Results 121 to 130 of about 71,273 (273)

Tumor-associated macrophages correlate with better outcome in SHH medulloblastoma

Frontiers in Oncology
ObjectiveTumor-associated macrophages (TAMs) constitute a significant proportion of the immune cell population within brain tumors. The polarization of macrophages exerts an important influence on the tumor microenvironment (TME).
Jin Zhang, Shuting Li, Yuan Wang, Jingjing Liu, Yan Liu, Xiaojun Gong, Yanling Sun, Liming Sun, Zhigang Li, Tianyou Wang, Shuxu Du, Wanshui Wu   +11 more
doaj   +1 more source

Attention and Memory Functioning Among Pediatric Patients with Medulloblastoma [PDF]

, 2005
Cara Reeves, Shawna L. Palmer, Wilburn E. Reddick, Thomas E. Merchant, Gray M. Buchanan, Amar Gajjar, Raymond K. Mulhern   +6 more
openalex   +1 more source

Neuro‐Immune Crosstalk: Molecular Mechanisms, Biological Functions, Diseases, and Therapeutic Targets

MedComm, Volume 7, Issue 2, February 2026.
Neurons, immune cells, and other cellular components within the disease microenvironment (such as stromal cells and tumor cells) constitute a dynamically evolving ecosystem. Neurons directly modulate immune cell activity and inflammatory responses through the release of neurotransmitters (e.g., norepinephrine and CGRP), while also promoting tumor ...
Xin Guo, Hui Liu, Yu‐Jing Song, Jian‐Hua Wang, Danfeng Liu, Zhi‐Wei Zheng, Jia‐Jun Li, Boya Li, An Song, Wei He, Lei‐Lei Yang, Shuo Wang   +11 more
wiley   +1 more source

Medulloblastoma (?) [PDF]

Proceedings of the Royal Society of Medicine, 1931
C, Worster-Drought, W E, Dickson
openaire   +2 more sources

Mechanisms of enhancer‐driven oncogene activation

International Journal of Cancer, Volume 158, Issue 2, Page 333-341, 15 January 2026.
Abstract An aggressive subtype of acute myeloid leukemia (AML) is caused by enhancer hijacking resulting in MECOM overexpression. Several chromosomal rearrangements can lead to this: the most common (inv(3)/t(3;3)) results in a hijacked GATA2 enhancer, and there are several atypical MECOM rearrangements involving enhancers from other hematopoietic ...
Joyce Vriend, Ruud Delwel, Dorien Pastoors   +2 more
wiley   +1 more source

Inhibition of STAT3: A promising approach to enhancing the efficacy of chemotherapy in medulloblastoma

Translational Oncology
Medulloblastoma is a type of brain cancer that primarily affects children. While chemotherapy has been shown to be effective in treating medulloblastoma, the development of chemotherapy resistance remains a challenge.
Sachindra Kumar, Dube Aakash Arwind, Harish Kumar B, Samyak Pandey, Raksha Nayak, Megh Pravin Vithalkar, Nitesh Kumar, K Sreedhara Ranganath Pai   +7 more
doaj   +1 more source

Differences in the Prognostic Value of Tumor Extent of Resection among the Molecular Subgroups of Medulloblastoma: A Single Centre Study of 113 Cases

Brain Science Advances, 2017
Medulloblastoma (MB) is one of the most common pediatrics malignant tumors of the central nervous system. Studies in America and Europe have demonstrated significant differences in the prognostic value of medulloblastoma extent among molecular subgroups ...
Yuyuan Wang, Kay Kawai Li, Ji Xiong, Zhenyu Zhang, Yang Wang, Jian Xu, Yin Wang, Hokeung Ng, Ping Zhong   +8 more
doaj   +1 more source

Transcriptional landscape of neuronal and cancer stem cells [PDF]

, 2013
Tumor mass is composed by heterogeneous cell population including a subset of “cancer stem cells” (CSC). Oncogenic signals foster CSC by transforming tissue stem cells or by reprogramming progenitor/differentiated cells towards stemness.
Miele, Evelina
core  

Enhancer‐dependent gene regulation in space, time, and malignancies

International Journal of Cancer, Volume 158, Issue 2, Page 357-367, 15 January 2026.
Abstract Control of cell‐type‐specific gene activation requires the coordinated activity of distal regulatory elements, including enhancers, whose inputs must be temporally integrated. Dysregulation of this regulatory capacity, such as aberrant usage of enhancers, can result in malignant transformation of cells.
Belinda Blum, Victoria Dachtler, Angelika Feldmann   +2 more
wiley   +1 more source

TMOD-01BCOR IS A NOVEL TUMOR SUPPRESSOR GENE IN SHH-DRIVEN MEDULLOBLASTOMA [PDF]

, 2015
Nadja V. Batora, Marcus Giese, Laura Sieber, Stefan M. Pfister, Vivian J. Bardwell, Daisuke Kawauchi, Paul A. Northcott   +6 more
openalex   +1 more source