Results 151 to 160 of about 150,521,404 (284)
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
State Laws Supporting Adapted Physical Education Access and Quality for Students With Disabilities. [PDF]
J Sch HealthPiekarz-Porter E +4 more
europepmc +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Self-Rated Health Associated with Chronic Diseases and Types of Physical Activity Among Middle-Aged and Older Adults: A Cross-Sectional Study Using Explainable Machine Learning. [PDF]
J Clin MedYang T, Choi Y, Kim Y, Song M.
europepmc +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Numeric Simulation of Electric Powertrain for Automotive Application
, 2019 Air pollution level in an urban area is a noteworthy concern among many countries. In the continuous quest for innovating new technology to improve the fuel economy and reduce greenhouse gas emissions levels from the automotive vehicle, the automotive ...
Meet, Shah
core
Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
Study on microstructure and properties of titanium alloy wall fabricated by laser-TIG arc. [PDF]
PLoS OneLi M, Guo Y, Wang S.
europepmc +1 more source
Meet-in-the-Middle Attacks on AES
, 2013 Cette thèse est dédiée à la cryptanalyse de l'AES (Advanced Encryption Standard) qui est l'un des systèmes de chiffrement par bloc les plus répandu dans le monde. Nous y présentons une nouvelle technique pour résoudre un type particulier d'équations spécialement conçu pour attaquer l'AES.
openaire +1 more source
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source