Results 31 to 40 of about 2,274,378 (251)
Molecular Oncology, EarlyView.TOMM20 increases cancer aggressiveness by maintaining a reduced state with increased NADH and NADPH levels, oxidative phosphorylation (OXPHOS), and apoptosis resistance while reducing reactive oxygen species (ROS) levels. Conversely, CRISPR‐Cas9 knockdown of TOMM20 alters these cancer‐aggressive traits.
Ranakul Islam +9 more
wiley +1 more source
Molecular Oncology, EarlyView.Trastuzumab‐deruxtecan, a HER2‐targeting antibody‐drug conjugate, shows promising antitumor activity in head and neck squamous cell carcinoma with low HER2 expression. In vitro and in vivo studies demonstrated dose‐dependent cell death and tumor growth reduction in low HER2‐expressing cell lines, which correlated with drug accumulation measured using a
Abdullah Bin Naveed +8 more
wiley +1 more source
Computer Algebra Applications for Numerical Relativity [PDF]
, 2003 We discuss the application of computer algebra to problems commonly arising in numerical relativity, such as the derivation of 3+1-splits, manipulation of evolution equations and automatic code generation.
Husa, Sascha, Lechner, Christiane
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Prevalence of dosing errors in elderly patients with impaired renal function: a survey in ambulatory patients [meeting abstract] [PDF]
, 2010 Meeting Abstract : Gesellschaft für Arzneimittelanwendungsforschung und Arzneimittelepidemiologie e.V. (GAA). 17. Jahrestagung der Gesellschaft für Arzneimittelanwendungsforschung und Arzneimittelepidemiologie. Osnabrück, 25.-26.11.2010.
Harder, Sebastian, Roehl, Ina
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Molecular Oncology, EarlyView.Comprehensive cancer centre (CCCs) and CCCs of Excellence (CCCoE) integration in healthcare. Through outreach to surrounding community hospitals, CCCs enable wider access to top‐clinical cancer treatments and care, thereby facilitating the swift enrolment of patients into data‐rich clinical trials (PI‐initiated trials testing new concepts, drug ...
Anton Berns +4 more
wiley +1 more source
Market uptake of pegylated interferons for the treatment of hepatitis C in Europe : meeting abstract [PDF]
, 2008 Introduction and Objectives Hepatitis C virus (HCV) infection is a leading cause of chronic liver disease with life threatening sequelae such as end-stage liver cirrhosis and liver cancer.
Lettmeier, Beate +5 more
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, 2012 We have performed broad-band zero-field and magneto-infrared spectroscopy of the three dimensional topological insulator Bi$_{0.91}$Sb$_{0.09}$. The zero-field results allow us to measure the value of the direct band gap between the conducting $L_a$ and ...
Ando, Yoichi +6 more
core +1 more source
Determinants of gain modulation enabled by short-term depression at an inhibitory cerebellar synapse [PDF]
, 2014 from the 23rd Annual Computational Neuroscience Meeting: CNS 2014. © 2014 Bampasakis et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org ...
D Bampasakis +8 more
core +2 more sources
Genomics‐led approach to drug testing in models of undifferentiated pleomorphic sarcoma
Molecular Oncology, EarlyView.GA text Genomic data from undifferentiated pleomorphic sarcoma patients and preclinical models were used to inform a targeted drug screen. Selected compounds were tested in 2D and 3D cultures of UPS cell lines. A combination of trametinib and infigratinib was synergistic in the majority of UPS cell lines tested, which was further confirmed in an ex ...
Piotr J. Manasterski +19 more
wiley +1 more source
A room temperature indirect formic acid fuel cell [PDF]
, 2010 Session B-1.2: Vehicle, Gas Processing/Storage, Direct-Fuel FCspublished_or_final_versionThe 218th Meeting of the Electrochemical Society (ECS Meeting 2010), Las Vegas, NV., 10-15 October 2010. In Electrochemical Society Meeting Abstracts, 2010, abstract
Chan, KY +4 more
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