Results 131 to 140 of about 21,749 (244)

Aberrant Myelopoiesis and Haematopoietic Stem Cell Niche Remodelling Precedes Cancer Cachexia Onset in a Sex‐Dependent Manner

Journal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 5, October 2026.
ABSTRACT Background Male cancer patients are 30% more likely to develop cachexia compared to females; however, the underlying aetiology remains unknown. Myelopoiesis induces inflammation in cancer cachexia, which contributes to muscle atrophy. Whether differences in myelopoiesis during cancer cachexia initiation contribute to sex‐based differences in ...
Alice Tate, Alex Brown, Lisa Ek Orloff, James Vanhie, Nicolas Collao, Cooper Brabrook, Victoria Moghadam, Vedrana Rajaković, Nadine Wiper‐Bergeron, Michael De Lisio   +9 more
wiley   +1 more source

Menin-dependent megakaryocyte proliferation and fibrosis in myeloproliferative neoplasms. [PDF]

Cancer Cell
Wen J, Cotton A, Mehmood R, Mohan M, Hall T, Broadhurst AL, Zhang K, Olufadi Y, Kang G, Marcellino B, Mascarenhas J, Hoffman R, Janke LJ, Gurbuxani S, McGeehan GM, Crispino JD.   +15 more
europepmc   +1 more source

Reversible Eltrombopag‐Associated Bone Marrow Fibrosis With Hematologic Recovery After Drug Withdrawal in ASXL1‐Mutated Hypoplastic Myelodysplastic Syndrome: A Case Report

eJHaem, Volume 7, Issue 5, October 2026.
ABSTRACT Hypoplastic myelodysplastic syndrome (MDS) often overlaps clinically with aplastic anemia and frequently involves clonal hematopoiesis. Thrombopoietin receptor agonists (TPO‐RAs), including eltrombopag, are increasingly used to treat cytopenias in hypoplastic marrow failure syndromes; however, their long‐term effects on clonal dynamics and ...
Kyoko Yoshihara, Ikuo Matsuda, Yasuhito Nannya, Mami Samori, Naru Tomigaki, Saki Takahashi, Chisato Ohe, Satoshi Yoshihara   +7 more
wiley   +1 more source

Association of hemoglobin level with granulocyte engraftment and red blood cell transfusion by transplant type after hematopoietic stem cell transplantation: a retrospective cohort study. [PDF]

Ann Med
Wang J, Wang J, Ying Q, Lv D, Zhang P.
europepmc   +1 more source

Megakaryocytes in Peripheral Blood Smears

Turkish Journal of Hematology, 2019
Neha Garg, Rashmi Jain Gupta, Sunil Kumar   +2 more
doaj   +1 more source

Hematologic Malignancies With RUNX1::ZFPM2 Translocation: A Case Report and Literature Review

eJHaem, Volume 7, Issue 5, October 2026.
ABSTRACT RUNX1 rearrangements are recurrent in myeloid neoplasms, but rare fusion partners remain poorly characterized. We report the first acute myeloid leukemia (AML) with a RUNX1::ZFPM2 fusion generated by t(8;21)(q23;q22). A 72‐year‐old woman presented with acute myelomonocytic leukemia carrying concomitant IDH2 and NRAS mutations.
Marie Temple, Romain Vazquez, Estelle Balducci, Lucile Couronné, Rudy Birsen, Anne‐Laure Roupie, Justine Decroocq, Cyrielle Rodier, Lise Willems, Nicolas Chapuis, Carole Almire, Ismaël Boussaid, Michaela Fontenay, Didier Bouscary, Olivier Kosmider, Chloé Friedrich   +15 more
wiley   +1 more source

Temporal Lysophosphatidic Acid Supplementation Enhances Megakaryocyte Differentiation and Platelet Production From Human Hematopoietic Progenitors. [PDF]

Cell Biol Int
Jiamvoraphong N, Lorthongpanich C, Septham P, Klaihmon P, Kheolamai P, Laowtammathron C, Imsoonthornruksa S, Ketudat-Cairns M, Issaragrisil S.   +8 more
europepmc   +1 more source

Pediatric Essential Thrombocythemia With a Novel CALR Mutation: A Case Report

eJHaem, Volume 7, Issue 5, October 2026.
ABSTRACT Pediatric essential thrombocythemia (ET) is extremely rare and frequently lacks identifiable driver mutations. We report a case of a 5‐year‐old male with ET harboring a novel CALR exon 9 frameshift mutation complicated by acquired von Willebrand syndrome.
Kana Tsuji, Suguru Uemura, Tomoko Fujikawa, Nobuyuki Yamamoto, Aiko Kozaki, Atsuro Saito, Toshiaki Ishida, Takeshi Mori, Makiko Yoshida, Takahiro Okutani, Daiichiro Hasegawa   +10 more
wiley   +1 more source

The thrombopoietin receptor S264F mutant drives MPN with marrow fibrosis through a dual mechanism

HemaSphere, Volume 10, Issue 10, October 2026.
Charlotte Lees, Emile Brandt, Emmanuel Dutranoix, Gabriel Levy, Bogdan I. Iorga, Hosuk Ryou, Jens Rittscher, Daniel Royston, Stefan N. Constantinescu, Adam J. Mead   +9 more
wiley   +1 more source

When Liver Disease Misleads the Diagnosis: Two Cases of TAFRO Syndrome With Porto‐Sinusoidal Vascular Disease

eJHaem, Volume 7, Issue 5, October 2026.
ABSTRACT Background TAFRO syndrome is a rare inflammatory disorder whose hepatic manifestations may mimic decompensated cirrhosis. Cases: We report two women with TAFRO syndrome associated with portal‐sinusoidal vascular disorder (PSVD), a rare cause of non‐cirrhotic portal hypertension. In both cases, liver biopsy excluded cirrhosis and confirmed PSVD.
Laura Dassy, Fanny Poletti, Kaoutar Hafraoui, Marie Lejeune, Joan Somja, Patrick Collins, Julien Guiot, Ivan Theate, Jo Caers, Jean Delwaide, Astrid Marot, Virginie Putzeys, Gaëlle Vertenoeil   +12 more
wiley   +1 more source