Results 81 to 90 of about 85,449 (205)

Renal‐vascular axis: unmasking its role in vascular endothelial growth factor‐inhibitor vascular toxicity in cancer patients

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Vascular toxicity is a growing concern in cancer patients receiving vascular endothelial growth factor inhibitor (VEGFi) therapy, posing a significant threat to patient prognosis. While the primary mechanism of VEGFi‐induced vascular toxicity is linked to redox‐sensitive reactions that disrupt vascular tone, leading to hypertension and ...
Grace Whelan, Karla B. Neves
wiley   +1 more source

Management of Non‐Plaque‐Induced Gingival Conditions: A Systematic Review—Part 2: Inflammatory and Immune Conditions; Neoplasms; and Gingival Pigmentation

open access: yesJournal of Clinical Periodontology, EarlyView.
ABSTRACT Aims This systematic review assesses current evidence on the management of non‐plaque (dental biofilm)‐induced gingival diseases and conditions (NPIGDs), including (i) inflammatory and immune conditions, (ii) neoplasms and (iii) gingival pigmentations.
Maria Clotilde Carra   +5 more
wiley   +1 more source

An Unusual Variant of Medullary Carcinoma of Thyroid – A Case Report [PDF]

open access: yesAl Ameen Journal of Medical Sciences, 2011
A 32 years old female presented with midline swelling of neck since 10 years, FNAC of Neck mass was done and diagnosed as Malignant Thyroid neoplasm. On histopathological Examination it was diagnosed as Medullary carcinoma of thyroid - Papillary variant ...
R. Thamil Selvi   +3 more
doaj  

Surgical and clinical strategies in the management of thyroid medullary carcinoma in children with and without ret proto-oncogene mutations

open access: yesThe Turkish Journal of Pediatrics, 2016
Medullary thyroid carcinoma (MTC) may arise sporadically or in familial manner. We presented sporadic and familial cases with MTC in order to raise awareness on management of such patients.
Özlem Boybeyi-Türer   +7 more
doaj   +1 more source

GLP‐1 receptor agonists and serious adverse events: Evidence, uncertainty and clinical implications

open access: yesJournal of Internal Medicine, EarlyView.
Abstract Glucagon‐like peptide‐1 (GLP‐1) receptor agonists provide benefits in weight reduction, glycaemic control in Type 2 diabetes, and cardiovascular and renal outcomes. Their widespread use has given rise to concerns regarding rare but potentially serious adverse events.
Peter Ueda
wiley   +1 more source

Periodontal Medicine Rewired: Mechanisms Linking Periodontitis to Systemic Diseases

open access: yesJournal of Periodontal Research, EarlyView.
This review reorganizes decades of research in periodontal medicine into a multi‐dimensional framework, illustrating how periodontitis influences systemic health through at least seven interconnected mechanisms. ABSTRACT Periodontitis is now recognized not merely as a localized oral condition but as a systemic disease linked to over 70 communicable and
Mario Romandini   +3 more
wiley   +1 more source

GLP‐1 Receptor Agonists and Cancer Risk in Obesity Treatment

open access: yesObesity Reviews, EarlyView.
ABSTRACT Obesity is a well‐established risk factor for numerous cancers, with body habitus, especially central adiposity, contributing to increased cancer incidence and worse prognosis. Glucagon‐like peptide‐1 receptor agonists (GLP‐1 RAs), initially developed to treat Type 2 diabetes, have rapidly gained prominence as powerful anti‐obesity agents due ...
Lorne J. Hofseth   +6 more
wiley   +1 more source

Gastric Medullary Carcinoma with Sporadic Mismatch Repair Deficiency and a TP53 R273C Mutation: An Unusual Case with Wild-Type BRAF

open access: yesCase Reports in Pathology, 2017
Medullary carcinoma has long been recognized as a subtype of colorectal cancer associated with microsatellite instability and Lynch syndrome. Gastric medullary carcinoma is a very rare neoplasm.
Brett M. Lowenthal   +5 more
doaj   +1 more source

CT‐Based Radiomic Features Predict Cervical Lymph Node Metastasis in Dogs With Oral Malignancy: A Machine Learning Study Using Leave‐One‐Patient‐Out Cross‐Validation

open access: yesVeterinary and Comparative Oncology, EarlyView.
ABSTRACT Accurate preoperative identification of cervical lymph node (LN) metastasis is essential for staging and treatment planning in dogs with oral malignancy, yet conventional imaging offers limited diagnostic sensitivity. This retrospective study evaluated whether CT‐derived radiomic features, combined with machine learning classifiers, could ...
Christopher J. Pinard   +5 more
wiley   +1 more source

Two rare tumors, one patient: The first report of bilateral mixed corticomedullary tumors of the adrenal gland

open access: yes
UroPrecision, EarlyView.
Reza Kaffash Nayeri   +3 more
wiley   +1 more source

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