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The changing pattern of megaloblastic anemia: megaloblastic anemia in Israel
American Journal of Clinical Nutrition, 1983The causes of megaloblastic anemia were studied in a survey of patients admitted to six Israeli hospitals over a period of 15 yr. Among the 203 patients identified, 69% had pernicious anemia, 12% had gastrointestinal disease, 9% had primary nutritional deficiency of whom only 1% were associated with pregnancy, and 7% had selective vitamin B12 ...
C Hershko
exaly +3 more sources
Thiamine-responsive megaloblastic anemia syndrome
International Journal of Hematology, 2010 Thiamine-responsive megaloblastic anemia (TRMA) syndrome usually associated with diabetes mellitus, anemia and deafness, due to mutations in SLC19A2, encoding a thiamine transporter protein. The onset of disease is usually seen during infancy or at early
Fatma Gumruk +2 more
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Hyperpigmentation in megaloblastic anemia
Journal of the American Academy of Dermatology, 1985Generalized hyperpigmentation developed over 2 years in a 65-year-old woman. A diagnosis of pernicious anemia was made, and treatment with vitamin B12 led to complete reversion of her hyperpigmentation to normal. Literature pertinent to hyperpigmentation and its association with megaloblastic anemias is reviewed and several possible mechanisms are ...
V J, Marks, R A, Briggaman, C E, Wheeler
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Treatment of megaloblastic anemias
Journal of Chronic Diseases, 1957Abstract Megaloblastic anemia is almost always the consequence of a deficiency state. The proper management of this disorder requires the identification of the nature of the underlying abnormality, since this dictates the choice of the specific therapeutic agent for the deficiency, the duration of treatment required, and the other therapeutic ...
P A, McINTYRE, J R, KREVANS, C L, CONLEY
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Postgraduate Medicine, 1978
Most, but not all, megaloblastic anemia is produced by "ineffective erythropoiesis" in the bone marrow due to either folic acid or vitamin B12 deficiency. In folic acid deficiency the cause frequently is inadequate dietary intake, whereas vitamin B12 deficiency is almost always conditioned by some specific type of malabsorption.
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Most, but not all, megaloblastic anemia is produced by "ineffective erythropoiesis" in the bone marrow due to either folic acid or vitamin B12 deficiency. In folic acid deficiency the cause frequently is inadequate dietary intake, whereas vitamin B12 deficiency is almost always conditioned by some specific type of malabsorption.
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Hyperpigmentation in Megaloblastic Anemia
International Journal of Dermatology, 1988ABSTRACT: Hyperpigmentation of the hands and feet developed in a 65–year–old Korean woman who had undergone a total gastrectomy and esophagojejunostomy due to early gastric cancer 7 years previously. A diagnosis of megaloblastic anemia due to vitamin B12deficiency was made.
S H, Lee +4 more
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Diagnosis Of Megaloblastic Anemia
Annual Review of Medicine, 1991Megaloblastic anemia can be due to cobalamin deficiency, folate deficiency, or refractory forms of bone marrow disease. This essay reviews current thinking on the diagnostic procedures available to a physician considering these disorders. The questions to be answered are as follows: Is a megaloblastic anemia present?
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