Results 41 to 50 of about 7,904,020 (349)
FEBS Letters, EarlyView.B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro +2 more
wiley +1 more source
From omics to AI—mapping the pathogenic pathways in type 2 diabetes
FEBS Letters, EarlyView.Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan +2 more
wiley +1 more source
Majalah Kardiologi Indonesia, 2022 Indonesian Society of Interventional Cardiology Annual Meeting 2021 Abstracts: Original Research ...
ISIC ISIC
doaj +1 more source
FEBS Letters, EarlyView.Spinal muscular atrophy (SMA) is a genetic disease affecting motor neurons. Individuals with SMA experience mitochondrial dysfunction and oxidative stress. The aim of the study was to investigate the effect of an antioxidant and neuroprotective substance, ergothioneine (ERGO), on an SMNΔ7 mouse model of SMA.
Francesca Cadile +8 more
wiley +1 more source
Proceedings of 2015 Aurora Scientific Day
Journal of Patient-Centered Research and Reviews, 2015 This supplement includes abstracts accepted to the 41st annual Aurora Scientific Day research symposium, held May 20, 2015, in Milwaukee, Wisconsin. Aurora Scientific Day provides a forum for research conducted by residents, fellows, students, teaching ...
Various
doaj +1 more source
Abstracts of the 2022 Canadian Association of Medical Oncologists Annual Scientific Meeting
Current Oncology, 2022 On behalf of the Canadian Association of Medical Oncologists, we are pleased to present the abstracts of the 2022 Annual Meeting. The CAMO Virtual Annual Scientific Meeting (ASM) took place on 28 April 2022.
Doreen Ezeife +5 more
doaj +1 more source
Molecular Oncology, EarlyView.Trastuzumab‐deruxtecan, a HER2‐targeting antibody‐drug conjugate, shows promising antitumor activity in head and neck squamous cell carcinoma with low HER2 expression. In vitro and in vivo studies demonstrated dose‐dependent cell death and tumor growth reduction in low HER2‐expressing cell lines, which correlated with drug accumulation measured using a
Abdullah Bin Naveed +8 more
wiley +1 more source
Genomics‐led approach to drug testing in models of undifferentiated pleomorphic sarcoma
Molecular Oncology, EarlyView.GA text Genomic data from undifferentiated pleomorphic sarcoma patients and preclinical models were used to inform a targeted drug screen. Selected compounds were tested in 2D and 3D cultures of UPS cell lines. A combination of trametinib and infigratinib was synergistic in the majority of UPS cell lines tested, which was further confirmed in an ex ...
Piotr J. Manasterski +19 more
wiley +1 more source
Abstracts of the 44th Annual Scientific Meeting of the Nutrition Society of Australia
Proceedings, 2021 The 44th Annual Scientific Meeting of the Nutrition Society of Australia was held virtually from 3 to 4 December 2020. The theme of the meeting was Nutrition: Adapting to a New World. Abstracts were submitted from 27 countries.
Sandra Iuliano +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Small extracellular vesicles are a promising source of diagnostic molecules. We conducted a comprehensive study, including transcriptome profiling and RT‐qPCR validation on large cohorts of samples. Diagnostic panels enabling sensitive detection of colorectal cancer and precancerous lesions were established. Some molecules were differentially expressed
Petra Vychytilova‐Faltejskova +26 more
wiley +1 more source