Results 121 to 130 of about 857 (142)

Construction and analysis of experimental DNA vaccines against megalocytivirus

Fish & Shellfish Immunology, 2012
Iridoviruses are large double-stranded DNA viruses with icosahedral capsid. The Iridoviridae family contains five genera, one of which is Megalocytivirus. Megalocytivirus has emerged in recent years as an important pathogen to a wide range of marine and freshwater fish.
Min, Zhang, Yong-Hua, Hu, Zhi-Zhong, Xiao, Yun, Sun, Li, Sun   +4 more
openaire   +2 more sources

Molecular detection and phylogenetic analysis of megalocytivirus in Brazilian ornamental fish

Archives of Virology, 2018
Megalocytiviruses have a worldwide distribution, causing serious economic loss to the global aquaculture industry. They also present a threat to ornamental fish trade because megalocytiviral infections have unspecified symptoms, making early diagnosis difficult.
Samara Rita, de Lucca Maganha, Pedro Henrique Magalhães, Cardoso, Simone, de Carvalho Balian, Sabrina Ribeiro, de Almeida-Queiroz, Andrezza Maria, Fernandes, Ricardo Luiz Moro, de Sousa   +5 more
openaire   +2 more sources

Megalocytivirus-induced proteins of turbot (Scophthalmus maximus): Identification and antiviral potential

Journal of Proteomics, 2013
Megalocytivirus is an important fish pathogen with a broad host range that includes turbot. In this study, proteomic analysis was conducted to examine turbot proteins modulated in expression by megalocytivirus infection. Thirty five proteins from spleen were identified to be differentially expressed at 2days post-viral infection (dpi) and 7dpi.
Jian, Zhang, Yong-hua, Hu, Zhi-zhong, Xiao, Li, Sun   +3 more
openaire   +2 more sources

Neomycin inhibits Megalocytivirus infection in fish by antagonizing the increase of intracellular reduced glutathione

Fish & Shellfish Immunology, 2022
Infectious spleen and kidney necrosis virus (ISKNV) is the type species of the Megalocytivirus genus that infects a number of marine and freshwater fishes, causing huge economic losses in aquaculture. The ISKNV infection leads to increase of reducing power in cells.
Hengwei Deng, Yeyu Li, Jinling Li, Wenjie Shen, Qiankang Chen, Shaoping Weng, Jianguo He, Xiaopeng Xu   +7 more
openaire   +2 more sources

The megalocytivirus-induced protein CsMig1 enhances Cynoglossus semilaevis resistance against viral infection

Veterinary Immunology and Immunopathology, 2013
Half-smooth tongue sole (Cynoglossus semilaevis) is an important economic fish species cultured in northern China. In this study, we identified and analyzed the expression and function of a megalocytivirus-induced gene, CsMig1, from tongue sole. The deduced amino acid sequence of CsMig1 is composed of 507 residues and contains no conserved domains ...
Wei, Wang, Zhi-zhong, Xiao, Li, Sun
openaire   +2 more sources

Genetic diversity of Megalocytivirus from cultured fish in Korea

Aquaculture, 2019
Abstract Since the first outbreak of Megalocytivirus infection in cultured marine fish in the 1990s, the Red sea bream iridovirus (RSIV) subtype II and Turbot reddish body iridovirus (TRBIV) type Megalocytivirus have been prevalent in Korea. Based on the major capsid protein (MCP) genes, the RSIV subtype II, as the predominant genotype, was ...
Kwang Il Kim, Eun Sun Lee, Jeong Wan Do, Seong Don Hwang, Miyoung Cho, Sung Hee Jung, Bo Young Jee, Woo Ju Kwon, Hyun Do Jeong   +8 more
openaire   +1 more source

Isolation and characterisation of an ISKNV-genotype megalocytivirus from imported angelfish Pterophyllum scalare

Diseases of Aquatic Organisms, 2020
Using cultures of the SKF-9 cell line, megalocytivirus AFIV-16 was isolated from imported angelfish Pterophyllum scalare held in quarantine at the Australian border. The cytopathic effect caused by isolate AFIV-16 presented as cell rounding and enlargement, but complete destruction of the infected cell cultures did not occur.
Yasuhiko, Kawato, Peter G, Mohr, Mark St J, Crane, Lynette M, Williams, Matthew J, Neave, David M, Cummins, Megan, Dearnley, Sandra, Crameri, Clare, Holmes, John, Hoad, Nicholas J G, Moody   +10 more
openaire   +2 more sources

ORF75 of megalocytivirus RBIV-C1: A global transcription regulator and an effective vaccine candidate

Fish & Shellfish Immunology, 2015
Megalocytivirus, a DNA virus belonging to the Iridoviridae family, is a severe pathogen to a wide range of marine and freshwater fish. In this study, using turbot (Scophthalmus maximus) as a host model, we examined the immunoprotective property of one megalocytivirus gene, ORF75, in the form of DNA vaccine (named pORF75).
Jian, Zhang, Mo-Fei, Li
openaire   +2 more sources

First report of megalocytivirus (iridoviridae) in cultured bluegill sunfish, Lepomis macrochirus, in China

Microbial Pathogenesis, 2019
The bluegill sunfish, Lepomis macrochirus, is an important aquacultural and recreational species in southern China because of its excellent taste, rapid growth rate, and good looks. At present, few pathogens are known to affect the bluegill sunfish. However, an iridovirus-like disease recently caused heavy losses to the bluegill sunfish aquaculture ...
Lihui, Liu, Lujun, Yu, Xiaozhe, Fu, Qiang, Lin, Hongru, Liang, Yinjie, Niu, Ningqiu, Li   +6 more
openaire   +2 more sources

First report of megalocytivirus in ornamental fish in Italy

2023
Introduction: The trade in marine ornamental fish is a multi-billion-dollar industry involving over 50 exporting and importing countries. Europe is one of the three major importers of marine ornamental fish, along with the United States and Japan. Megalocytiviruses are associated with severe mortality in ornamental fish aquaculture, including both ...
Ciulli S., Volpe E., Errani F., Pritelli A., Magi G. E   +4 more
openaire   +2 more sources