Management of Refractory and Difficult‐To‐Treat Inflammatory Bowel Disease: An Expert Opinion Review
This expert opinion offers a practical framework for refractory and difficult‐to‐treat IBD: confirm inflammation objectively, distinguish pharmacologic from structural and functional disease, and then escalate. Across ten clinical questions, the evidence is often limited to case series, and the resulting statements are identified as expert opinion ...
Filiz Akyuz +10 more
wiley +1 more source
A patient who survived total colonic ulcerative colitis surinfected by cytomegalovirus complicated by toxic megacolon and disseminated intravascular coagulation [PDF]
peer reviewedThe authors report the case of a patient aged 60-year-old who survived ulcerative colitis complicated by toxic megacolon and disseminated intravascular coagulation.
Detroz, Bernard +6 more
core +1 more source
A Case of Ulcerative Colitis Accompanied by Hemolytic Uremic Syndrome
Hemolytic uremic syndrome (HUS) is a disease presenting with nonimmune hemolytic anemia, renal impairment and low platelet count. Escherichia coli serotype O157:H7 is the most common bacterial strain in typical HUS.
Nilay ŞENGÜL SAMANCI +6 more
doaj
Toxic Megacolon: Background, Pathophysiology, Management Challenges and Solutions
Jiten Desai,1 Mohamed Elnaggar,2 Ahmed A Hanfy,2 Rajkumar Doshi2 1Department of Internal Medicine, Nassau University of Medical Center, East Meadow, NY, USA; 2Department of Internal Medicine, University of Nevada Reno School of Medicine, Reno, NV ...
Desai J, Elnaggar M, Hanfy AA, Doshi R
doaj
Clostridium Difficile Infection Complicated By Toxic Megacolon In Immunocompetent Patient
Toxic megacolon can be a form of severe clinical course of the infection with Clostridium difficile (ICD), life-threatening, requiring a particular course of treatment.
Alina Iancu +5 more
core +1 more source
Regulation of PHOX2B gene expression by the long non‐coding natural antisense RNA PHOX2B‐AS1
PHOX2B is a transcription factor essential for autonomic nervous system development. We identify and characterize PHOX2B‐AS1, a human long non‐coding antisense transcript at the PHOX2B locus, along with its murine counterpart. Our findings reveal bidirectional transcription and reciprocal regulation: PHOX2B activates PHOX2B‐AS1, whereas PHOX2B‐AS1 ...
Simona Di Lascio +12 more
wiley +1 more source
Toxic Megacolon in Granulomatous Colitis [PDF]
Acute, toxic dilatation of the colon in granulomatous colitis occurs more frequently than heretofore reported, and is a more serious complication than its counterpart in ulcerative colitis.
De Marco, V. +2 more
core +1 more source
AIDS related Kaposi's sarcoma presenting as ulcerative colitis and complicated by toxic megacolon
Gastrointestinal Kaposi's sarcoma is a well described and usually asymptomatic manifestation of the acquired immune deficiency syndrome. We report a patient who had extensive colonic Kaposi's sarcoma and presented with an ulcerative colitis like illness.
Biggs, BA +5 more
core +1 more source
ABSTRACT Introduction Combination therapy with immune checkpoint inhibitors (ICIs) has become a standard treatment for metastatic renal cell carcinoma (mRCC). However, ICIs may also cause immune‐related adverse events. We report a case of mRCC that developed fulminant immune‐related enterocolitis.
Kasumi Kanai +9 more
wiley +1 more source
Radiology of acute toxic megacolon
A case is described in which the transition from acute idiopathic ulcerative colitis to acute toxic megacolon was followed radioJogically, and the features which indicate the development of this dangerous complication are identified.S. Afr. Med.
Werbeloff, L +7 more
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