Results 211 to 220 of about 146,670 (267)
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DeckerMed CGSO Case-Based Reviews, 2018
Medullary thyroid cancer (MTC) arises from the thyroid C-cells and accounts for 1 to 2% of thyroid cancers in the United States. Most tumors are sporadic but may occur as a part of the familial syndromes multiple endocrine neoplasia (MEN) 2A, MEN2B, and familial MTC.
Ganapathi Bantwal, Vivek Mathew
semanticscholar +3 more sources
Medullary thyroid cancer (MTC) arises from the thyroid C-cells and accounts for 1 to 2% of thyroid cancers in the United States. Most tumors are sporadic but may occur as a part of the familial syndromes multiple endocrine neoplasia (MEN) 2A, MEN2B, and familial MTC.
Ganapathi Bantwal, Vivek Mathew
semanticscholar +3 more sources
Management of Medullary Thyroid Cancer
Endocrinology and Metabolism Clinics of North America, 2019Medullary thyroid cancer (MTC) is rare but aggressive. It can be cured only if intrathyroid at diagnosis. MTC can be sporadic (75%) or familial (25%) and the 2 forms are distinguished by RET mutations analysis. Calcitonin is the specific serum marker; its doubling time is the most important prognostic factor for survival and progression; 30% of MTC ...
Viola, David, Elisei, Rossella
openaire +4 more sources
Clinical Nuclear Medicine, 2022
A 56-year-old man was diagnosed with calcitonin negative, plasma chromogranin A-positive, immunohistochemistry-negative, high-grade MTC (medullary thyroid cancer) behaving clinically like anaplastic thyroid cancer and presented with progressive disease ...
Sanjana Ballal +8 more
semanticscholar +1 more source
A 56-year-old man was diagnosed with calcitonin negative, plasma chromogranin A-positive, immunohistochemistry-negative, high-grade MTC (medullary thyroid cancer) behaving clinically like anaplastic thyroid cancer and presented with progressive disease ...
Sanjana Ballal +8 more
semanticscholar +1 more source
Phase 3 Trial of Selpercatinib in Advanced RET-Mutant Medullary Thyroid Cancer.
New England Journal of Medicine, 2023BACKGROUND Selpercatinib, a highly selective, potent RET inhibitor, has shown efficacy in advanced RET-mutant medullary thyroid cancer in a phase 1-2 trial, but its efficacy as compared with approved multikinase inhibitors is unclear.
J. Hadoux +23 more
semanticscholar +1 more source
Neoadjuvant Selective RET Inhibitor for Medullary Thyroid Cancer: A Case Series
Thyroid, 2022NA.
Kevin J. Contrera +15 more
semanticscholar +1 more source
Current Treatment Options in Oncology, 2000
Patients with clinically evident medullary thyroid cancer should have a total extracapsular thyroidectomy with bilateral central neck dissection and an ipsilateral prophylactic or therapeutic modified (functional) radical neck dissection when the primary tumor is greater than 1 cm and when the central neck nodes are positive.
E, Kebebew, O H, Clark
+5 more sources
Patients with clinically evident medullary thyroid cancer should have a total extracapsular thyroidectomy with bilateral central neck dissection and an ipsilateral prophylactic or therapeutic modified (functional) radical neck dissection when the primary tumor is greater than 1 cm and when the central neck nodes are positive.
E, Kebebew, O H, Clark
+5 more sources
Surgery, 2022
BACKGROUND This study aimed to clarify whether the extent of thyroidectomy (total thyroidectomy vs thyroid lobectomy) influences survival in adults with localized medullary thyroid cancer.
Weili Liang +9 more
semanticscholar +1 more source
BACKGROUND This study aimed to clarify whether the extent of thyroidectomy (total thyroidectomy vs thyroid lobectomy) influences survival in adults with localized medullary thyroid cancer.
Weili Liang +9 more
semanticscholar +1 more source
Surgery, 2021
BACKGROUND Predictive criteria to determine the absence of node metastases from thyroid specimens are scarce for sporadic medullary thyroid cancer. METHODS Histopathologic stratification of patients with unifocal sporadic medullary thyroid cancer ≤25 ...
A. Machens +7 more
semanticscholar +1 more source
BACKGROUND Predictive criteria to determine the absence of node metastases from thyroid specimens are scarce for sporadic medullary thyroid cancer. METHODS Histopathologic stratification of patients with unifocal sporadic medullary thyroid cancer ≤25 ...
A. Machens +7 more
semanticscholar +1 more source
Otolaryngologic Clinics of North America, 2003
Medullary thyroid cancer is a rare neoplasm that arises from the parafollicular C cells. It occurs in a sporadic form, or less commonly as a hereditary form, as part of multiple endocrine neoplasia syndromes types 2A and 2B. The RET proto-oncogene is currently the primary factor that is implicated in the hereditary forms of this neoplasm. The knowledge
Gary L, Clayman, Tarek S, el-Baradie
openaire +2 more sources
Medullary thyroid cancer is a rare neoplasm that arises from the parafollicular C cells. It occurs in a sporadic form, or less commonly as a hereditary form, as part of multiple endocrine neoplasia syndromes types 2A and 2B. The RET proto-oncogene is currently the primary factor that is implicated in the hereditary forms of this neoplasm. The knowledge
Gary L, Clayman, Tarek S, el-Baradie
openaire +2 more sources
Thyroid, 2020
Background: Measurements of both basal (b) calcitonin (CT) and calcium (Ca)-stimulated CT (Ca-sCT) levels are performed to identify medullary thyroid cancer (MTC) at an early stage when used as part of the diagnostic workup of thyroid nodules (CT ...
M. Niederle +5 more
semanticscholar +1 more source
Background: Measurements of both basal (b) calcitonin (CT) and calcium (Ca)-stimulated CT (Ca-sCT) levels are performed to identify medullary thyroid cancer (MTC) at an early stage when used as part of the diagnostic workup of thyroid nodules (CT ...
M. Niederle +5 more
semanticscholar +1 more source