Results 41 to 50 of about 5,045 (167)

Long‐term outcomes of children with ulcerative colitis after acute severe colitis: A GETAID pédiatrique multicenter study

Journal of Pediatric Gastroenterology and Nutrition, Volume 83, Issue 1, Page 117-126, July 2026.
Abstract Objectives Acute severe colitis (ASC) is a frequent and severe complication of ulcerative colitis (UC) with a high risk of colectomy. Effects of immunosuppressants and anti–tumor necrosis factor (anti‐TNF) agents on the risk of colectomy remain debated. We wished to study the evolution of French pediatric‐onset UC patients after ASC.
Manon Cochet, Agathe Beauvais, Frank Ruemmele, Raphael Enaud, Thierry Lamireau, Rémi Duclaux‐Loras, Claire Dupont, Stéphanie Willot, Laure Bridoux‐Henno, Georges Dimitrov, Julie Lemale, Vincent Guinard‐Samuel, Valérie Bertrand, Anne Breton, Christine Martinez Vinson, Stéphanie Coopman, Delphine Ley, Bénédicte Pigneur, and the Groupe d'Etudes Thérapeutiques des Affections Inflammatoires du tube Digestif (GETAID) pédiatrique   +18 more
wiley   +1 more source

Regulation of PHOX2B gene expression by the long non‐coding natural antisense RNA PHOX2B‐AS1

The FEBS Journal, Volume 293, Issue 12, Page 3502-3527, June 2026.
PHOX2B is a transcription factor essential for autonomic nervous system development. We identify and characterize PHOX2B‐AS1, a human long non‐coding antisense transcript at the PHOX2B locus, along with its murine counterpart. Our findings reveal bidirectional transcription and reciprocal regulation: PHOX2B activates PHOX2B‐AS1, whereas PHOX2B‐AS1 ...
Simona Di Lascio, Ana Lucia Cuadros Gamboa, Martina Bertocchi, Filippo Chiesa, Francesca Cargnin, Ettore Mosca, Paride Pelucchi, Viviana Tritto, Stefania Corti, Isabella Ceccherini, Paola Riva, Roberta Benfante, Diego Fornasari   +12 more
wiley   +1 more source

A Case of Ulcerative Colitis Accompanied by Hemolytic Uremic Syndrome

Turkish Journal of Nephrology, 2019
Hemolytic uremic syndrome (HUS) is a disease presenting with nonimmune hemolytic anemia, renal impairment and low platelet count. Escherichia coli serotype O157:H7 is the most common bacterial strain in typical HUS.
Nilay ŞENGÜL SAMANCI, Egemen CEBECİ, Abdülkadir ERGEN, Şule POTUROĞLU, Mesut AYER, Şeref ÖNCÜ, Savaş ÖZTÜRK   +6 more
doaj  

Toxic Megacolon: Background, Pathophysiology, Management Challenges and Solutions

Clinical and Experimental Gastroenterology, 2020
Jiten Desai,1 Mohamed Elnaggar,2 Ahmed A Hanfy,2 Rajkumar Doshi2 1Department of Internal Medicine, Nassau University of Medical Center, East Meadow, NY, USA; 2Department of Internal Medicine, University of Nevada Reno School of Medicine, Reno, NV ...
Desai J, Elnaggar M, Hanfy AA, Doshi R
doaj  

A Case of Fulminant Immune‐Related Enterocolitis During Immune Checkpoint Inhibitor Therapy for Metastatic Renal Cell Carcinoma

IJU Case Reports, Volume 9, Issue 3, May 2026.
ABSTRACT Introduction Combination therapy with immune checkpoint inhibitors (ICIs) has become a standard treatment for metastatic renal cell carcinoma (mRCC). However, ICIs may also cause immune‐related adverse events. We report a case of mRCC that developed fulminant immune‐related enterocolitis.
Kasumi Kanai, Takayuki Sumiyoshi, Hiroki Kitamoto, Yuki Teramoto, Yuta Mine, Jin Kono, Kimihiko Masui, Takayuki Goto, Ryoichi Saito, Takashi Kobayashi   +9 more
wiley   +1 more source

FROG (Frequency Rates, mOrbidities and timinGs) of Surgical Interventions for UC: A Protocol for an International, Multi‐Centre, Retrospective Cohort Study on Frequency Rates, Morbidities and Timings of Surgical Interventions for Ulcerative Colitis

JCC Plus, Volume 1, Issue 3, May 2026.
ABSTRACT Background The surgical journey of patients diagnosed with ulcerative colitis (UC) typically begins with an index colectomy, which may be followed by restorative procedures or further operations due to complications. Variation in surgical strategies exists, impacting patient outcomes.
Orestis Argyriou, Itai Ghersin, Guy Worley, Phil Tozer, Ailsa Hart, Kapil Sahnan   +5 more
wiley   +1 more source

Toxic Megacolon – the Complication of an Infection with Clostridium difficile after an Odontogenic Abscess. Case Presentation

Journal of Interdisciplinary Medicine, 2019
Background:Clostridium difficile (CD) is the major cause of nosocomial antibiotic-associated infections, having as main manifestation diarrhea and life-threatening inflammation of the colon.
Suciu Nicolae, Benedek Zalán, Sorlea Sorin, Coroș Marius Florin   +3 more
doaj   +1 more source

Inflammatory Bowel Diseases: the Surgical Perspective [PDF]

Modern Medicine, 2019
Inflammatory bowel diseases (IBD), namely Crohn’s disease and ulcerative colitis, are relatively rare diseases in our country, known as a low prevalence geographic region.
SOCEA Bogdan, DUMITRESCU Dan, BRATU Ovidiu Gabriel , CARAP Alexandru Constantin, BADIU Dumitru Cristinel, BOLOCAN Alexandra, PADURARU Dan Nicolae, MISCHIANU Dan, CONSTANTIN Vlad Denis   +8 more
doaj   +1 more source

Systematic Review: The Impact of Geographic Location and Socioeconomic Status on Healthcare Utilisation and Clinical Outcomes in Patients With Inflammatory Bowel Disease (IBD) in the Developed World

JCC Plus, Volume 1, Issue 3, May 2026.
ABSTRACT Background Inflammatory bowel diseases (IBD) are a group of chronic inflammatory conditions affecting the gastrointestinal tract, which requires life‐long management. Healthcare inequalities in IBD are a key factor influencing disease outcomes. Aim This review aimed to describe the impact of geographical location (urban vs.
George Tambakis, Lei Lin, Rina Kumar, Jennifer Phillips, Anthony Croft, Graham Radford‐Smith, Gareth J. Walker   +6 more
wiley   +1 more source

Pseudomembranous colitis and toxic megacolon due to C. difficile in an inpatient hospitalized for home accident

Clinical Management Issues, 2015
Clostridium difficile infection (CDI) is the main cause of hospital-acquired diarrhea. It can result in symptoms ranging from moderate diarrhea to pseudomembranous colitis.
Piergiorgio Chiriacò
doaj   +1 more source