Results 91 to 100 of about 124,817 (274)

Molecular Diagnostics in Thyroid Nodules: Current Applications, Clinical Value, and Future Perspective

open access: yesMed Research, EarlyView.
ABSTRACT Molecular diagnostics have become an important adjunct to ultrasonography and fine‐needle aspiration (FNA) for thyroid nodules, especially in Bethesda III/IV cytology where malignancy risk is uncertain. This narrative review summarizes the diagnostic and prognostic value of key genomic drivers (BRAF V600E, RAS, RET, TERT, and selected fusions)
Guohui Xiao   +14 more
wiley   +1 more source

Thyroxine-binding globulin: investigation of microheterogeneity [PDF]

open access: yes, 1981
Preparations of T4-binding globulin (TBG) from human serum was performed using only two affinity chromatography steps. Purity of the protein was demonstrated by a single band in overloaded disc and sodium dodecyl sulfate electrophoresis, equimolar ...
Gärtner, Roland   +4 more
core   +1 more source

Association of Glucagon‐Like Peptide‐1 Receptor Agonists With Cancer Risk in Older Adults With Type 2 Diabetes

open access: yesObesity, EarlyView.
ABSTRACT Objective The real‐world evidence on the association between glucagon‐like peptide‐1 receptor agonists (GLP‐1RAs) and cancer risk remains limited and mixed. Methods In 2013–2020 national Medicare claims data, we included cancer‐naïve patients with type 2 diabetes (T2D). We identified those who initiated GLP‐1 RA, sodium‐glucose cotransporter 2
Ying Lu   +13 more
wiley   +1 more source

Surgical and clinical strategies in the management of thyroid medullary carcinoma in children with and without ret proto-oncogene mutations

open access: yesThe Turkish Journal of Pediatrics, 2016
Medullary thyroid carcinoma (MTC) may arise sporadically or in familial manner. We presented sporadic and familial cases with MTC in order to raise awareness on management of such patients.
Özlem Boybeyi-Türer   +7 more
doaj   +1 more source

Mixed Medullary-Follicular Carcinoma of the Thyroid [PDF]

open access: yes, 1999
Mixed medullary-follicular thyroid carcinoma is an uncommon tumor that consists of both follicular and parafollicular cells. Case.We report a 43-year-old woman with a palpable mass in the right side of the neck.
Bahmanyar, Mohammad   +3 more
core  

Mutational Analysis in Pediatric Thyroid Cancer and Correlations with Age, Ethnicity, and Clinical Presentation. [PDF]

open access: yes, 2016
BackgroundWell-differentiated thyroid cancer (WDTC) incidence in pediatrics is rising, most being papillary thyroid carcinoma (PTC). The objective of the study was to assess the prevalence of different mutations in pediatric WDTC and correlate the ...
Cheng, Shih-Min   +9 more
core   +1 more source

Fibrosis‐Driven Surgical Risk After Thyroid Nodule Ablation: Quantitative Clinicopathological Determinants of Complications in Post‐Ablative Thyroidectomy—A Retrospective Cohort Study

open access: yesWorld Journal of Surgery, EarlyView.
Thermal ablation is increasingly used for selected benign and low‐risk thyroid nodules, yet some patients still require thyroidectomy for regrowth, persistent symptoms, or new oncologic concern. The surgical and pathological impact of ablation‐induced remodeling remains incompletely defined.
Daqi Zhang   +7 more
wiley   +1 more source

Incidence of thyroid cancer in Golestan province of Iran: Some initial observations [PDF]

open access: yes, 2008
Objectives: The incidence of thyroid cancer is increasing in several countries. The main aim of this study was to find and describe province-specific estimates of incidence in males and females by age groups for thyroid cancer. Methodology: The data used
Kabir, M.J., Marjani, A.
core  

Renal‐vascular axis: unmasking its role in vascular endothelial growth factor‐inhibitor vascular toxicity in cancer patients

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Vascular toxicity is a growing concern in cancer patients receiving vascular endothelial growth factor inhibitor (VEGFi) therapy, posing a significant threat to patient prognosis. While the primary mechanism of VEGFi‐induced vascular toxicity is linked to redox‐sensitive reactions that disrupt vascular tone, leading to hypertension and ...
Grace Whelan, Karla B. Neves
wiley   +1 more source

An Unusual Variant of Medullary Carcinoma of Thyroid – A Case Report [PDF]

open access: yesAl Ameen Journal of Medical Sciences, 2011
A 32 years old female presented with midline swelling of neck since 10 years, FNAC of Neck mass was done and diagnosed as Malignant Thyroid neoplasm. On histopathological Examination it was diagnosed as Medullary carcinoma of thyroid - Papillary variant ...
R. Thamil Selvi   +3 more
doaj  

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