Results 111 to 120 of about 262 (165)

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

Aging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang, Zhong Fan, Runmeng Liu, Xiaotian Zhang   +3 more
wiley   +1 more source

Long‐Term Follow‐Up of Chemotherapy‐Associated Biological Aging in Women With Early Breast Cancer

Aging and Cancer, EarlyView.
Women threated with adjuvant chemotherapy for early breast cancer have sustained long‐term increase in p16INK4a,, a robust marker of cell senescence, suggesting a chemotherapy‐associated age acceleration. p16INK4a as well as other biomarkers may identify patients at greatest risk for senescence‐related diseases of aging.
Hyman B. Muss, Alexis C. Wardell, Allison M. Deal, Kirsten A. Nyrop, Allison Ross, Yara G. Abdou, Jeffrey D. Aldrich, Lisa A. Cary, E. Claire Dees, Katherine E. Reeder‐Hayes, Emily M. Ray, Natalia Mitin, Denis Tsygankov   +12 more
wiley   +1 more source

Risk Prediction Models for Recurrence After Curative Treatment of Early‐Stage or Locally Advanced Lung Cancer: A Systematic Review

Aging and Cancer, EarlyView.
This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel, S. Tissera, E. Paul, J. Zalcberg, R. G. Stirling   +4 more
wiley   +1 more source

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IMPROVE THE INVESTMENT ENVIRONMENT TO STRENGTHEN ATTRACT FOREIGN INVESTMENT IN VIETNAM

International journal of social science and economic research, 2023
The World Bank (WB) has forecast the lowest growth outlook for the global market since 1993 with a growth rate of 1.7% (except for the two years of the Covid 19 pandemic).
Dr. Nguyen the Hung
semanticscholar   +1 more source

Secondary Grammar Education in the Middle Ages

The History of Grammar in Foreign Language Teaching, 2020
The study of language and literature had a fundamental role in medieval education, being a major subject at all levels of education. This chapter deals with medieval language teaching in Western Christendom, focusing on the core of grammatical treatises,
A. Luhtala
semanticscholar   +1 more source

Improving the specificity of uniparametric low-field magnetic resonance imaging in prostate cancer assessment in resource-limited settings

Journal of Radiation Medicine in the Tropics, 2023
Background: Due to infrastructural and financial constraints, public institutions in low- and middle-income countries (LMICs) use low-field magnetic resonance imaging (LFMRI) systems, which limits the possibility for global guideline conformity ...
I. C Chibuzo, A. Smart, A. Takure, B. Osobu, J. Rimande, G. Ogbole   +5 more
semanticscholar   +1 more source

Arisan

Community Economies in the Global South, 2022
Arisan is an Indonesian economic practice which has been in existence for hundreds of years, and is believed to have been brought to Indonesia by Chinese merchants interacting with the Orang Asli Indigenous people.
Ririn Haryani, K. Dombroski
semanticscholar   +1 more source

Building and Maintaining Trust in Virtual Teams

Handbook of Research on Remote Work and Worker Well-Being in the Post-COVID-19 Era, 2021
The COVID-19 pandemic has led to widespread adoption of virtual teams (VTs), the prevalence of which had already been increasing steadily. However, studies show that VTs often fail to meet their potential, highlighting the centrality of trust to their ...
C. Hughes, Marc N. K. Saunders
semanticscholar   +1 more source

The Politics of Low-Carbon Energy in Iran and Iraq

Low Carbon Energy in the Middle East and North Africa, 2021
Both Iran and Iraq are major oil producers; both have abundant hydroelectric, solar and wind potential, and face fast-rising energy demand which they have been challenged to meet. Yet both have struggled to adopt low-carbon energy on a large scale.
Robin Mills
semanticscholar   +1 more source

Microstructure and Hardness of Borided Layer on SKD61 Steel

2020 5th International Conference on Green Technology and Sustainable Development (GTSD), 2020
In this study, mechanical properties of boride formed on AISI H13 steel substrate were investigated. The steel has high chromium content and have a widespread use in the engineering application. Boriding treatment was carried out in a mixture of 30% SiC +
N. Pham, L. N. Nguyen, The-San Tran
semanticscholar   +1 more source