Results 51 to 60 of about 8,119 (216)

Present and past perspectives on Clostridium difficile infection

open access: yesRevista de Gastroenterología de México (English Edition), 2018
Clostridium difficile is a Gram-positive bacillus that has become one of the main hospital-acquired human gastrointestinal infections in recent years.
D.A. Álvarez-Hernández   +5 more
doaj   +1 more source

Management of trypanosomiasis and leishmaniasis [PDF]

open access: yes, 2012
<p>Background: The current treatments for human African trypanosomiasis (HAT), Chagas disease and leishmaniasis (collectively referred to as the kinetoplastid diseases) are far from ideal but, for some, there has been significant recent progress ...
Alsford   +39 more
core   +2 more sources

Systematic Review: The Impact of Geographic Location and Socioeconomic Status on Healthcare Utilisation and Clinical Outcomes in Patients With Inflammatory Bowel Disease (IBD) in the Developed World

open access: yesJCC Plus, Volume 1, Issue 3, May 2026.
ABSTRACT Background Inflammatory bowel diseases (IBD) are a group of chronic inflammatory conditions affecting the gastrointestinal tract, which requires life‐long management. Healthcare inequalities in IBD are a key factor influencing disease outcomes. Aim This review aimed to describe the impact of geographical location (urban vs.
George Tambakis   +6 more
wiley   +1 more source

Risk for Clostridium difficile infection after allogeneic hematopoietic cell transplant remains elevated in the postengraftment period [PDF]

open access: yes, 2017
BACKGROUND: Clostridium difficile infection (CDI) is a frequent cause of diarrhea among allogeneic hematopoietic cell transplant (HCT) recipients. It is unknown whether risk factors for CDI vary by time posttransplant.
Bommarito, Kerry M   +8 more
core   +2 more sources

Outcomes of Clostridium difficile Infection in Patients With Idiopathic Pulmonary Fibrosis: Analysis of the Nationwide Inpatient Sample, 2016–2020

open access: yesJGH Open, Volume 10, Issue 5, May 2026.
ABSTRACT Background Idiopathic pulmonary fibrosis (IPF) is a progressive lung disease with poor prognosis. Patients with IPF are frequently exposed to risk factors for Clostridium difficile infection (CDI), such as advanced age, antibiotic use, and gastric acid suppression.
Chun Ho Szeto   +6 more
wiley   +1 more source

A randomised phase I study of etrolizumab (rhuMAb β7) in moderate to severe ulcerative colitis. [PDF]

open access: yes, 2013
ObjectiveEtrolizumab (rhuMAb β7, anti-β7, PRO145223) is a humanised monoclonal antibody targeting the β7 subunit of the heterodimeric integrins α4β7 and αEβ7, which are implicated in leucocyte migration and retention in ulcerative colitis (UC).
Baumgart, Daniel C   +16 more
core  

A tetraspecific VHH-based neutralizing antibody modifies disease outcome in three animal models of Clostridium difficile infection [PDF]

open access: yes, 2016
Clostridium difficile infection (CDI), a leading cause of nosocomial infection, is a serious disease in North America, Europe, and Asia. CDI varies greatly from asymptomatic carriage to life-threatening diarrhea, toxic megacolon, and toxemia.
Beamer, Gillian   +12 more
core   +2 more sources

First Isolation of Yersinia enterocolitica From a Sea Turtle: A Case Report in Caretta caretta

open access: yesVeterinary Medicine and Science, Volume 12, Issue 3, May 2026.
1. First isolation of Yersinia enterocolitica, a zoonotic bacterium, in a loggerhead sea turtle (Caretta caretta), identifying it as the likely cause of severe colitis, hepatitis, and fatal sepsis. 2. The findings highlight that sea turtles and the marine environment can act as reservoirs for Y. enterocolitica: this poses a “One Health” threat. 3.
Giorgia Schirò   +8 more
wiley   +1 more source

Ionomycin Exhibits Potent and Selective Bactericidal Activity Against Clostridioides difficile Through Calcium‐Dependent Membrane Disruption

open access: yesMicrobiologyOpen, Volume 15, Issue 2, April 2026.
Ionomycin exhibits potent and selective bactericidal activity against Clostridioides difficile, rapidly reducing vegetative cells, toxin production, sporulation, and spore germination while sparing representative gut microbiota. Its activity is calcium‐dependent and mediated through disruption of bacterial membrane potential, highlighting ionomycin as ...
Ahmed A. Abouelkhair   +2 more
wiley   +1 more source

A Rare Presentation of Crohn's Disease [PDF]

open access: yes, 2008
Free peritoneal perforation is a rare complication of Crohn's disease with a report of only 100 cases in the literature. It needs an emergency exploration and an unaware general surgeon is confounded in intraoperative decision-making.
Bhat, Sriram M   +4 more
core   +1 more source

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