Results 71 to 80 of about 22,318 (247)

Efficacy of Filgotinib for Treating Chronic Antibiotic‐Dependent Pouchitis: A Pilot Study

JCC Plus, Volume 1, Issue 2, March 2026.
Chronic pouchitis after restorative proctocolectomy for ulcerative colitis is often difficult to treat. This study evaluated the efficacy of filgotinib for patients with chronic pouchitis. Some patients with chronic pouchitis may be controlled with filgotinib.
Motoi Uchino, Yuki Horio, Ryuichi Kuwahara, Kurando Kusunoki, Kentaro Nagano, Kazunori Nomura, Yusuke Tomoo, Kozo Kataoka, Kei Kimura, Jihyung Song, Ayako Imada, Kazuma Ito, Yuko Fukumoto, Mizuki Koba, Masataka Ikeda, Hiroki Ikeuchi   +15 more
wiley   +1 more source

Clinical efficacy of laparoscopic subtotal colectomy in adult megacolon

Zhongguo linchuang yanjiu, 2023
ObjectiveTo observe the clinical efficacy and safety of laparoscopic subtotal colectomy + loop colostomy in adult patients with megacolon. MethodsRetrospective analysis was performed on the clinical data of 22 adult megacolon patients treated by ...
WANG Qifei, KAN Mingyun, CHENG Hui, SHAO Mingyue, JIANG Zhiwei, GONG Guanwen   +5 more
doaj  

Review of Chagas Disease and Treatment Obstacles to Eradication [PDF]

, 2019
The World Health Organization and the Center for Disease Control reports Chagas disease, or American trypanosomiasis, as a major neglected tropical disease prevalent in 21 endemic Latin American countries.
Sherman, Emily
core   +1 more source

Clinical course of severe colitis: a comparison between Crohn’s Disease and ulcerative colitis [PDF]

, 2013
Pochi sono i dati disponibili sul decorso clinico della malattia di Crohn del colon severa(CD). L'obiettivo è quello di descrivere il decorso clinico della colite di Crohn severa (CC) in una coorte di pazienti isolata con CD del colon o ileocolica, e di ...
Modesto, Irene <1978>
core   +1 more source

Preterm Birth International Collaborative Australasia Branch: Expert Consensus on Diagnosis and Treatment of Neonatal Lactose Intolerance (2025)

Pediatric Discovery, Volume 4, Issue 1, March 2026.
ABSTRACT This consensus aims to standardize the diagnosis and management of neonatal lactose intolerance (LI). A multidisciplinary working group was established under the auspices of the Preterm Birth International Collaborative (Australasia Branch). The development process included a comprehensive literature review of databases, which identified 61 ...
Zhengli Wang, Shuping Han, Xinzhu Lin, Hui Wu, Lingfen Xu, Jun Tang, Wei Hao, Chao Yu, Xiaomei Tong, Juan Zhang, Rong Ju, Xiaoli Xie, Long Chen, Fang Li, Xingwang Zhu, Liping Xu, Lanlan Geng, Wei Zhou, Xueyun Ren, Chuanfeng Li, Guoping Chen, Wenyan Tang, Jiang Duan, Zhi Zhao, Tao Pan, Zhongliang Li, Yingli Wu, Siqi Zhuang, Ying Ouyang, Falin Xu, Zheng Chen, Yiyang Liu, Zhoujie Peng, Lei Bao, Yu He, Lin Kong, Xianlan Zheng, Lijuan Xu, Qiao Shen, Qian Zhang, Junli Li, Junjun Wang, Yuan Shi   +42 more
wiley   +1 more source

Chagasic megacolon and large bowel neoplasms: case series and literature review

Journal of Coloproctology, 2011
There is a clear association between chagasic megaesophagus and the esophageal cancer. On the other hand, the association between chagasic megacolon and intestinal neoplasm is uncommon. There are only a few cases described in literature.
Maxwel Capsy Boga Ribeiro, Raquel Franco Leal, Cláudio Saddy Rodrigues Coy, Priscilla de Sene Portel oliveira, Débora Helena Gonçalves Rossi, João José Fagundes, Maria De Lourdes Setsuko Ayrizono   +6 more
doaj   +1 more source

Genetic background-dependent abnormalities of the enteric nervous system and intestinal function in Kif26a-deficient mice

Scientific Reports, 2021
The Kif26a protein-coding gene has been identified as a negative regulator of the GDNF-Ret signaling pathway in enteric neurons. The aim of this study was to investigate the influence of genetic background on the phenotype of Kif26a-deficient (KO ...
Yukiko Ohara, Lisa Fujimura, Akemi Sakamoto, Youichi Teratake, Shuichi Hiraoka, Haruhiko Koseki, Takeshi Saito, Keita Terui, Tetsuya Mitsunaga, Mitsuyuki Nakata, Hideo Yoshida, Masahiko Hatano   +11 more
doaj   +1 more source

Foxf1 and Foxf2 control murine gut development by limiting mesenchymal Wnt signaling and promoting extracellular matrix production [PDF]

, 2006
Development of the vertebrate gut is controlled by paracrine crosstalk between the endodermal epithelium and the associated splanchnic mesoderm. In the adult, the same types of signals control epithelial proliferation and survival, which account for the ...
Astorga (Johansson), Jeanette, Carlsson, Peter, Johansson, Bengt R, Landgren, Henrik, Miura, Naoyuki, Ormestad, Mattias, Wang, Tao   +6 more
core   +2 more sources

Male-Biased Aganglionic Megacolon in the TashT Mouse Line Due to Perturbation of Silencer Elements in a Large Gene Desert of Chromosome 10

PLoS Genetics, 2015
Neural crest cells (NCC) are a transient migratory cell population that generates diverse cell types such as neurons and glia of the enteric nervous system (ENS).
K. Bergeron, Tatiana Cardinal, A. M. Touré, M. Béland, D. Raiwet, D. Silversides, N. Pilon   +6 more
semanticscholar   +1 more source

A randomised phase I study of etrolizumab (rhuMAb β7) in moderate to severe ulcerative colitis. [PDF]

, 2013
ObjectiveEtrolizumab (rhuMAb β7, anti-β7, PRO145223) is a humanised monoclonal antibody targeting the β7 subunit of the heterodimeric integrins α4β7 and αEβ7, which are implicated in leucocyte migration and retention in ulcerative colitis (UC).
Baumgart, Daniel C, Bressler, Brian, Danilenko, Dimitri, Egen, Jackson, Fedorak, Richard N, Hommes, Daan W, Keir, Mary, Luca, Diana, Mansfield, John C, O'Byrne, Sharon, Rutgeerts, Paul J, Schreiber, Stefan, Sturm, Andreas, Tang, Meina, Visich, Jennifer, Wei, Xiaohui, Williams, Marna   +16 more
core