Results 61 to 70 of about 124,817 (274)

Mutations of the ret protooncogene in German multiple endocrine neoplasia families: Relation between genotype and phenotype. [PDF]

, 1996
It has been suggested that not only the position but also the nature of the mutations of the ret protooncogene strongly correlate with the clinical manifestation of the multiple endocrine neoplasm type 2 (MEN 2) syndrome.
Deckart, H. F., Dralle, H., Frank-Raue, K., Frilling, A., Haase, R., Hampel, R., Höppner, W., Kirchner, R., Klempa, J., Kotzerke, J., Mann, K., Raue, F., Rendl, J., Ritter, M. M., Scholz, G. H., Seif, F.   +15 more
core   +1 more source

Paediatric development of radiopharmaceutical imaging agents and radioligand therapeutics

British Journal of Clinical Pharmacology, EarlyView.
Abstract This review focuses on the development of radiopharmaceutical imaging agents and radioligand therapeutics for paediatric use. Nuclear medicine plays an important role in the diagnosis and treatment of various childhood conditions, including cancers, infections and brain disorders.
Justin L. Hay, Amandine Manon, Hunter Stephens, S. Y. Amy Cheung, Bart de Keizer, Erik T. te Beek   +5 more
wiley   +1 more source

Mixed medullary-papillary carcinoma of the thyroid: Report of two cases and review of the literature

Indian Journal of Pathology and Microbiology, 2014
Papillary thyroid carcinoma (PTC) and medullary thyroid carcinoma (MTC) are two distinct types of thyroid carcinoma with considerable difference in terms of cellular origin, histopathological appearance, clinical course and prevalence.
Eren Gurkan, Yesim Gurbuz, Ilhan Tarkun, Zeynep Canturk, Berrin Cetinarslan   +4 more
doaj   +1 more source

Analysis of thyroid carcinomas with immunohistochemical panel application: retrospectively study of 52 cases [PDF]

Ķazaķstannyṇ Klinikalyķ Medicinasy, 2019
Aim: The aim of this study was to share our cases of thyroid carcinoma with the literature and to emphasize the importance of evaluation with an immunohistochemical panel in cases with difficulty in the differential diagnosis.
Mecdi Gurhan Balci, Mahir Tayfur
doaj   +1 more source

Prognostic Impact of miR-224 and RAS Mutations in Medullary Thyroid Carcinoma [PDF]

, 2017
Little is known about the function of microRNA-224 (miR-224) in medullary thyroid cancer (MTC). This study investigated the role of miR-224 expression in MTC and correlated it with mutation status in sporadic MTCs.
BAROLLO, SUSI, BENNA, CLARA, BERTAZZA, LORIS, CAVEDON, ELISABETTA, CENSI, SIMONA, GALUPPINI, FRANCESCA, IACOBONE, MAURIZIO, MIAN, CATERINA, NACAMULLI, DAVIDE, PENNELLI, GIANMARIA, Vianello, Federica, WATUTANTRIGE FERNANDO, SARA, Zovato, Stefania   +12 more
core   +3 more sources

Comparative efficacy of GLP‐1 RA, tirzepatide and SGLT‐2 inhibitors in metabolic liver disease: A network meta‐analysis

British Journal of Clinical Pharmacology, EarlyView.
Aim Metabolic liver disease, including nonalcoholic fatty liver disease (NAFLD) and nonalcoholic steatohepatitis, is a major cause of chronic liver dysfunction worldwide, creating an urgent need for effective treatments. This systematic literature review (SLR) and network meta‐analysis (NMA) systematically reviews and compares the efficacy and safety ...
Andrej Belančić, Christina Antza, Anastasios Poutachidis, Smaro Palaska, Elvira Meni Maria Gkrinia, Andrea Katrin Faour, Yusuf Ziya Sener, Seher Sener, Rehena Sultana   +8 more
wiley   +1 more source

Diagnostic efficiency of existing guidelines and the AI-SONIC™ artificial intelligence for ultrasound-based risk assessment of thyroid nodules

Frontiers in Endocrinology, 2023
IntroductionThe thyroid ultrasound guidelines include the American College of Radiology Thyroid Imaging Reporting and Data System, Chinese-Thyroid Imaging Reporting and Data System, Korean Society of Thyroid Radiology, European-Thyroid Imaging Reporting ...
Linxin Yang, Linxin Yang, Ning Lin, Ning Lin, Mingyan Wang, Gaofang Chen   +5 more
doaj   +1 more source

Concurrent Medullary Carcinoma and Hashimoto’s Thyroiditis: A Case Report with an Emphasis on US Features

Journal of the Korean Society of Radiology, 2023
Medullary thyroid carcinoma (MTC) is a rare malignancy that originates from the parafollicular cells of the thyroid gland. Hashimoto’s thyroiditis (HT) is an autoimmune thyroid disease and is the most common cause of hypothyroidism.
Hyoung Yeob Kim, Noh Hyuck Park
doaj   +1 more source

Prophylactic thyroidectomy in ethnic Chinese patients with multiple endocrine neoplasia type 2A syndrome after the introduction of genetic testing [PDF]

, 2009
Objective: To evaluate the impact of genetic testing in the management of familial multiple endocrine neoplasia 2A patients. Design: Retrospective study. Setting: University teaching hospital, Hong Kong.
GarciaBarcelo, MM, Lam, KSL, Lang, BHH, Lau, GSK, Lo, CY, Tam, PK, Tso, A   +6 more
core  

A decrease of calcitonin serum concentrations less than 50 percent 30 minutes after thyroid surgery suggests incomplete C-cell tumor tissue removal [PDF]

, 2010
The prognosis of medullary thyroid carcinoma (MTC) depends on the completeness of the first surgical treatment. To date, it is not possible to predict whether the tumor has been completely removed after surgery.
A. Colao, A. Faggiano, American Thyroid Association Guidelines Task Force, Kloos, Costante, Dralle, Dralle, F. Milone, G. Lombardi, Gharib, Grauer, I. Ventre, Inabnet, L. Pezzullo, Leboulleux, M. G. Chiofalo, Machens, Machens, Machens, Moley, R. Giannattasio, R. Severino, Rago, Scheuba, Scollo, V. Ramundo, Wells Jr   +25 more
core   +1 more source