Results 51 to 60 of about 11,309 (161)

Successfully Treated Pediatric Patient With Megarectum by Vertical Reduction Rectoplasty [PDF]

Iranian Journal of Colorectal Research, 2014
This report represents successful treatment of a seven-year-old boy with megarectum, who complained of intractable constipation and encopresis, by vertical reduction rectoplasty.
Ibrahim Akkoyun
doaj   +1 more source

Lowering the C‐Reactive Protein (CRP) Threshold Improves Risk Stratification in Acute Ulcerative Colitis: A Propensity‐Matched Analysis

Alimentary Pharmacology &Therapeutics, Volume 64, Issue 7, Page 985-1000, October 2026.
In 503 acute UC admissions, colectomy risk was equivalent between TWC‐positive ASUC and NASUC inpatients after propensity score matching for objective disease severity and treatment exposure; lowering the CRP threshold to ≥ 12 mg/L reclassified 26% of NASUC cases as ASUC and captured 43% of those requiring colectomy within one year, improving ...
Amirah Etchegaray, Naeman Goetz, Katherine Hanigan, Jennifer Phillips, Rina Kumar, George Tambakis, Graham Radford‐Smith, Gareth Walker, Anthony Croft   +8 more
wiley   +1 more source

Chagasic megacolon and large bowel neoplasms: case series and literature review

Journal of Coloproctology, 2011
There is a clear association between chagasic megaesophagus and the esophageal cancer. On the other hand, the association between chagasic megacolon and intestinal neoplasm is uncommon. There are only a few cases described in literature.
Maxwel Capsy Boga Ribeiro, Raquel Franco Leal, Cláudio Saddy Rodrigues Coy, Priscilla de Sene Portel oliveira, Débora Helena Gonçalves Rossi, João José Fagundes, Maria De Lourdes Setsuko Ayrizono   +6 more
doaj   +1 more source

Review Article: Immune Effector Cell‐Mediated Enterocolitis Following CAR‐T Cell Therapy—Clinical Features, Pathophysiology and Management

Alimentary Pharmacology &Therapeutics, Volume 64, Issue 8, Page 1046-1057, October 2026.
Immune effector cell‐mediated enterocolitis is an emerging complication of CAR‐T therapy. This review summarizes its epidemiology, pathophysiology, diagnosis, endoscopic and histopathologic features, and evidence‐based management, emphasizing early recognition, multidisciplinary intervention, and step‐up therapy.
John A. Damianos, Yi Lin, Zongming Eric Chen, Kenneth J. C. Lim, Navreet M. Chowla   +4 more
wiley   +1 more source

Idiopathic megacolon in the BB rat

, 1994
It has been assumed that idiopathic megacolon occurring in the spontaneously diabetic BB rat results from metabolic decompensation associated with diabetes.
Smith, William, Meehan, Christopher J., Baird, Joyce D., Fleming, Stewart   +3 more
core   +2 more sources

Association of chagasic megacolon and cancer of the colon: case report and review of the literature

Revista da Sociedade Brasileira de Medicina Tropical, 2002
There are few descriptions of association between chagasic megacolon and colon cancer. We report a case of obstructive abdomen caused by adenocarcinoma of the left colon in chagasic megacolon.
Sheila Jorge Adad, Renata Margarida Etchebehere, José Ribamar de Araújo, Andrea Berdu Madureira, Vanessa Guimarães Freitas Lima, Alex Augusto da Silva, Crema Eduardo   +6 more
doaj  

Lymphocyte‐C‐Reactive Protein Ratio as Promising New Marker for Predicting Surgical Site Infection in Children With Ulcerative Colitis

Annals of Gastroenterological Surgery, Volume 10, Issue 5, Page 1586-1593, September 2026.
This study identifies the preoperative lymphocyte‐to–C‐reactive protein ratio (LCR) as a potent and independent biomarker for predicting surgical site infection (SSI) in pediatric patients undergoing major surgery for ulcerative colitis. ROC analysis established an optimal cutoff of 5000 (AUC: 0.80), which demonstrated robust predictive performance ...
Yuhki Koike, Koki Higashi, Yuki Sato, Yuka Nagano, Tadanobu Shimura, Takahito Kitajima, Kohei Matsushita, Yoshiki Okita, Yoshinaga Okugawa, Yuji Toiyama   +9 more
wiley   +1 more source

An Adolescent Case of Ulcerative Colitis Complicated by Toxic Megacolon

Case Reports in Gastroenterology
Introduction: Toxic megacolon is a serious complication of ulcerative colitis (UC), characterized by marked colonic dilatation, abnormal bowel function, and systemic toxicity.
Masaki Kato, Masaki Yamashita, Mitsuto Tsukui, Yoshihiko Iijima, Kenichi Araki, Naoki Shikano, Shiori Saji, Kyoko Tsukamoto, Jun Ishida, Takumi Komatsu, Yusuke Nakamoto, Akiyo Kawashima, Akira Endo, Ayako Matsunaga, Yoshinori Sato, Tadateru Maehata, Keisuke Tateishi   +16 more
doaj   +1 more source

Genetic background-dependent abnormalities of the enteric nervous system and intestinal function in Kif26a-deficient mice

Scientific Reports, 2021
The Kif26a protein-coding gene has been identified as a negative regulator of the GDNF-Ret signaling pathway in enteric neurons. The aim of this study was to investigate the influence of genetic background on the phenotype of Kif26a-deficient (KO ...
Yukiko Ohara, Lisa Fujimura, Akemi Sakamoto, Youichi Teratake, Shuichi Hiraoka, Haruhiko Koseki, Takeshi Saito, Keita Terui, Tetsuya Mitsunaga, Mitsuyuki Nakata, Hideo Yoshida, Masahiko Hatano   +11 more
doaj   +1 more source

Multiomics analyses revealed the roles of the epithelial–mesenchymal transition and novel early candidate diagnostic biomarkers in neonatal necrotising enterocolitis

Clinical and Translational Medicine, Volume 16, Issue 9, September 2026.
In infants with necrotising enterocolitis (NEC), excessive inflammation and epithelial cell death promote the epithelial–mesenchymal transition (EMT), leading to damage to intestinal barriers and the translocation of bacteria and toxins. In addition, inflamed epithelia release cytokines to strengthen the inflammatory response.
Xiao‐Chen Liu, Guo‐Bin Liu, Chen Cheng, Jin Zhu, Fei‐Fan Chen, Ying Ji, Yu‐Ni Zhang, Xiao‐Lin Yan, Qing Wang, Xin‐Yu Li, Qing Ai, Yuan Shi, Yu He   +12 more
wiley   +1 more source