Results 31 to 40 of about 5,495 (201)

MANAGEMENT OF TOXIC MEGACOLON

, 2019
Introduction: Toxic megacolon is differentiated from different types of colonic expansion, for example, Ogilvie syndrome and Hirschsprung disease by the extra presence of systemic toxicity and the incendiary or irresistible etiology of the hidden disease.
Ahmed Anis Abdullah, Mohammed Jamal Goname, Sultan Ashraf Othman, Fahdah Khaled musallam, Asaad saleh radwan, Muayyad Abdullah Abualjadayel, SALIM AHMED ALAZMI, Hattan Saad Alshehri, Zainab Salman Al Shuhayb, Eman ahmed alabdrabalrasol
core   +1 more source

Infliximab in Crohn's disease-associated toxic megacolon

, 2012
Item does not contain fulltextRefractory medical treatment of Crohn disease-associated toxic megacolon usually requires surgery, which carries substantial morbidity and mortality.
Geenen, E.J.M. van, van Geenen, E.M., Erwin-Jan M. van Geenen, Sachar, D.B., David B. Sachar   +4 more
core   +1 more source

Campylobacter colitis: Rare cause of toxic megacolon

, 2016
IntroductionCampylobacter is the leading cause of bacterial diarrhoeal illness worldwide. Toxic megacolon is a rare but potentially devastating complication.Presentation of caseA 55year old female with liver cirrhosis, alcoholism and hepatitis C ...
Kwok, Michael, Maurice, Andrew, Lisec, Carl, Brown, Jason   +3 more
core   +1 more source

In-hospital mortality for toxic megacolon

, 2018
In-hospital mortality for toxic ...
Ciccocioppo, Rachele, Corazza, Gino Roberto   +1 more
core   +1 more source

Colitis ulcerativa fulminante complicada con megacolon tóxico

, 2021
Presentamos un caso de abdomen agudo secundario a megacolon tóxico perforado como debut de colitis ulcerativa que requirió múltiples intervenciones quirúrgicas y estancia prolongada en la unidad de cuidados intensivos.
Meléndez Albarracín , Julián David, Blanco Pertúz , Paola María, Gustavo Adolfo Domínguez Ramírez, María del Socorro Alzamora Acosta, Alzamora Acosta, María del Socorro, Paola María Blanco Pertúz, Julián David Meléndez Albarracín, Gelca Patricia Danies Diaz, Domínguez Ramírez , Gustavo Adolfo, Danies Diaz, Gelca Patricia   +9 more
core   +1 more source

Severe Clostridium difficile infections in intensive care units: Diverse clinical presentations

Journal of Microbiology, Immunology and Infection, 2021
Background: Clostridium difficile infections (CDIs) cause significant mortality and morbidity. Critically ill patients are susceptible to CDIs and tend to have severe CDIs, and their clinical presentations are not merely diarrhea.
Jen-Chieh Lee, Yuan-Pin Hung, Bo-Yang Tsai, Pei-Jane Tsai, Wen-Chien Ko   +4 more
doaj   +1 more source

Therapeutic drug monitoring of antimicrobials in a paediatric setting: A retrospective single‐centre study

British Journal of Clinical Pharmacology, EarlyView.
Aims Paediatric pharmacokinetics differ significantly from adults due to age‐related physiological changes, necessitating precise dose adjustments. However, data on therapeutic drug monitoring (TDM) implementation in paediatric setting remain limited.
Gianluca Gazzaniga, Stefano Agliardi, Riccardo Giossi, Alice Schianchi, Alessandra Romandini, Thomas Virdis, Silvia Nerini Molteni, Maria Luisa De Angelis, Stefania Paccagnini, Cecilia Gechtman, Alice Proto, Marco Fossati, Silvia Oliveri, Giulia Angela Pattarino, Elena Altieri, Agnese Graziosi, Arianna Pani, Romano Danesi, Stefano Martinelli, Costantino De Giacomo, Francesco Scaglione   +20 more
wiley   +1 more source

Tumor Infiltrating Lymphocyte Therapy Combined With PD‐1/LAG‐3 Inhibition in Patients With Recurrent Platinum‐Resistant Ovarian Cancer

International Journal of Cancer, EarlyView.
The detection of tumor‐infiltrating lymphocytes (TILs) is a positive prognostic factor in ovarian cancer. Moreover, TILs are significantly boosted by immunotherapy, though ovarian cancer patients have seen limited benefit from immune therapies. This study investigated the safety and feasibility of TIL therapy combined with PD‐1 and LAG‐3 inhibitors in ...
Tine J. Monberg, Cathrine L. Lorentzen, Marie C. W. Westergaard, Trine Z. Iversen, Troels H. Borch, Marco Donia, Sigrid M. Mannering, Stine E. W. Banke, Özcan Met, Inge Marie Svane   +9 more
wiley   +1 more source

Long‐term outcomes of children with ulcerative colitis after acute severe colitis: A GETAID pédiatrique multicenter study

Journal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Objectives Acute severe colitis (ASC) is a frequent and severe complication of ulcerative colitis (UC) with a high risk of colectomy. Effects of immunosuppressants and anti–tumor necrosis factor (anti‐TNF) agents on the risk of colectomy remain debated. We wished to study the evolution of French pediatric‐onset UC patients after ASC.
Manon Cochet, Agathe Beauvais, Frank Ruemmele, Raphael Enaud, Thierry Lamireau, Rémi Duclaux‐Loras, Claire Dupont, Stéphanie Willot, Laure Bridoux‐Henno, Georges Dimitrov, Julie Lemale, Vincent Guinard‐Samuel, Valérie Bertrand, Anne Breton, Christine Martinez Vinson, Stéphanie Coopman, Delphine Ley, Bénédicte Pigneur, and the Groupe d'Etudes Thérapeutiques des Affections Inflammatoires du tube Digestif (GETAID) pédiatrique   +18 more
wiley   +1 more source

Toxic Megacolon – A Three Case Presentation

, 2017
Introduction: Toxic megacolon is a life-threatening disease and is one of the most serious complications of Clostridium difficile infection (CDI), usually needing prompt surgical intervention. Early diagnosis and adequate medical treatment are mandatory.
Sorin Rugina, Irina Magdalena Dumitru, Eugen Dumitru, Liliana Ana Tuta   +3 more
core   +1 more source