Results 91 to 100 of about 7,888 (191)

Understanding Megakaryopoiesis and Thrombopoiesis Using Human Stem Cells Models [PDF]

, 2017
Human stem cell models (CD34+ hematopoietic progenitors, embryonic stem cells and induced pluripotent stem cells (iPSCs)) are powerful tools for the study of megakaryopoiesis and thrombopoiesis, particularly in situations where mouse models are ...
Sim, Xiu Li
core  

Regulation of T-cell adhesion and megakaryopoiesis by immune adaptor ADAP [PDF]

The immune adaptor ADAP possesses versatile roles in a variety of immune cells, including T cells, dendritic cells, macrophages, and platelets, etc. The most extensivelystudied role of ADAP is that it couples TCR activation to integrin activation and T ...
Xiong, Y
core   +1 more source

FLI1 Expression Levels during Megakaryopoiesis Affect Thrombopoiesis and Platelet Biology [PDF]

, 2017
Friend Leukemia Virus Integration 1 (FLI1) is a critical transcription factor (TF) in terminal megakaryocyte differentiation. It is amongst the genes missing from an inherited hemizygous deletion on chromosome 11q termed Jacobsen syndrome and often ...
Vo, Karen, Vo, Karen K
core  

Dachshund Homolog 1: Unveiling Its Potential Role in Megakaryopoiesis and Bacillus anthracis Lethal Toxin-Induced Thrombocytopenia

Lethal toxin (LT) is the critical virulence factor of Bacillus anthracis, the causative agent of anthrax. One common symptom observed in patients with anthrax is thrombocytopenia, which has also been observed in mice injected with LT.
Chi-Yuan Liao, Yu-Shan Liou, Guan-Ling Lin, Yi-Ling Lai, Tso-Fu Wang, Hui-Ling Hsu, Wei-Ting Lin, Jyh-Hwa Kau, Hsin-Hsien Huang, Sung-Chao Chu, Der-Shan Sun, Min-Hua Hsieh, Chi-Chih Tsai, Hsin-Hou Chang, Po-Kong Chen   +14 more
core   +1 more source

Megakaryopoiesis in chronic myeloproliferative diseases. A morphometric evaluation with special emphasis on primary thrombocythemia.

, 1984
Morphometry was employed on different entities of chronic myeloproliferative diseases (CMPD) and reactive lesions in addition to normal control specimens. The entities studied included: (1) inflammatory reactions of the bone marrow (so-called myelitis in
Funke, S, Georgii, A, Holgado, S, Thiele, J, Choritz, H   +4 more
core  

The Role of DIAPH1 in the Megakaryopoiesis

Le rôle de DIAPH1 dans la mégacaryopoïèse Les mégacaryocytes sont les précurseurs cellulaires hautement spécialisés qui produisent des plaquettes via des extensions cytoplasmiques appelées proplaquettes. La formation des proplaquettes exige de profonds changements dans l’organisation du cytosquelette: microtubules et actine.
openaire   +2 more sources

Megakaryocytes in myelofibrosis: mechanisms of fibrotic niche remodeling and therapeutic implications. [PDF]

Biomark Res
Huang J, Yin X, Shi X, Yang X, Li R, Zhang X, Zhang Y, Tong H, Jin J, Huang J.   +9 more
europepmc   +1 more source

Chemotherapy-induced thrombocytopenia: from "platelet counting" to ecological repair of the bone marrow. [PDF]

Support Care Cancer
Liu T, Xie R, He Q, Ma J.
europepmc   +1 more source

CCL5 exposure promotes acute and transient megakaryopoiesis and hematopoietic progenitor expansion. [PDF]

Stem Cell Reports
Barrachina MN, Lee DH, Camacho V, Wang KG, Walsey E, Carminita E, Becker IC, Branfield S, Freire D, Nikols E, Berdan EL, Yohannes B, Miladinovic O, Tilburg J, Italiano JE, Machlus KR.   +15 more
europepmc   +1 more source

Scalable bioreactor manufacturing of iPSC-derived megakaryocytes with Proanthocyanidin A supplementation: a strategic platform for military blood supply resilience. [PDF]

Mil Med Res
Dettmer R, Rovai A, Wolkers W, Blasczyk R, Figueiredo C.   +4 more
europepmc   +1 more source