Results 71 to 80 of about 1,458,362 (221)

Crohn's disease activity index and Vienna classification - Is it worthwhile to calculate before surgery? [PDF]

, 2006
Background: Crohn's disease (CD) patients with increased disease activity may reveal an increased risk for perioperative complications. The `Crohn's disease activity index' (CDAI) and the `Vienna classification' (VC) were developed for standardized ...
A. Beham, Best WR, Best WR, Dirks E, Friedman S, Goebell H, Greenstein AJ, H.J. Schlitt, Heimann TM, K.W. Jauch, Kiran RP, Lichtenstein GR, M. Rentsch, Mekhjian HS, Michelassi F, Murch SH, Otterson MF, Post S, Post S, Post S, Raab Y, Scholmerich J, Shepherd HA, Speranza V, Veloso FT, Wettergren A, Whelan G, Yamamoto T, Yamamoto T, Yamamoto T   +29 more
core   +1 more source

Microbiota‐gut‐brain axis multi‐organ chip construction and applications in drug evaluation

iMetaOmics, Volume 2, Issue 4, December 2025.
Microbiota‐gut‐brain axis multiorgan chip and its applications in drug evaluation. The chip includes essential biological components such as gut microbiota, gut barrier, blood‐brain barrier (BBB), and brain. This integrated platform incorporates neural (blue), endocrine (yellow), immune (pink), and metabolic (green) pathways to investigate the impact ...
Yue Tang, Hewen Chen, Ziyue Zhao, Xuesong Kang, Wenxin Wang, Kun Dai, Yufei Guo, Axin Liang, Aiqin Luo, Zikai Hao   +9 more
wiley   +1 more source

Endometriosis: A Rare Cause of Large Bowel Obstruction. [PDF]

, 2018
Large bowel obstruction can result in significant morbidity and mortality, especially in cases of acute complete obstruction. There are many possible causes, the most common in adults being colorectal cancer.
Alexandrino, G, Carvalho, R, Horta, D, Lourenço, L, Reis, J, Sobrinho, C   +5 more
core   +1 more source

Andrias Davidianus Peptide Hydrogel Enables Sustained SR9011 Release to Promote Efferocytosis and Alleviate Colitis

Small, Volume 21, Issue 50, December 17, 2025.
NR1D1 suppresses epithelial CD47 transcription to promote efferocytosis by macrophages. In UC, NR1D1 expression is diminished, leading to CD47 upregulation, inhibition of apoptotic cell clearance, and exacerbation of intestinal inflammation. Restoring rhythmic NR1D1 activation using SR9011‐loaded bioadhesive hydrogel enhances efferocytosis, improves ...
Yidong Chen, Jiamin Li, Junrong Li, Xiaopeng Zhang, Fang Liu, Qi Yu, Rong Lin, Liangru Zhu   +7 more
wiley   +1 more source

A randomised phase I study of etrolizumab (rhuMAb β7) in moderate to severe ulcerative colitis. [PDF]

, 2013
ObjectiveEtrolizumab (rhuMAb β7, anti-β7, PRO145223) is a humanised monoclonal antibody targeting the β7 subunit of the heterodimeric integrins α4β7 and αEβ7, which are implicated in leucocyte migration and retention in ulcerative colitis (UC).
Baumgart, Daniel C, Bressler, Brian, Danilenko, Dimitri, Egen, Jackson, Fedorak, Richard N, Hommes, Daan W, Keir, Mary, Luca, Diana, Mansfield, John C, O'Byrne, Sharon, Rutgeerts, Paul J, Schreiber, Stefan, Sturm, Andreas, Tang, Meina, Visich, Jennifer, Wei, Xiaohui, Williams, Marna   +16 more
core  

Access to diagnosis and treatment of Chagas disease/infection in endemic and non-endemic countries in the XXI century. [PDF]

, 2007
In this article, Médicos Sin Fronteras (MSF) Spain faces the challenge of selecting, piecing together, and conveying in the clearest possible way, the main lessons learnt over the course of the last seven years in the world of medical care for Chagas ...
Albajar-Vinas, P, Bernal, O, Bulla, D, Morote, S, Villa, L   +4 more
core   +4 more sources

Awareness of Microbiological Safety in Playgrounds Amid Rising Antibiotic Resistance

Environmental Microbiology Reports, Volume 17, Issue 6, December 2025.
Playgrounds are identified as reservoirs for antibiotic‐resistant bacteria, posing a potential public health risk. Despite the existence of safety regulations for playground equipment, microbiological safety is treated superficially. Global strategies, including hygiene practices and antibacterial materials, are needed to reduce the spread of ...
Rafał Łopucki, Marcin Skowronek, Anna Bilokinna, Guillermo Martinez‐de‐Tejada, Ilona Sadok   +4 more
wiley   +1 more source

Shigellosis and AIDS : Report of a case and brief review of the literature [PDF]

, 1989
Contains fulltext : 4491.pdf (publisher's version ) (Open ...
Berkel, M. van, Boers, M., Graaf, P. de, Meer, J.W.M. van der, Peeters, A.J.   +4 more
core   +1 more source

Faecal Microbiota Transplantation plus selected use of antibiotics for severe-complicated Clostridium difficile infection: description of a protocol with high success rate [PDF]

, 2015
Background Severe and severe/complicated Clostridium difficile infection (CDI) can result in ICU admission, sepsis, toxic megacolon and death. In this setting, colectomy is the standard of care but it is associated with a 50% mortality.
Cook, Gwen K., Fischer, Monika, Rex, Douglas K., Robb, Bruce W., Rogers, Nicholas A., Sipe, Brian W., Vuppalanchi, Raj   +6 more
core   +1 more source

Octanoic Acid‐Rich Enteral Nutrition Regulates Intestinal M1/M2 Macrophage Polarization via the PPARγ/STAT‐1/STAT‐6 Pathway to Alleviate Inflammatory Bowel Disease

Food Science &Nutrition, Volume 13, Issue 11, November 2025.
Octanoic acid‐rich enteral nutrition could regulate the M1/M2 polarization of intestinal macrophages and simultaneously repair the intestinal mucosal barrier by activating the PPARγ/STAT‐1/STAT‐6 pathway, thereby significantly alleviating inflammatory bowel disease‐induced intestinal injury.
Liang Xue, Chun Cao
wiley   +1 more source