Results 51 to 60 of about 8,948 (172)

Epidemiology of Hirschsprung's Disease in Taiwanese Children: A 13-year Nationwide Population-based Study

Pediatrics and Neonatology, 2016
Hirschsprung's disease (HD) is an important colon disease in children. The aim of this study is to describe the epidemiological features of HD in Taiwanese children.
Shu-Ti Chia, Solomon Chih-Cheng Chen, Chin-Li Lu, Shew-Meei Sheu, Hsing-Ching Kuo   +4 more
doaj   +1 more source

Regulation of PHOX2B gene expression by the long non‐coding natural antisense RNA PHOX2B‐AS1

The FEBS Journal, Volume 293, Issue 12, Page 3502-3527, June 2026.
PHOX2B is a transcription factor essential for autonomic nervous system development. We identify and characterize PHOX2B‐AS1, a human long non‐coding antisense transcript at the PHOX2B locus, along with its murine counterpart. Our findings reveal bidirectional transcription and reciprocal regulation: PHOX2B activates PHOX2B‐AS1, whereas PHOX2B‐AS1 ...
Simona Di Lascio, Ana Lucia Cuadros Gamboa, Martina Bertocchi, Filippo Chiesa, Francesca Cargnin, Ettore Mosca, Paride Pelucchi, Viviana Tritto, Stefania Corti, Isabella Ceccherini, Paola Riva, Roberta Benfante, Diego Fornasari   +12 more
wiley   +1 more source

Mother-to-Child Transmission of Congenital Chagas Disease, Japan

Emerging Infectious Diseases, 2014
We report a patient with congenital Chagas disease in Japan. This report reemphasizes the role of neglected and emerging tropical diseases in the era of globalization. It also indicates the need for increased vigilance for detecting Chagas disease in non–
Kazuo Imai, Takuya Maeda, Yusuke Sayama, Kei Mikita, Yuji Fujikura, Kazuhisa Misawa, Morichika Nagumo, Osamu Iwata, Takeshi Ono, Ichiro Kurane, Yasushi Miyahira, Akihiko Kawana, Sachio Miura   +12 more
doaj   +1 more source

Genetic Identification of Potential Drug Targets for Dental Caries: A Mendelian Randomization Study

Health Science Reports, Volume 9, Issue 5, May 2026.
ABSTRACT Background and Aims Dental caries (DC), a chronic and multifactorial disease, affects billions of people globally, posing a significant public health challenge. Despite its prevalence, the molecular mechanisms underlying DC and effective pharmacological targets remain elusive.
Junlei Bi, Anqi Liu, Na Zhang, Yuxin Chen, Changqing Liu, Yongna Zhu, Hebao Wen, Caiyun Ma   +7 more
wiley   +1 more source

Acute colon pseudo-obstruction after percutaneous endoscopic gastrostomy: An unusual co-incidence in a case of acute stroke

Journal of Digestive Endoscopy, 2014
Percutaneous endoscopic gastrostomy (PEG) is a standard procedure for enteral feeding tube placement in the stomach for patients with nonobstructive dysphagia. Major and minor complications have been described in early and delayed phase. We describe a 57-
Suhas D. Wagle, Pradeep G. Divate, Pradeep M. D'Costa, Tushar Kalekar   +3 more
doaj   +1 more source

A Case of Fulminant Immune‐Related Enterocolitis During Immune Checkpoint Inhibitor Therapy for Metastatic Renal Cell Carcinoma

IJU Case Reports, Volume 9, Issue 3, May 2026.
ABSTRACT Introduction Combination therapy with immune checkpoint inhibitors (ICIs) has become a standard treatment for metastatic renal cell carcinoma (mRCC). However, ICIs may also cause immune‐related adverse events. We report a case of mRCC that developed fulminant immune‐related enterocolitis.
Kasumi Kanai, Takayuki Sumiyoshi, Hiroki Kitamoto, Yuki Teramoto, Yuta Mine, Jin Kono, Kimihiko Masui, Takayuki Goto, Ryoichi Saito, Takashi Kobayashi   +9 more
wiley   +1 more source

FROG (Frequency Rates, mOrbidities and timinGs) of Surgical Interventions for UC: A Protocol for an International, Multi‐Centre, Retrospective Cohort Study on Frequency Rates, Morbidities and Timings of Surgical Interventions for Ulcerative Colitis

JCC Plus, Volume 1, Issue 3, May 2026.
ABSTRACT Background The surgical journey of patients diagnosed with ulcerative colitis (UC) typically begins with an index colectomy, which may be followed by restorative procedures or further operations due to complications. Variation in surgical strategies exists, impacting patient outcomes.
Orestis Argyriou, Itai Ghersin, Guy Worley, Phil Tozer, Ailsa Hart, Kapil Sahnan   +5 more
wiley   +1 more source

Systematic Review: The Impact of Geographic Location and Socioeconomic Status on Healthcare Utilisation and Clinical Outcomes in Patients With Inflammatory Bowel Disease (IBD) in the Developed World

JCC Plus, Volume 1, Issue 3, May 2026.
ABSTRACT Background Inflammatory bowel diseases (IBD) are a group of chronic inflammatory conditions affecting the gastrointestinal tract, which requires life‐long management. Healthcare inequalities in IBD are a key factor influencing disease outcomes. Aim This review aimed to describe the impact of geographical location (urban vs.
George Tambakis, Lei Lin, Rina Kumar, Jennifer Phillips, Anthony Croft, Graham Radford‐Smith, Gareth J. Walker   +6 more
wiley   +1 more source

Vólvulo del ciego y dolicomegacolon andino. Reporte de caso

Revista Colombiana de Cirugía
Introducción. Las personas que viven por encima de los 3000 metros sobre el nivel del mar (msnm) tienen los intestinos de mayor longitud y diámetro, característica que ha sido llamada dolicomegacolon andino (DCMA).
Yeni Arroyave-Guerrero
doaj   +1 more source

Pre-Columbian Chagas disease in Brazil: Trypanosoma cruzi I in the archaeological remains of a human in Peruaçu Valley, Minas Gerais, Brazil

Memorias do Instituto Oswaldo Cruz, 2008
We evaluated the presence and distribution of Trypanosoma cruzi DNA in a mummy presenting with megacolon that was dated as approximately 560 ± 40 years old. The mummy was from the Peruaçu Valley in the state of Minas Gerais, Brazil.
Alexandre Fernandes, Alena M Iñiguez, Valdirene S Lima, Sheila MF Mendonça de Souza, Luiz Fernando Ferreira, Ana Carolina P Vicente, Ana M Jansen   +6 more
doaj   +1 more source