Results 61 to 70 of about 22,318 (247)

Regulation of PHOX2B gene expression by the long non‐coding natural antisense RNA PHOX2B‐AS1

The FEBS Journal, EarlyView.
PHOX2B is a transcription factor essential for autonomic nervous system development. We identify and characterize PHOX2B‐AS1, a human long non‐coding antisense transcript at the PHOX2B locus, along with its murine counterpart. Our findings reveal bidirectional transcription and reciprocal regulation: PHOX2B activates PHOX2B‐AS1, whereas PHOX2B‐AS1 ...
Simona Di Lascio, Ana Lucia Cuadros Gamboa, Martina Bertocchi, Filippo Chiesa, Francesca Cargnin, Ettore Mosca, Paride Pelucchi, Viviana Tritto, Stefania Corti, Isabella Ceccherini, Paola Riva, Roberta Benfante, Diego Fornasari   +12 more
wiley   +1 more source

William Arbuthnot Lane (1856-1943): Surgical Innovator and His Theory of Autointoxication. [PDF]

, 2017
William Arbuthnot Lane contributed to the advancement of many fields of orthopedics, otolaryngology, and general surgery. He is credited for his no-touch technique and the invention of long-handled instruments, some of which are still in use today, to ...
Cowan, Scott W., Morris, Mackenzie, Phillips, Benjamin, Price, Thea, Yeo, Charles J.   +4 more
core   +1 more source

Nonobstructing Colonic Dilatation and Colon Perforations Following Renal Transplantation [PDF]

, 1990
Nonobstructing colonic dilatation has not been commonly reported following renal transplantation, and colon perforations carry a high morbidity and mortality in this population.
Hakala, TR, Koneru, B, O'hair, DP, Selby, R, Starzl, TE, Tzakis, AG   +5 more
core   +1 more source

Ionomycin Exhibits Potent and Selective Bactericidal Activity Against Clostridioides difficile Through Calcium‐Dependent Membrane Disruption

MicrobiologyOpen, Volume 15, Issue 2, April 2026.
Ionomycin exhibits potent and selective bactericidal activity against Clostridioides difficile, rapidly reducing vegetative cells, toxin production, sporulation, and spore germination while sparing representative gut microbiota. Its activity is calcium‐dependent and mediated through disruption of bacterial membrane potential, highlighting ionomycin as ...
Ahmed A. Abouelkhair, Nader S. Abutaleb, Mohamed N. Seleem   +2 more
wiley   +1 more source

Local diagnostic reference levels for pediatric fluoroscopy in a Brazilian tertiary referral center: A weight‑based analysis

Journal of Applied Clinical Medical Physics, Volume 27, Issue 3, March 2026.
Abstract Purpose To establish the first DRLs for contrast‐enhanced diagnostic pediatric fluoroscopic procedures in Brazil, stratified by body weight, based on data collected in a single tertiary referral public hospital of Rio de Janeiro city. Methods This descriptive, cross‐sectional study included 928 diagnostic fluoroscopy examinations performed in ...
Claudia M. C. Ribeiro, Tainá O. Chaves, Marcos Decnop, Renato Gonçalves de Mendonça, Margareth Catoia Varela, Cesar Augusto Viana de Araujo, Saint Clair Gomes Junior   +6 more
wiley   +1 more source

Performance of prognostic index in severe Clostridium difficile-associated infection. Retrospective analysis in a university hospital [PDF]

, 2014
Indexación: ScieloIntroducción: Por consenso, la infección asociada a Clostridium difficile (IACD) grave es aquella que resulta en hospitalización en unidad de cuidados intensivos, colectomía o muerte dentro de 30 días. Múltiples índices pronósticos (IP)
Agüero Luengo, Carlos, Barra-Carrasco, Jonathan, Guzmán-Durán, Ana M., Hernández-Rocha, Cristian, Ibáñez Lazo, Patricio, Inostroza Levy, Gonzalo, Molina Pezoa, M. Elena, Paredes-Sabja, Daniel, Plaza-Garrido, Ángela, Tejos Sufan, Rodrigo, Álvarez-Lobos, Manuel   +10 more
core   +1 more source

HSV1/2 Genital Infection in Mice Cause Reversible Delayed Gastrointestinal Transit: A Model for Enteric Myopathy

Frontiers in Medicine, 2018
In an interesting investigation by Khoury-Hanold et al. (1), genital infection of mice with herpes simplex virus 1 (HSV1) were reported to cause multiple pelvic organ involvement and obstruction.
Arun Chaudhury, Vijaya Sena Reddy Dendi, Mousumi Chaudhury, Astha Jain, Madhukar Reddy Kasarla, Kiran Panuganti, Gaurav Jain, Abhijit Ramanujam, Bhavin Rena, Sudheer Reddy Koyagura, Sumit Fogla, Sunil Kumar, Nawal Singh Shekhawat, Srinivas Maddur, Srinivas Maddur   +14 more
doaj   +1 more source

Colitis ulcerativa fulminante complicada con megacolon tóxico

Repertorio de Medicina y Cirugía, 2021
Presentamos un caso de abdomen agudo secundario a megacolon tóxico perforado como debut de colitis ulcerativa que requirió múltiples intervenciones quirúrgicas y estancia prolongada en la unidad de cuidados intensivos.
Gelca Patricia Danies Diaz, María del Socorro Alzamora Acosta, Gustavo Adolfo Domínguez Ramírez , Paola María Blanco Pertúz , Julián David Meléndez Albarracín   +4 more
doaj   +1 more source

Discovery of a Dual‐Target DNAzyme for Clostridioides difficile and Listeria monocytogenes Diagnostics

ChemistryEurope, Volume 4, Issue 3, March 2026.
A newly discovered fluorogenic DNAzyme, RFD‐CD3, enables rapid and sensitive detection of Clostridioides difficile and—unexpectedly—Listeria monocytogenes, making it the first dual‐responsive DNAzyme for two unrelated bacterial pathogens. Its strong catalytic efficiency, pH‐tolerant activity, and modular trans‐acting design position it as a promising ...
Soyeon Lee, Dingran Chang, Jimmy Gu, Bruno J. Salena, Yingfu Li   +4 more
wiley   +1 more source

Profile of interstitial cells of Cajal in a murine model of chagasic megacolon [PDF]

Anais da Academia Brasileira de Ciências
Disorders of gastrointestinal motility are the major physiologic problem in chagasic megacolon. The contraction mechanism is complex and controlled by different cell types such as enteric neurons, smooth muscle, telocytes, and an important pacemaker of ...
MAYRA FERNANDA RICCI, ANA L. MAZZETI, JOANA L. BARBOSA, FABIANA S. MACHADO, MARIA TEREZINHA BAHIA, ROSA MARIA E. ARANTES, SAMANTHA R. SOUZA   +6 more
doaj   +1 more source