Results 91 to 100 of about 46,412 (225)

Synergistic antitumour activity of RAF265 and ZSTK474 on human TT medullary thyroid cancer cells [PDF]

open access: yes, 2015
Medullary thyroid cancer (MTC) is an aggressive malignancy responsible for up to 14% of all thyroid cancer-related deaths. It is characterized by point mutations in the rearranged during transfection (RET) proto-oncogene.
Barollo, Susi   +11 more
core   +1 more source

Lower Risk of Cardiovascular Events in Patients With Clinical Atherosclerotic Cardiovascular Disease Who Initiated Semaglutide 2.4 mg in the Real‐World: Results From the SCORE—Clinical ASCVD Study

open access: yesDiabetes, Obesity and Metabolism, Volume 28, Issue 6, Page 4975-4990, June 2026.
ABSTRACT Aims To evaluate the association between semaglutide 2.4 mg and major adverse cardiovascular events (MACE) among adults with clinical atherosclerotic cardiovascular disease (ASCVD) and overweight/obesity without diabetes in real‐world clinical practice.
Michael G. Nanna   +10 more
wiley   +1 more source

Medullary thyroid carcinoma

open access: yesActa clinica Croatica, 1999
Medullary thyroid carcinoma (MTC) is an uncommon thyroid tumor accounting for only 3%-5% of all thyroid malignancies. Nevertheless, it has attracted a great deal of interest for its distinctive biochemical and genetic features and unique clinical associations, with a predilection for early diagnosis and an appropriate surgical approach.
Mateša, Neven   +6 more
openaire   +3 more sources

Atypical Presentation of a Medullary Thyroid Carcinoma Producing Acth and Serotonin

open access: yesCase Reports in Oncology, 2019
Medullary carcinoma accounts for about 5% of all thyroid malignancies. The tumor may produce other hormones in addition to calcitonin that typically occurs in the presence of distant metastases.
Mariana Ferreira   +4 more
doaj   +1 more source

RET proto-oncogene and thyroid cancer [PDF]

open access: yes, 2018
TheRET proto-oncogene has not only conclusively been identified as responsible for the three subtypes of the inherited cancer syndrome multiple endocrine neoplasia type 2 (MEN-2) but also shown to be involved in the molecular evolution of sporadic ...
Komminoth, Paul
core  

Changes in the 6th edition of the World Health Organization classification of tumours of the digestive system

open access: yesHistopathology, Volume 88, Issue 7, Page 1295-1314, June 2026.
Changes and new entities in the 6th edition WCT of the digestive system, including structural, molecular, and diagnostic updates to standardize terminology and improve clinical relevance. Epithelial tumours are organized by site; neuroendocrine, mesenchymal and haematolymphoid tumours have dedicated chapters, with refined grading, redefined ...
Mark J Arends   +48 more
wiley   +1 more source

Expression of FAS/APO 1/CD 95 in thyroid tumors.

open access: yesFolia Histochemica et Cytobiologica, 2007
Using immunohistochemistry, Fas/Apo-1 protein expression was investigated in thyroid cancers of 67 patients. Thyroid biopsies from twenty eight patients with benign thyroid diseases were also examined.
Waldemar Balcerzak   +5 more
doaj   +1 more source

Development of a Machine Learning‐Based Predictive Model for Central Lymph Node Metastasis in Papillary Thyroid Microcarcinoma

open access: yesCancer Medicine, Volume 15, Issue 5, May 2026.
ABSTRACT Background Central lymph nodes metastasis (CLNM) is common in papillary thyroid. Microcarcinoma (PTMC). Whilst prophylactic central lymph node dissection (CLND) can prevent further CLNM, it remains controversial. An accurate model to predict CLNM is therefore necessary for patients with PTMC.
Tao Li   +3 more
wiley   +1 more source

Diagnostic Utility of a Cost‐Effective Four‐Gene Next Generation Sequencing Panel for Predicting Papillary Thyroid Carcinoma in Indeterminate Thyroid Cytology: A Multicenter Study in China

open access: yesCancer Medicine, Volume 15, Issue 5, May 2026.
This multicenter study of 827 thyroid nodules demonstrates that a targeted NGS 4‐gene panel (BRAF^V600E, TERT promoter, RET fusions, NTRK3 fusion) achieves high diagnostic accuracy (88.2%) and PPV (99.62%) for cytologically indeterminate Bethesda III–V nodules, offering a cost‐effective first‐line molecular test in China. ABSTRACT Molecular testing has
Qiong Jiao   +8 more
wiley   +1 more source

A decrease of calcitonin serum concentrations less than 50 percent 30 minutes after thyroid surgery suggests incomplete C-cell tumor tissue removal [PDF]

open access: yes, 2010
The prognosis of medullary thyroid carcinoma (MTC) depends on the completeness of the first surgical treatment. To date, it is not possible to predict whether the tumor has been completely removed after surgery.
A. Colao   +25 more
core   +1 more source

Home - About - Disclaimer - Privacy