Results 51 to 60 of about 8,119 (216)
Present and past perspectives on Clostridium difficile infection
Clostridium difficile is a Gram-positive bacillus that has become one of the main hospital-acquired human gastrointestinal infections in recent years.
D.A. Álvarez-Hernández +5 more
doaj +1 more source
Management of trypanosomiasis and leishmaniasis [PDF]
<p>Background: The current treatments for human African trypanosomiasis (HAT), Chagas disease and leishmaniasis (collectively referred to as the kinetoplastid diseases) are far from ideal but, for some, there has been significant recent progress ...
Alsford +39 more
core +2 more sources
ABSTRACT Background Inflammatory bowel diseases (IBD) are a group of chronic inflammatory conditions affecting the gastrointestinal tract, which requires life‐long management. Healthcare inequalities in IBD are a key factor influencing disease outcomes. Aim This review aimed to describe the impact of geographical location (urban vs.
George Tambakis +6 more
wiley +1 more source
Risk for Clostridium difficile infection after allogeneic hematopoietic cell transplant remains elevated in the postengraftment period [PDF]
BACKGROUND: Clostridium difficile infection (CDI) is a frequent cause of diarrhea among allogeneic hematopoietic cell transplant (HCT) recipients. It is unknown whether risk factors for CDI vary by time posttransplant.
Bommarito, Kerry M +8 more
core +2 more sources
ABSTRACT Background Idiopathic pulmonary fibrosis (IPF) is a progressive lung disease with poor prognosis. Patients with IPF are frequently exposed to risk factors for Clostridium difficile infection (CDI), such as advanced age, antibiotic use, and gastric acid suppression.
Chun Ho Szeto +6 more
wiley +1 more source
A randomised phase I study of etrolizumab (rhuMAb β7) in moderate to severe ulcerative colitis. [PDF]
ObjectiveEtrolizumab (rhuMAb β7, anti-β7, PRO145223) is a humanised monoclonal antibody targeting the β7 subunit of the heterodimeric integrins α4β7 and αEβ7, which are implicated in leucocyte migration and retention in ulcerative colitis (UC).
Baumgart, Daniel C +16 more
core
A tetraspecific VHH-based neutralizing antibody modifies disease outcome in three animal models of Clostridium difficile infection [PDF]
Clostridium difficile infection (CDI), a leading cause of nosocomial infection, is a serious disease in North America, Europe, and Asia. CDI varies greatly from asymptomatic carriage to life-threatening diarrhea, toxic megacolon, and toxemia.
Beamer, Gillian +12 more
core +2 more sources
First Isolation of Yersinia enterocolitica From a Sea Turtle: A Case Report in Caretta caretta
1. First isolation of Yersinia enterocolitica, a zoonotic bacterium, in a loggerhead sea turtle (Caretta caretta), identifying it as the likely cause of severe colitis, hepatitis, and fatal sepsis. 2. The findings highlight that sea turtles and the marine environment can act as reservoirs for Y. enterocolitica: this poses a “One Health” threat. 3.
Giorgia Schirò +8 more
wiley +1 more source
Ionomycin exhibits potent and selective bactericidal activity against Clostridioides difficile, rapidly reducing vegetative cells, toxin production, sporulation, and spore germination while sparing representative gut microbiota. Its activity is calcium‐dependent and mediated through disruption of bacterial membrane potential, highlighting ionomycin as ...
Ahmed A. Abouelkhair +2 more
wiley +1 more source
A Rare Presentation of Crohn's Disease [PDF]
Free peritoneal perforation is a rare complication of Crohn's disease with a report of only 100 cases in the literature. It needs an emergency exploration and an unaware general surgeon is confounded in intraoperative decision-making.
Bhat, Sriram M +4 more
core +1 more source

