Results 61 to 70 of about 9,521 (148)

Review Article: Immune Effector Cell‐Mediated Enterocolitis Following CAR‐T Cell Therapy—Clinical Features, Pathophysiology and Management

Alimentary Pharmacology &Therapeutics, Volume 64, Issue 8, Page 1046-1057, October 2026.
Immune effector cell‐mediated enterocolitis is an emerging complication of CAR‐T therapy. This review summarizes its epidemiology, pathophysiology, diagnosis, endoscopic and histopathologic features, and evidence‐based management, emphasizing early recognition, multidisciplinary intervention, and step‐up therapy.
John A. Damianos, Yi Lin, Zongming Eric Chen, Kenneth J. C. Lim, Navreet M. Chowla   +4 more
wiley   +1 more source

ABORDAGEM INTERDISCIPLINAR DE CASO DE MEGACÓLON DE DOENÇA DE CHAGAS [PDF]

, 2007
O presente estudo descreve a abordagem terapêutica interdisciplinar em um caso de megacolon na doença de Chagas atendido pelo programa ACHEI da Universidade Estadual de Maringá.
BONANI, Andréa Rosada, GUIMARÃES, Luciana Angélica   +1 more
core   +1 more source

Association of chagasic megacolon and cancer of the colon: case report and review of the literature

Revista da Sociedade Brasileira de Medicina Tropical, 2002
There are few descriptions of association between chagasic megacolon and colon cancer. We report a case of obstructive abdomen caused by adenocarcinoma of the left colon in chagasic megacolon.
Sheila Jorge Adad, Renata Margarida Etchebehere, José Ribamar de Araújo, Andrea Berdu Madureira, Vanessa Guimarães Freitas Lima, Alex Augusto da Silva, Crema Eduardo   +6 more
doaj  

Megacólon chagásico congênito: relato de um caso

Revista da Sociedade Brasileira de Medicina Tropical, 1986
Os autores descrevem o caso de um recém-nascido anencéfalo com oito dias de vida, que à autópsia apresentava grande dilatação do cólon descendente, acompanhada de alterações degenerativas e inflamatórias dos plexos mioentéricos e parasitismo de células ...
Marco Antonio Cardoso de Almeida, Helenemarie Schaer Barbosa   +1 more
doaj   +1 more source

Lymphocyte‐C‐Reactive Protein Ratio as Promising New Marker for Predicting Surgical Site Infection in Children With Ulcerative Colitis

Annals of Gastroenterological Surgery, Volume 10, Issue 5, Page 1586-1593, September 2026.
This study identifies the preoperative lymphocyte‐to–C‐reactive protein ratio (LCR) as a potent and independent biomarker for predicting surgical site infection (SSI) in pediatric patients undergoing major surgery for ulcerative colitis. ROC analysis established an optimal cutoff of 5000 (AUC: 0.80), which demonstrated robust predictive performance ...
Yuhki Koike, Koki Higashi, Yuki Sato, Yuka Nagano, Tadanobu Shimura, Takahito Kitajima, Kohei Matsushita, Yoshiki Okita, Yoshinaga Okugawa, Yuji Toiyama   +9 more
wiley   +1 more source

Profile of interstitial cells of Cajal in a murine model of chagasic megacolon [PDF]

Anais da Academia Brasileira de Ciências
Disorders of gastrointestinal motility are the major physiologic problem in chagasic megacolon. The contraction mechanism is complex and controlled by different cell types such as enteric neurons, smooth muscle, telocytes, and an important pacemaker of ...
MAYRA FERNANDA RICCI, ANA L. MAZZETI, JOANA L. BARBOSA, FABIANA S. MACHADO, MARIA TEREZINHA BAHIA, ROSA MARIA E. ARANTES, SAMANTHA R. SOUZA   +6 more
doaj   +1 more source

Multiomics analyses revealed the roles of the epithelial–mesenchymal transition and novel early candidate diagnostic biomarkers in neonatal necrotising enterocolitis

Clinical and Translational Medicine, Volume 16, Issue 9, September 2026.
In infants with necrotising enterocolitis (NEC), excessive inflammation and epithelial cell death promote the epithelial–mesenchymal transition (EMT), leading to damage to intestinal barriers and the translocation of bacteria and toxins. In addition, inflamed epithelia release cytokines to strengthen the inflammatory response.
Xiao‐Chen Liu, Guo‐Bin Liu, Chen Cheng, Jin Zhu, Fei‐Fan Chen, Ying Ji, Yu‐Ni Zhang, Xiao‐Lin Yan, Qing Wang, Xin‐Yu Li, Qing Ai, Yuan Shi, Yu He   +12 more
wiley   +1 more source

Management of Refractory and Difficult‐To‐Treat Inflammatory Bowel Disease: An Expert Opinion Review

JCC Plus, Volume 1, Issue 5, September 2026.
This expert opinion offers a practical framework for refractory and difficult‐to‐treat IBD: confirm inflammation objectively, distinguish pharmacologic from structural and functional disease, and then escalate. Across ten clinical questions, the evidence is often limited to case series, and the resulting statements are identified as expert opinion ...
Filiz Akyuz, Oguz Kagan Bakkaloglu, Nalan Gulsen Unal, Ismail Hakki Kalkan, Mehmet Arhan, Ibrahim Hatemi, Taylan Kav, Murat Toruner, Hale Akpinar, Ahmet Tezel, Aykut Ferhat Celik   +10 more
wiley   +1 more source

Proposta de classificação do megacólon chagásico através de enema opaco

OBJETIVO: Avaliação de exames radiográficos de portadores de megacólon chagásico, estabelecendo parâmetros que possibilitem uma classificação prática da evolução da doença.
Alcino Lázaro da Silva, Etienne Soares de Miranda, Venício do Amaral Quirino, Robson Tadeu Giacomin   +3 more
core   +1 more source

Surgical treatment of Chagas megacolon. Critical analysis of outcome in operative methods Tratamento cirúrgico do megacólon chagásico análise crítica dos resultados dos métodos operatórios [PDF]

, 2008
PURPOSE: Surgical treatment of chagasic megacolon has suffered innumerable transformations over the years. Poor knowledge of the disease physiopathology is one of the reasons.
José Joaquim Ribeiro da Rocha, GARCIA, Ricardo Luiz Santos, Bruna Meyer R. de Matos, FÉRES, Omar, Garcia,Ricardo Luiz Santos, Ricardo Luiz Santos Garcia, Féres,Omar, Matos,Bruna Meyer R. de, Omar Féres, ROCHA, José Joaquim Ribeiro da, MATOS, Bruna Meyer R. de, Rocha,José Joaquim Ribeiro da   +11 more
core   +1 more source