iMeta, EarlyView.This study suggests that the food‐derived flavonoid hyperoside may act as a natural DExH‐box helicase 9 (DHX9) modulator, directly targeting Thr419 of DHX9 to help resolve pathological R‐loop accumulation. Consequently, it suppresses cyclic GMP‐AMP synthase‐stimulator of interferon genes (cGAS‐STING)‐driven endometrial stromal senescence and restores ...
Yuepeng Jiang +18 more
wiley +1 more source
Indonesian Journal of Obstetrics and Gynecology, 2014 Objective: To determine the comparison of body mass index (BMI) among acceptors of injectable depot medroxyprogesterone acetate (DMPA) with levonorgestrel implant acceptors for 1 year and comparison of lipid profiles between depot medroxyprogesterone ...
Irwan Daido +2 more
doaj +1 more source
Targeting the intratumoral microbiota to overcome cancer immunotherapy resistance
Interdisciplinary Medicine, EarlyView.This review delineates the mechanisms of intratumoral microbiota in cancer immunotherapy resistance, and offers strategies for microbiota‐targeted precision immunotherapy. Abstract Cancer remains a significant global health threat. The tumor microenvironment (TME) is a sophisticated ecological niche that exerts a pivotal effect on treatment outcomes ...
Bufu Tang +14 more
wiley +1 more source
Pulmonary Lymphangioleiomyomatosis: A Case Report in Postmenopausal Woman Treated with Pleurodesis and Progesterone (Medroxyprogesterone Acetate) [PDF]
, 1996 The main problem in the treatment of pulmonary lymphangioleiomyomatosis, which frequently occurs in the reproductive age, is the control of chylothorax and disease progression.
Mario Lise +3 more
core +1 more source
Lipomembranous panniculitis after subcutaneous medroxyprogesterone acetate injections used for buttocks augmentation in Africa [PDF]
, 2021 © 2021 the International Society of DermatologyWe describe a series of four African women with lipomembranous panniculitis after subcutaneous injections of depot medroxyprogesterone acetate (DMPA), a synthetic progestin commonly used as a contraceptive ...
Soares-de-Almeida, Luís +4 more
core +1 more source
International Journal of Gynecology &Obstetrics, Volume 169, Issue 1, Page 421-423, April 2025.
Peter H. Cygan +3 more
wiley +1 more source
Peri‐ and Post‐Menopausal Hormone Replacement Therapy and Voice Disorder Risk: A TriNetX Study
The Laryngoscope, EarlyView.ABSTRACT Objectives The aim of this study was to elucidate the risk of developing voice disorders among peri‐ and post‐menopausal female hormone replacement therapy (HRT) users. Methods A retrospective cohort study was conducted using the TriNetX Global Collaborative Network.
David Kayekjian +4 more
wiley +1 more source
Effects of Progesterone and Its Antagonist Mifepristone on Progesterone Receptor A Expression in Human Umbilical Vein Endothelial Cells [PDF]
, 2009 Effects of female steroid hormones on endothelial cells are gaining increased importance due to several studies on the effects of hormonal treatment on cardiovascular risk.
Ochsenkühn, Robert +6 more
core +1 more source
Characterization of a novel telomerase-immortalized human endometrial stromal cell line, St-T1b
Reproductive Biology and Endocrinology, 2009 Background Coordinated differentiation of the endometrial compartments in the second half of the menstrual cycle is a prerequisite for the establishment of pregnancy. Endometrial stromal cells (ESC) decidualize under the influence of ovarian progesterone
Brosens Jan J +6 more
doaj +1 more source
State Choices, Unequal Access: Policies Shaping Reproductive Health Care Across the United States
The Milbank Quarterly, EarlyView.Policy Points State policies and programs play an outsized role in shaping availability and access to sexual and reproductive health services across the nation. This has a major impact on women's access to contraception, abortion, and maternity services.
ALINA SALGANICOFF +2 more
wiley +1 more source