Results 51 to 60 of about 9,521 (148)

Adult Onset Hirschsprung's Disease With Overlapping Presentation of Sigmoid Volvulus: Two Case Reports With Literature Review at Tikur Ambessa Specialized Hospital, AAU, Ethiopia

open access: yesClinical Case Reports, Volume 14, Issue 10, October 2026.
ABSTRACT Adult‐onset Hirschsprung's disease (HSD) is uncommon and frequently leads to diagnostic difficulty after infancy. It is a congenital illness that causes intestinal obstruction due to a lack of ganglion cells. Approximately 1 in 5000 live newborns have this illness, and 95% of HSD cases are identified in infants.
Abel shiferaw Tesfaye   +5 more
wiley   +1 more source

Avaliação do processo regenerativo em neurônios do sistema nervoso entérico de pacientes chagásicos portadores de megacólon [PDF]

open access: yes, 2012
Chagas disease is one of the most serious parasitic diseases in Latin America, with social and economic impact that far outweigh the combined effects of other parasitic diseases such as malaria, leishmaniasis and schistosomiasis.
Moreira, Milena Aparecida Dionizio
core   +1 more source

Colonic Dilatation Complicating Acute Severe Ulcerative Colitis Managed Successfully with Accelerated Infliximab Dosing

open access: yesCase Reports in Gastroenterology, 2023
Lately, emerging data suggest an association between the development of inflammatory bowel disease and anti-interleukin-17 therapy. Megacolon is a life-threatening complication of acute severe ulcerative colitis (ASUC), but its treatment has not yet been
Hoang Huu Bui   +3 more
doaj   +1 more source

Tumor Infiltrating Lymphocyte Therapy Combined With PD‐1/LAG‐3 Inhibition in Patients With Recurrent Platinum‐Resistant Ovarian Cancer

open access: yesInternational Journal of Cancer, Volume 159, Issue 7, Page 1735-1749, 1 October 2026.
The detection of tumor‐infiltrating lymphocytes (TILs) is a positive prognostic factor in ovarian cancer. Moreover, TILs are significantly boosted by immunotherapy, though ovarian cancer patients have seen limited benefit from immune therapies. This study investigated the safety and feasibility of TIL therapy combined with PD‐1 and LAG‐3 inhibitors in ...
Tine J. Monberg   +9 more
wiley   +1 more source

A evolução da terapêutica conservadora no tratamento do megacólon tóxico. [PDF]

open access: yes, 2021
Trabalho de Conclusão de Curso (graduação) - UNICEPLAC - Centro Universitário do Planalto Central Apparecido dos Santos, Curso de Medicina, 2021.O Megacólon tóxico (MT) é uma entidade clínica rara com alta morbimortalidade que ocorre como complicação de ...
Lourenço, Juliany Oliveira
core  

Megacolon due to Chronic Schistosomiasis: A Case Report and Review of Literature

open access: yesCase Reports in Surgery, 2019
Although Schistosoma infection in humans commonly involves the intestines, megacolon is a rare finding. We report a 47-year-old patient who was found to have chronic megacolon.
Amer R. Alzahrani   +4 more
doaj   +1 more source

Mucosal‐Associated Invariant T Cells in Health and Disease

open access: yesMedComm, Volume 7, Issue 10, October 2026.
The roles of MAIT cells in health and disease and their therapeutic applications. In healthy individuals, riboflavin metabolites secreted by commensal bacteria at mucosal sites are presented by MR1, leading to the activation of MAIT cells. Activated MAIT cells can maintain the barrier integrity of mucosal tissues in a steady state or migrate to the ...
Yu Zhao   +5 more
wiley   +1 more source

Megacolon tóxico

open access: yesGalicia Clínica, 2019
Mujer de 64 años, con antecedentes de paraplejia postraumática e infecciones urinarias de repetición. Consulta por fiebre de 3 días de evolución y clínica miccional.
Alicia Alvarellos Pérez   +1 more
doaj   +1 more source

Perforated Toxic Megacolon: The Dreaded Complication in IBD

open access: yesWorld Journal of Colorectal Surgery, 2020
Toxic megacolon is a dreaded complication of inflammatory bowel disease. Unfortunately, it is usually diagnosed late and, in cases of perforation, has a high mortality rate and is associated with a poor prognosis.
Kanmani Murugesu   +3 more
doaj   +1 more source

Lowering the C‐Reactive Protein (CRP) Threshold Improves Risk Stratification in Acute Ulcerative Colitis: A Propensity‐Matched Analysis

open access: yesAlimentary Pharmacology &Therapeutics, Volume 64, Issue 7, Page 985-1000, October 2026.
In 503 acute UC admissions, colectomy risk was equivalent between TWC‐positive ASUC and NASUC inpatients after propensity score matching for objective disease severity and treatment exposure; lowering the CRP threshold to ≥ 12 mg/L reclassified 26% of NASUC cases as ASUC and captured 43% of those requiring colectomy within one year, improving ...
Amirah Etchegaray   +8 more
wiley   +1 more source

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