Interplay between Lipid Metabolism, Lipid Droplets, and DNA Virus Infections [PDF]
Cells, 2022 Lipid droplets (LDs) are cellular organelles rich in neutral lipids such as triglycerides and cholesterol esters that are coated by a phospholipid monolayer and associated proteins. LDs are known to play important roles in the storage and availability of
Mónica A. Farías +4 more
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Human papilloma and other DNA virus infections of the cervix: A population based comparative study among tribal and general population in India. [PDF]
PLoS ONE, 2019 BackgroundDespite being preventable, cervical cancer remains a major health concern among women. Persistent Human Papillomavirus (HPV) and other viral co-infections may influence cervical dysplasia.
Supriti Ghosh +9 more
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Bacterial Infections, DNA Virus Infections, and RNA Virus Infections Manifest Differently in Neutrophil Receptor Expression [PDF]
The Scientific World Journal, 2012 Treating viral illnesses or noninfective causes of inflammation with antibiotics is ineffective and contributes to the development of antibiotic resistance, toxicity, and allergic reactions, leading to increasing medical costs.
Esa-Matti Lilius, Jari Nuutila
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TRIM29 promotes DNA virus infections by inhibiting innate immune response [PDF]
Nature Communications, 2017 Proteins of the TRIM family have regulatory functions in immune signaling, often via ubiquitination of target proteins. Here, the authors show that TRIM29 is induced upon infection with DNA viruses, resulting in degradation of STING, decreased interferon
Junji Xing +6 more
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Activation and Evasion of RLR Signaling by DNA Virus Infection [PDF]
Frontiers in Microbiology, 2021 Antiviral innate immune response triggered by nucleic acid recognition plays an extremely important role in controlling viral infections. The initiation of antiviral immune response against RNA viruses through ligand recognition of retinoic acid ...
Junli Jia +4 more
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Hepatitis B Virus DNA Integration, Chronic Infections and Hepatocellular Carcinoma
Microorganisms, 2021 Hepatitis B Virus (HBV) is an Old World virus with a high mutation rate, which puts its origins in Africa alongside the origins of Homo sapiens, and is a member of the Hepadnaviridae family that is characterized by a unique viral replication cycle.
Maria Bousali +3 more
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Quantitative conversion of biomass in giant DNA virus infection [PDF]
Scientific Reports, 2021 AbstractBioconversion of organic materials is the foundation of many applications in chemical engineering, microbiology and biochemistry. Herein, we introduce a new methodology to quantitatively determine conversion of biomass in viral infections while simultaneously imaging morphological changes of the host cell.
Kördel, Mikael +8 more
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Kidney Transplant-Associated Viral Infection Rates and Outcomes in a Single-Centre Cohort
Viruses, 2022 Background: Opportunistic infections remain a significant cause of morbidity and mortality after kidney transplantation. This retrospective cohort study aimed to assess the incidence and predictors of post-transplant DNA virus infections (CMV, EBV, BKV ...
Kairi Pullerits +7 more
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From infection to cancer: how DNA tumour viruses alter host cell central carbon and lipid metabolism [PDF]
Open Biology, 2021 Infections cause 13% of all cancers globally, and DNA tumour viruses account for almost 60% of these cancers. All viruses are obligate intracellular parasites and hijack host cell functions to replicate and complete their life cycles to produce progeny ...
Kamini L. Magon, Joanna L. Parish
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Nuclear Soluble cGAS Senses DNA Virus Infection [PDF]
SSRN Electronic Journal, 2021 ABSTRACT The cytosolic DNA sensor cGAS detects foreign DNA from pathogens or self-DNA from cellular damage and instigates type I interferon (IFN) expression. Recent studies find that cGAS also localizes in the nucleus and binds the chromatin.
Yakun Wu +4 more
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