Giant viruses of amoebas: an update [PDF]
Frontiers in Microbiology, 2016 During the 12 past years, five new or putative virus families encompassing several members, namely Mimiviridae, Marseilleviridae, pandoraviruses, faustoviruses, and virophages were described.
Sarah eAherfi +7 more
doaj +3 more sources
Amoebae, Giant Viruses, and Virophages Make Up a Complex, Multilayered Threesome [PDF]
Frontiers in Cellular and Infection Microbiology, 2018 Viral infection had not been observed for amoebae, until the Acanthamoeba polyphaga mimivirus (APMV) was discovered in 2003. APMV belongs to the nucleocytoplasmatic large DNA virus (NCLDV) family and infects not only A.
Jan Diesend +3 more
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A new Zamilon-like virophage partial genome assembled from a bioreactor metagenome [PDF]
Frontiers in Microbiology, 2015 Virophages replicate within viral factories inside the Acanthamoeba cytoplasm, and decrease the infectivity and replication of their associated giant viruses.
Meriem eBekliz +8 more
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MimiLook: A Phylogenetic Workflow for Detection of Gene Acquisition in Major Orthologous Groups of Megavirales. [PDF]
Viruses, 2017 With the inclusion of new members, understanding about evolutionary mechanisms and processes by which members of the proposed order, Megavirales, have evolved has become a key area of interest.
Jain S +4 more
europepmc +6 more sources
Sequence analysis of malacoherpesvirus proteins: Pan-herpesvirus capsid module and replication enzymes with an ancient connection to "Megavirales". [PDF]
Virology, 2018 The order Herpesvirales includes animal viruses with large double-strand DNA genomes replicating in the nucleus. The main capsid protein in the best-studied family Herpesviridae contains a domain with HK97-like fold related to bacteriophage head proteins, and several virion maturation factors are also homologous between phages and herpesviruses.
Mushegian A, Karin EL, Pupko T.
europepmc +4 more sources
DNA repair genes in the Megavirales pangenome. [PDF]
Current Opinion in Microbiology, 2016 The order 'Megavirales' represents a group of eukaryotic viruses with a large genome encoding a few hundred up to two thousand five hundred genes. Several members of Megavirales possess genes involved in major DNA repair pathways. Some of these genes were likely inherited from an ancient virus world and some others were derived from the genomes of ...
Romain Blanc-Mathieu, H. Ogata
semanticscholar +3 more sources
Mimiviridae, Marseilleviridae, and virophages as emerging human pathogens causing healthcare-associated infections [PDF]
GMS Hygiene and Infection Control, 2014 [english] Aim: During the last decade it became obvious that viruses belonging to and families (order Megavirales), may be potential causative agents of pneumonia. Thus, we have performed a review of the association of , , and virophages with pneumonia,
Kutikhin, Anton G. +2 more
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Reclassification of Giant Viruses Composing a Fourth Domain of Life in the New Order Megavirales [PDF]
Intervirology, 2012 Interest in giant viruses has risen sharply since 2003, following the discovery of the Mimivirus and four other protist-infecting giant viruses that are linked to the nucleocytoplasmic large DNA viruses (NCLDVs).
P. Colson +3 more
semanticscholar +4 more sources
"Megavirales", a proposed new order for eukaryotic nucleocytoplasmic large DNA viruses. [PDF]
Arch Virol, 2013 The nucleocytoplasmic large DNA viruses (NCLDVs) comprise a monophyletic group of viruses that infect animals and diverse unicellular eukaryotes. The NCLDV group includes the families Poxviridae, Asfarviridae, Iridoviridae, Ascoviridae, Phycodnaviridae, Mimiviridae and the proposed family "Marseilleviridae".
Colson P +11 more
europepmc +7 more sources
The analysis of translation-related gene set boosts debates around origin and evolution of mimiviruses. [PDF]
PLoS Genetics, 2017 The giant mimiviruses challenged the well-established concept of viruses, blurring the roots of the tree of life, mainly due to their genetic content.
Jônatas Santos Abrahão +3 more
doaj +2 more sources