Results 151 to 160 of about 21,749 (244)

The Role of EVs in the Aging Hematopoietic System

Aging Cell, Volume 25, Issue 10, October 2026.
Extracellular vesicles from aged bone marrow carry pro‐inflammatory cargo that drives blood stem cell decline, while youthful vesicles restore or maintain stem cell function. Circulating vesicles therefore represent both a readout of hematopoietic aging and a potential therapeutic route.
Esra G. Kosebent, Nathalie Havranek, Karoline Kollmann, Kristina Kirschner, Eszter Doma, Kavya Gupta   +5 more
wiley   +1 more source

Megakaryocytes Internalize and Are Activated by Immune Complexes. [PDF]

Circ Res
Puhm F, Allaeys I, Petito E, Sang Y, Tupin F, Dos Santos Pereira Andrade A, Doré E, Dubuc I, Vaillancourt M, Dieudé M, Hébert MJ, Florea BI, Trépanier P, Washington VA, Senis Y, Fortin PR, Brisson AR, Wolberg AS, Bury L, Flamand L, Boilard E.   +20 more
europepmc   +1 more source

Neonatal-Onset Refractory Thrombocytopenia and Anemia Associated With a Homozygous In-Frame NFE2 Duplication. [PDF]

Am J Case Rep
Uddin MS, Albehair M, Alshammari FNM, Esmail A, Shafeen K, Bin Hassan A, Bawazier H.   +6 more
europepmc   +1 more source

From haemostasis to immunity: The expanding frontiers of platelet biology

British Journal of Haematology, Volume 209, Issue 4, Page 1482-1485, October 2026.
Platelets are versatile cells whose functions extend far beyond haemostasis and thrombosis, actively regulating innate and adaptive immunity, angiogenesis, lymphangiogenesis, liver regeneration, atherosclerosis and tumour metastasis. This demonstrates their central role in various physiological processes and multiple life‐threatening diseases ...
Xun Grace Wu, Nicole Tomei, Heyu Ni
wiley   +1 more source

Are Myeloproliferative Neoplasms-Unclassifiable Really Unclassifiable? [PDF]

EJHaem
Barosi G, Rosti V, Gale RP.
europepmc   +1 more source

Effect of efgartigimod IV on immature platelet fraction in primary immune thrombocytopenia in the ADVANCE IV trial

British Journal of Haematology, Volume 209, Issue 4, Page 1932-1936, October 2026.
Elevated percentage of immature platelets is indicative of consumptive thrombocytopenic disorders. In immune thrombocytopenia, low platelet counts may result from reduced production or increased degradation, both driven by IgG autoantibodies. By blocking FcRn, efgartigimod decreases immature platelet fraction, likely by reducing platelet degradation ...
Hanny Al‐Samkari, Filip Matthijssens, Kaichi Nishiwaki, Francesco Zaja, Sylvian Audia, Yoshitaka Miyakawa, Jaume Ayguasanosa, Damien Chimits, Anna Hultberg, Peter Ulrichts   +9 more
wiley   +1 more source

HAT regimen attenuates NF-κb-driven megakaryocyte apoptosis and neuronal cell death in sepsis: convergent mechanisms protecting thrombocytopenia and cognitive function. [PDF]

Front Cell Dev Biol
Hui Z, Shen N, Zhang H, Yu M, Li Z, Ping J, Fu Q.   +6 more
europepmc   +1 more source

The lung is more than an organ of gas exchange: immunocompetency, platelets and implications for drug discovery

British Journal of Pharmacology, Volume 183, Issue 20, Page 5999-6006, October 2026.
Abstract The lungs have for a long time been recognised as having pharmacological significance as a specific organ to modulate the pharmacokinetics of endogenous substances needed to maintain homeostasis. The lungs are therefore the site of action of certain drugs that act on these homeostatic processes, resulting in systemic effects on the ...
Simon C. Pitchford
wiley   +1 more source

Case Report: Persistent severe thrombocytopenia after adjuvant ado-trastuzumab emtansine with sequential bone marrow findings and romiplostim support. [PDF]

Front Oncol
Qiao D, Nie L, Liu S, Ding HB.
europepmc   +1 more source

Updates and controversies in contemporary grading of clear cell renal cell carcinoma and papillary renal cell carcinoma

Histopathology, Volume 89, Issue 4, Page 574-589, October 2026.
New concepts, innovations and some issues have emerged since the adoption a decade ago of WHO/ISUP grading for CCRCC and PRCC. Continued use of the WHO/ISUP grading for CCRCC and PRCC has been upheld by newer studies, and practice guidance for some of the grading issues, where data are available, is provided.
Gladell P. Paner, Mahul. B. Amin, Jung Woo Kwon, Liang Cheng, Holger Moch   +4 more
wiley   +1 more source