Results 41 to 50 of about 11,309 (161)

Cortisol concentrations in hair are biomarkers of health status and seasonal change, but not urbanisation, in wolves

open access: yesWildlife Biology, EarlyView.
Wolves have reclaimed much of their former range in Europe, including areas with a high human footprint, yet the physiological impacts of human‐associated stressors remain poorly understood. We first examined methodological factors affecting hair cortisol concentrations (HCC) in wolves by using a ‘shave/re‐shave' design to assess hair growth rate and ...
Gwendolyn Wirobski   +15 more
wiley   +1 more source

Enfermedad de Chagas y sus manifestaciones neurológicas

open access: yesActa Neurológica Colombiana, 2021
La enfermedad de chagas (tripanosomiasis americana) es una zoonosis potencialmente mortal causada por el parásito Trypanosoma cruzi, transmitido por vectores encontrados principalmente en territorio latinoamericano, aunque tiene otras vías de ...
Daniela Duque Montoya   +1 more
doaj   +1 more source

Tigecycline combination therapy for fulminant Clostridioides difficile infection: an Australian experience

open access: yesInternal Medicine Journal, EarlyView.
Abstract Background Recent European Society of Clinical Microbiology and Infection and Australasian Society of Infectious Diseases Clostridioides difficile infection (CDI) management guidelines endorse the addition of intravenous tigecycline in patients who are progressing to fulminant infection.
Emma Bishop   +5 more
wiley   +1 more source

First reported case of afatinib-associated toxic megacolon [PDF]

open access: yes, 2018
We report the first case of toxic megacolon associated with afatinib use, which is a potentially fatal complication, with risks of colonic perforation. In this case, the condition improved on stopping afatnib. Clinicians need to be alert of this rare but
Lam, DCL, Kwok, WC, Tam, TCC
core   +1 more source

Third Space Endoscopic Therapies for Benign Motility Disorders: A Narrative Review

open access: yesDEN Open, Volume 7, Issue 1, April 2027.
ABSTRACT Objectives To review the evidence base, evolution, outcomes, adverse events (AEs), and management for third‐space endoscopy (TSE) procedures for management of benign motility disorders. Methods This review examines TSE procedures for motility disorders, reviewing the current available techniques, success, outcomes, and long‐term outcomes from ...
Sanjana Bhagwat, Amol Bapaye
wiley   +1 more source

HSV1/2 Genital Infection in Mice Cause Reversible Delayed Gastrointestinal Transit: A Model for Enteric Myopathy

open access: yesFrontiers in Medicine, 2018
In an interesting investigation by Khoury-Hanold et al. (1), genital infection of mice with herpes simplex virus 1 (HSV1) were reported to cause multiple pelvic organ involvement and obstruction.
Arun Chaudhury   +14 more
doaj   +1 more source

Tumor Infiltrating Lymphocyte Therapy Combined With PD‐1/LAG‐3 Inhibition in Patients With Recurrent Platinum‐Resistant Ovarian Cancer

open access: yesInternational Journal of Cancer, Volume 159, Issue 7, Page 1735-1749, 1 October 2026.
The detection of tumor‐infiltrating lymphocytes (TILs) is a positive prognostic factor in ovarian cancer. Moreover, TILs are significantly boosted by immunotherapy, though ovarian cancer patients have seen limited benefit from immune therapies. This study investigated the safety and feasibility of TIL therapy combined with PD‐1 and LAG‐3 inhibitors in ...
Tine J. Monberg   +9 more
wiley   +1 more source

Profile of interstitial cells of Cajal in a murine model of chagasic megacolon [PDF]

open access: yesAnais da Academia Brasileira de Ciências
Disorders of gastrointestinal motility are the major physiologic problem in chagasic megacolon. The contraction mechanism is complex and controlled by different cell types such as enteric neurons, smooth muscle, telocytes, and an important pacemaker of ...
MAYRA FERNANDA RICCI   +6 more
doaj   +1 more source

Mucosal‐Associated Invariant T Cells in Health and Disease

open access: yesMedComm, Volume 7, Issue 10, October 2026.
The roles of MAIT cells in health and disease and their therapeutic applications. In healthy individuals, riboflavin metabolites secreted by commensal bacteria at mucosal sites are presented by MR1, leading to the activation of MAIT cells. Activated MAIT cells can maintain the barrier integrity of mucosal tissues in a steady state or migrate to the ...
Yu Zhao   +5 more
wiley   +1 more source

Clinical efficacy of laparoscopic subtotal colectomy in adult megacolon

open access: yesZhongguo linchuang yanjiu, 2023
ObjectiveTo observe the clinical efficacy and safety of laparoscopic subtotal colectomy + loop colostomy in adult patients with megacolon. MethodsRetrospective analysis was performed on the clinical data of 22 adult megacolon patients treated by ...
WANG Qifei   +5 more
doaj  

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