Results 121 to 130 of about 41,471 (240)

Medulloblastoma (?) [PDF]

Proceedings of the Royal Society of Medicine, 1931
C, Worster-Drought, W E, Dickson
openaire   +2 more sources

Medulloblastoma – heterogeneous histopathology

, 2011
Medulloblastoma is the most common paediatric brain tumour. It is a malignant embryonal tumour of the cerebellum with predominantly neuronal differentiation and tendency to metastasises via CSF pathways.
Grajkowska, Wiesława
core  

Identification of tumor rejection antigens and the immunologic landscape of medulloblastoma

Genome Medicine
Background The current standard of care treatments for medulloblastoma are insufficient as these do not take tumor heterogeneity into account. Newer, safer, patient-specific treatment approaches are required to treat high-risk medulloblastoma patients ...
Changlin Yang, Vrunda Trivedi, Kyle Dyson, Tongjun Gu, Kate M. Candelario, Oleg Yegorov, Duane A. Mitchell   +6 more
doaj   +1 more source

Exploiting Integrin-αVβ3 to Enhance Radiotherapy Efficacy in Medulloblastoma via Ferroptosis

Current Oncology
Medulloblastoma, a malignant pediatric brain tumor, has a poor prognosis upon relapse, highlighting a critical clinical need. Our previous research linked medulloblastoma cell radioresistance to integrin-αvβ3 expression.
Célia Gotorbe, Fabien Segui, William Echavidre, Jérôme Durivault, Thays Blanchard, Valérie Vial, Marina Pagnuzzi-Boncompagni, Rémy Villeneuve, Régis Amblard, Nicolas Garnier, Cécile Ortholan, Benjamin Serrano, Vincent Picco, Jacques Pouysségur, Milica Vucetic, Christopher Montemagno   +15 more
doaj   +1 more source

Targeting protein synthesis pathways in MYC-amplified medulloblastoma

Discover Oncology
MYC is one of the most deregulated oncogenic transcription factors in human cancers. MYC amplification/or overexpression is most common in Group 3 medulloblastoma and is positively associated with poor prognosis.
Devendra Kumar, Ranjana Kanchan, Nagendra K. Chaturvedi   +2 more
doaj   +1 more source

Neuropsychological sequelae of paediatric posterior fossa brain tumours : the effect on quality of life

, 2002
Bibliography: leaves 248 ...
Leng, Jeanette Anne
core  

Illuminating Medulloblastoma

, 2019
Medulloblastoma, a childhood brain cancer of the cerebellum, has one of the highest mortality rates of pediatric cancers. For over a century, scientists believed that medulloblastoma metastasized exclusively through cerebrospinal fluid; however, novel ...
Woolridge, Nicholas, Dryer, Marc, Daniels, Craig, Rastan, Avesta, Taylor, Michael   +4 more
core   +1 more source

Current medulloblastoma subgroup specific clinical trials

, 2020
Medulloblastoma is a heterogeneous disease with at least four distinct molecular subgroups: wingless (WNT), sonic hedgehog (SHH), Group 3, and Group 4. Recently there has been considerable progress defining the molecular drivers and prognostic factors of
D Ashley (12372034), D Landi (13500667), EM Thompson (14470794)   +2 more
core  

Medulloblastoma Circulating Tumor Cells Form Leptomeningeal Metastases

, 2018
NCAM+CD45+ medulloblastoma cells were shown to be medulloblastoma circulating tumor cells (CTC).

core   +1 more source

Medulloblastoma: Classification (A Review)

, 2012
Medulloblastomas (MBs) represent a heterogeneous group of highly malignant primary tumors of the Central Nervous System (CNS), with prevalence in male and young age patients.
Caracciolo V., Giordano A.
core   +1 more source