Results 141 to 150 of about 71,273 (273)
Targeting protein synthesis pathways in MYC-amplified medulloblastoma
Discover OncologyMYC is one of the most deregulated oncogenic transcription factors in human cancers. MYC amplification/or overexpression is most common in Group 3 medulloblastoma and is positively associated with poor prognosis.
Devendra Kumar +2 more
doaj +1 more source
Exploiting Integrin-αVβ3 to Enhance Radiotherapy Efficacy in Medulloblastoma via Ferroptosis
Current OncologyMedulloblastoma, a malignant pediatric brain tumor, has a poor prognosis upon relapse, highlighting a critical clinical need. Our previous research linked medulloblastoma cell radioresistance to integrin-αvβ3 expression.
Célia Gotorbe +15 more
doaj +1 more source
PM-09 * REGULATION OF MEDULLOBLASTOMA FORMATION BY Gfi1 AND Gfi1B [PDF]
, 2014 C. Lee +6 more
openalex +1 more source
Congenital medulloblastoma [PDF]
Archives of Disease in Childhood - Fetal and Neonatal Edition, 2006 B, Ermis +5 more
openaire +3 more sources
Archiv der Pharmazie, Volume 359, Issue 1, January 2026.Focusing on the discovery of new therapeutics for childhood cancer, novel quinoline derivatives were synthesized and demonstrated activity against Ewing sarcoma. A target search was performed against a panel of kinases, and the compounds showed selectivity for the NAK family, mainly GAK, which was confirmed by enzyme kinetic assays.
Caroline de Bem Gentz +17 more
wiley +1 more source
Tumour-associated macrophages exhibit anti-tumoural properties in Sonic Hedgehog medulloblastoma
, 2019 Victor Maximov +11 more
openalex +1 more source
926 LONG TERM ENDOCRINE SEQUELAE IN MEDULLOBLASTOMA PATIENTS [PDF]
, 1985 Sharon E. Oberfield +3 more
openalex +1 more source
Basal Cell Nevus Syndrome Treated With Laser Therapy: Novel Approach for Young Adults
International Journal of Dermatology, Volume 65, Issue 2, Page 362-364, February 2026.
Giulia Briatico +4 more
wiley +1 more source
Clinical and Translational Medicine, Volume 16, Issue 1, January 2026.Application of synthetic lethality screening in drug resistance models. Abstract Background and Rationale Synthetic lethality (SL)‐based strategies hold significant promise for overcoming therapeutic resistance, a critical bottleneck in cancer treatment where cancer cells evade anticancer therapies, leading to diminished efficacy or treatment failure ...
Junyan Li +4 more
wiley +1 more source