Results 61 to 70 of about 16,608 (207)

Electro‐clinical features of Mowat–Wilson syndrome: A retrospective study of 31 children in mainland China

open access: yesEpileptic Disorders, Volume 28, Issue 2, Page 344-358, April 2026.
Abstract Objective To summarize the electro‐clinical and genetic characteristics of children with Mowat–Wilson syndrome (MWS). Methods This study is a hospital‐based case series analyzing clinical data from 31 pediatric patients with MWS and epilepsy treated at Peking University First Hospital between June 2020 and December 2024.
Yi Ju, Tao‐yun Ji
wiley   +1 more source

Genetic background-dependent abnormalities of the enteric nervous system and intestinal function in Kif26a-deficient mice

open access: yesScientific Reports, 2021
The Kif26a protein-coding gene has been identified as a negative regulator of the GDNF-Ret signaling pathway in enteric neurons. The aim of this study was to investigate the influence of genetic background on the phenotype of Kif26a-deficient (KO ...
Yukiko Ohara   +11 more
doaj   +1 more source

Controlling clostridium difficile [PDF]

open access: yes, 2013
Clostridium difficile infection causes colitis and is closely associated with the use of antimicrobials, probably due to disruption of the normal bowel flora.
Hajkowicz, Krispin, McFarlane, Mark
core   +1 more source

Ionomycin Exhibits Potent and Selective Bactericidal Activity Against Clostridioides difficile Through Calcium‐Dependent Membrane Disruption

open access: yesMicrobiologyOpen, Volume 15, Issue 2, April 2026.
Ionomycin exhibits potent and selective bactericidal activity against Clostridioides difficile, rapidly reducing vegetative cells, toxin production, sporulation, and spore germination while sparing representative gut microbiota. Its activity is calcium‐dependent and mediated through disruption of bacterial membrane potential, highlighting ionomycin as ...
Ahmed A. Abouelkhair   +2 more
wiley   +1 more source

Association of chagasic megacolon and cancer of the colon: case report and review of the literature

open access: yesRevista da Sociedade Brasileira de Medicina Tropical, 2002
There are few descriptions of association between chagasic megacolon and colon cancer. We report a case of obstructive abdomen caused by adenocarcinoma of the left colon in chagasic megacolon.
Sheila Jorge Adad   +6 more
doaj  

An Adolescent Case of Ulcerative Colitis Complicated by Toxic Megacolon

open access: yesCase Reports in Gastroenterology
Introduction: Toxic megacolon is a serious complication of ulcerative colitis (UC), characterized by marked colonic dilatation, abnormal bowel function, and systemic toxicity.
Masaki Kato   +16 more
doaj   +1 more source

Foxf1 and Foxf2 control murine gut development by limiting mesenchymal Wnt signaling and promoting extracellular matrix production [PDF]

open access: yes, 2006
Development of the vertebrate gut is controlled by paracrine crosstalk between the endodermal epithelium and the associated splanchnic mesoderm. In the adult, the same types of signals control epithelial proliferation and survival, which account for the ...
Astorga (Johansson), Jeanette   +6 more
core   +2 more sources

Local diagnostic reference levels for pediatric fluoroscopy in a Brazilian tertiary referral center: A weight‑based analysis

open access: yesJournal of Applied Clinical Medical Physics, Volume 27, Issue 3, March 2026.
Abstract Purpose To establish the first DRLs for contrast‐enhanced diagnostic pediatric fluoroscopic procedures in Brazil, stratified by body weight, based on data collected in a single tertiary referral public hospital of Rio de Janeiro city. Methods This descriptive, cross‐sectional study included 928 diagnostic fluoroscopy examinations performed in ...
Claudia M. C. Ribeiro   +6 more
wiley   +1 more source

Enfermedad de Hirschsprung en el niño

open access: yesCirugía del Uruguay, 2020
Presentado en sesión de 13 de noviembre de ...
César H Arruti, Ruben Añón
doaj   +2 more sources

Discovery of a Dual‐Target DNAzyme for Clostridioides difficile and Listeria monocytogenes Diagnostics

open access: yesChemistryEurope, Volume 4, Issue 3, March 2026.
A newly discovered fluorogenic DNAzyme, RFD‐CD3, enables rapid and sensitive detection of Clostridioides difficile and—unexpectedly—Listeria monocytogenes, making it the first dual‐responsive DNAzyme for two unrelated bacterial pathogens. Its strong catalytic efficiency, pH‐tolerant activity, and modular trans‐acting design position it as a promising ...
Soyeon Lee   +4 more
wiley   +1 more source

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