishnamurthy, Andrew Zakhari   +6 more
wiley   +1 more source

Medroxyprogesterone acetate exacerbates glutamate excitotoxicity

Gynecological Endocrinology, 2006
We previously demonstrated that progesterone functions as a neuroprotective agent whereas medroxyprogesterone acetate (MPA; Provera) does not. Moreover, MPA antagonized the neuroprotective and neurotrophic outcomes induced by 17beta-estradiol (E2). Towards developing effective hormone therapies for protection against neurodegeneration, we sought to ...
Jon, Nilsen, Alison, Morales, Roberta Diaz, Brinton   +2 more
openaire   +2 more sources

Efficacy and related factors of levonorgestrel‐releasing intrauterine system combined with metformin in fertility‐preserving treatment for atypical endometrial hyperplasia and early endometrial cancer: A retrospective cohort study

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective To compare the efficacy of the levonorgestrel‐releasing intrauterine system combined with metformin versus oral progestin combined with metformin in fertility‐preserving treatment for patients with atypical endometrial hyperplasia and early endometrial cancer, and to analyze related factors affecting efficacy.
Pengpeng Gu, Jialu Gao, Yuxin Li, Mei Huang, Xiaoshuang Wang, Xin Zhao   +5 more
wiley   +1 more source

Metabolic profiling and P450 phenotyping of medroxyprogesterone acetate [PDF]

, 2008
Medroxyprogesterone acetate (MPA) is one of the most frequently prescribed progestin for clinical conception, hormone replacement therapy, and adjuvant endocrine therapy. MPA has a low oral bioavailability due to extensive metabolism.
张延延, 张江伟, 葛广波, 李巍, 刘勇, 刘洪涛, 杨凌, 胡卓汉, 刘慧鑫   +8 more
core  

Effect of sexual steroids on the calcium content of aortic atherosclerotic plaque of oophorectomized rabbits

Brazilian Journal of Medical and Biological Research, 2005
We determined the effect of conjugated equine estrogen plus medroxyprogesterone acetate on calcium content of aortic atherosclerotic lesions in oophorectomized adult New Zealand rabbits submitted to a cholesterol rich diet. Five groups of 10 animals each
J.M. Aldrighi, J.R. Lanz, A.P. Mansur, T.L.R. Martinez, J.A.F. Ramires   +4 more
doaj   +1 more source