Results 1 to 10 of about 14,419 (158)

Biomarkers and Their Possible Functions in the Intestinal Microenvironment of Chagasic Megacolon: An Overview of the (Neuro)inflammatory Process

Journal of Immunology Research, 2021
The association between inflammatory processes and intestinal neuronal destruction during the progression of Chagasic megacolon is well established. However, many other components play essential roles, both in the long-term progression and control of the
José Rodrigues do Carmo Neto, Yarlla Loyane Lira Braga, Arthur Wilson Florêncio da Costa, Fernanda Hélia Lucio, Thais Cardoso do Nascimento, Marlene Antônia dos Reis, Mara Rubia Nunes Celes, Flávia Aparecida de Oliveira, Juliana Reis Machado, Marcos Vinícius da Silva   +9 more
doaj   +2 more sources

Trypanosomiasis-induced megacolon illustrates how myenteric neurons modulate the risk for colon cancer in rats and humans. [PDF]

PLoS Neglected Tropical Diseases, 2015
BACKGROUND:Trypanosomiasis induces a remarkable myenteric neuronal degeneration leading to megacolon. Very little is known about the risk for colon cancer in chagasic megacolon patients.
Vinicius Kannen, Enio C de Oliveira, Bruno Zene Motta, Annuar Jose Chaguri, Mariângela Ottoboni Brunaldi, Sérgio B Garcia   +5 more
doaj   +2 more sources

Megacolon due to Chronic Schistosomiasis: A Case Report and Review of Literature

Case Reports in Surgery, 2019
Although Schistosoma infection in humans commonly involves the intestines, megacolon is a rare finding. We report a 47-year-old patient who was found to have chronic megacolon.
Amer R. Alzahrani, Homoud Alawfi, Sara Almeman, Thamer Altayeb, Hasan M. Al-Dorzi   +4 more
doaj   +2 more sources

Nasogastric Delivery of Fecal Microbiota Transplantation for the Treatment of Fulminant Clostridioides difficile Infection: A Case Report [PDF]

JGH Open
Introduction Clostridioides difficile infection (CDI) is a significant cause of antibiotic‐associated diarrhea with high morbidity and mortality, particularly in cases of fulminant disease. Fecal microbiota transplantation (FMT) has demonstrated efficacy
Amitjeet Singh, Edward Young, Aashish Maurya, Arvind Rajagopalan   +3 more
doaj   +2 more sources

A Case of Toxic Megacolon Caused by Clostridium difficile Infection and Treated with Fecal Microbiota Transplantation

Gut and Liver, 2015
Toxic megacolon is a rare clinical complication of fulminant Clostridium difficile infection. The mortality rate of fulminant C. difficile infection is reported to be as high as 50%.
T. Gweon, K. Lee, Donghoon Kang, Sung Soo Park, K. Kim, Hyeonjin Seong, T. Ban, S. Moon, J. S. Kim, S. Kim   +9 more
doaj   +2 more sources

Idiopathic Megacolon—Short Review

Diagnostics, 2021
Introduction: Idiopathic megacolon (IM) is a rare condition with a more or less known etiology, which involves management challenges, especially therapeutic, and both gastroenterology and surgery services.
A. Constantin, F. Achim, D. Spînu, B. Socea, D. Predescu   +4 more
semanticscholar   +1 more source

Toxic Megacolon Burdened with COVID-19 Coinfection—Worsening of an Unfavorable Diagnosis: A Single-Center Retrospective Study

Life, 2022
Introduction: This study primarily sought to evaluate the risk factors for toxic megacolon development and treatment outcomes in Clostridium difficile-positive COVID-19 patients, secondarily to determining predictors of survival.
Tomáš Řezáč, Dušan Klos, Martin Stašek, Radek Vrba, Pavel Zbořil, Petr Špička   +5 more
doaj   +1 more source

Toxic Megacolon: Background, Pathophysiology, Management Challenges and Solutions

Clinical and Experimental Gastroenterology, 2020
Toxic megacolon (TM) is one of the fatal complications of inflammatory bowel disease (IBD) or any infectious etiology of the colon that is characterized by total or partial nonobstructive colonic dilatation and systemic toxicity.
Jiten Desai, Mohamed Elnaggar, Ahmed A Hanfy, R. Doshi   +3 more
semanticscholar   +1 more source

Toxic megacolon after irrational antibiotic treatment of pregnat patient with Covid 19: Case report [PDF]

Hospital Pharmacology, 2022
Introduction: Optimal management of toxic megacolon as a consequence of Cl. difficile colitis is still matter of controversy, as well as timing of available therapeutic modalities. In this article we report a case of severe C.
Maksić Mladen M., Đokić Anđela Ž., Zdravković Nataša D., Milojković-Kicevska Biljana N., Vojinović Radiša H., Veljković Tijana B., Popović-Matović Svetlana S., Janković Slobodan M.   +7 more
doaj   +1 more source

Chagasic megacolon in Venezuela ‒ case report

Journal of Coloproctology, 2020
Chagasic megacolon is the second most frequent cause of manifestation of the digestive forms of Chagas disease (trypanosoma cruzi parasitosis), characterized by progressive pseudo-occlusive symptoms or chronic constipation, caused by an alteration in the
Victoria Dowling Enez, Carla Izarra Henriquez   +1 more
doaj   +1 more source