The LAV‐BPIFB4‐Platelet‐CD47 Axis: A Novel Mechanism Associated With Immune Resilience in Longevity
Centenarians display elevated CD47+ reticulated platelets, a trait recapitulated in LAV‐BPIFB4 carriers on total platelet pool. LAV‐BPIFB4 drives an early acquirement of CD47 surface expression, enabling platelets to suppress monocyte IL‐6 release. rhLAV‐BPIFB4 phenocopies the effects in non‐genetic carriers, establishing the platelet–CD47–monocyte ...
Elena Ciaglia +13 more
wiley +1 more source
Synergistic effects of luspatercept and cyclosporine A in lower-risk myelodysplastic syndrome with red cell aplasia: Two case insights. [PDF]
Jo T +6 more
europepmc +1 more source
ABSTRACT Objective This systematic review and meta‐analysis aimed to evaluate the risk of thromboembolic events and assess the overall safety and effectiveness of avatrombopag in adult patients with immune thrombocytopenia using real‐world evidence. Methods A systematic search was conducted following the PRISMA 2020 guidelines.
M. L. Lozano, D. Valcarcel
wiley +1 more source
Give megs a break: minor DNA stress, platelets in excess. [PDF]
Kimmerlin Q, Strassel C.
europepmc +1 more source
Beyond Hemostasis: Platelet Biomarkers and Vascular‐Immune Crosstalk in Dengue
Several biomarkers are associated with platelet activation during dengue virus (DENV) infection. These include serum markers (AST, ALT, ferritin), platelet surface or secreted molecules (P‐selectin, PF4, RANTES, VEGF‐A, CD40L, TREM‐1, TLT‐1), immune and endothelial markers (TREM‐1, Ang‐1, Ang‐2), and viral components such as DENV EIII.
Amanda Beatriz Adriano da Silva‐Alencar +6 more
wiley +1 more source
Platelet dysfunction in chronic kidney disease arises from bone marrow remodeling and megakaryocyte reprogramming. [PDF]
Carminita E +17 more
europepmc +1 more source
ON THE ALLEGED PHAGOCYTOSIS BY MEGAKARYOCYTES [PDF]
openaire +2 more sources
This Is Not a Myeloproliferative Neoplasm…
Pediatric Blood &Cancer, Volume 73, Issue 7, July 2026.
Stephanie Juané Kennedy
wiley +1 more source
Immature platelet fraction and bone marrow findings in hematology. [PDF]
Yamasaki S +6 more
europepmc +1 more source
Molecular and Functional Platelet Abnormalities in Myeloproliferative Neoplasms. [PDF]
Wang AX, Guo BB, Linden MD.
europepmc +1 more source

