Results 11 to 20 of about 585 (133)

Giant viruses of amoebas: an update [PDF]

Frontiers in Microbiology, 2016
During the 12 past years, five new or putative virus families encompassing several members, namely Mimiviridae, Marseilleviridae, pandoraviruses, faustoviruses, and virophages were described.
Sarah eAherfi, Sarah eAherfi, Philippe eColson, Philippe eColson, Bernard eLa Scola, Bernard eLa Scola, Didier eRaoult, Didier eRaoult   +7 more
doaj   +3 more sources

Amoebae, Giant Viruses, and Virophages Make Up a Complex, Multilayered Threesome [PDF]

Frontiers in Cellular and Infection Microbiology, 2018
Viral infection had not been observed for amoebae, until the Acanthamoeba polyphaga mimivirus (APMV) was discovered in 2003. APMV belongs to the nucleocytoplasmatic large DNA virus (NCLDV) family and infects not only A.
Jan Diesend, Janis Kruse, Monica Hagedorn, Christian Hammann   +3 more
doaj   +3 more sources

A new Zamilon-like virophage partial genome assembled from a bioreactor metagenome [PDF]

Frontiers in Microbiology, 2015
Virophages replicate within viral factories inside the Acanthamoeba cytoplasm, and decrease the infectivity and replication of their associated giant viruses.
Meriem eBekliz, Jonathan eVerneau, Samia eBenamar, Didier eRaoult, Didier eRaoult, Bernard eLa Scola, Bernard eLa Scola, Philippe eColson, Philippe eColson   +8 more
doaj   +3 more sources

MimiLook: A Phylogenetic Workflow for Detection of Gene Acquisition in Major Orthologous Groups of Megavirales. [PDF]

Viruses, 2017
With the inclusion of new members, understanding about evolutionary mechanisms and processes by which members of the proposed order, Megavirales, have evolved has become a key area of interest. The central role of gene acquisition has been shown in previous studies. However, the major drawback in gene acquisition studies is the focus on few MV families
Jain S, Panda A, Colson P, Raoult D, Pontarotti P.   +4 more
europepmc   +6 more sources

Sequence analysis of malacoherpesvirus proteins: Pan-herpesvirus capsid module and replication enzymes with an ancient connection to "Megavirales". [PDF]

Virology, 2018
The order Herpesvirales includes animal viruses with large double-strand DNA genomes replicating in the nucleus. The main capsid protein in the best-studied family Herpesviridae contains a domain with HK97-like fold related to bacteriophage head proteins, and several virion maturation factors are also homologous between phages and herpesviruses.
Mushegian A, Karin EL, Pupko T.
europepmc   +4 more sources

DNA repair genes in the Megavirales pangenome [PDF]

Current Opinion in Microbiology, 2016
The order 'Megavirales' represents a group of eukaryotic viruses with a large genome encoding a few hundred up to two thousand five hundred genes. Several members of Megavirales possess genes involved in major DNA repair pathways. Some of these genes were likely inherited from an ancient virus world and some others were derived from the genomes of ...
Romain Blanc-Mathieu, Hiroyuki Ogata
openaire   +3 more sources

"Megavirales", a proposed new order for eukaryotic nucleocytoplasmic large DNA viruses. [PDF]

Arch Virol, 2013
The nucleocytoplasmic large DNA viruses (NCLDVs) comprise a monophyletic group of viruses that infect animals and diverse unicellular eukaryotes. The NCLDV group includes the families Poxviridae, Asfarviridae, Iridoviridae, Ascoviridae, Phycodnaviridae, Mimiviridae and the proposed family "Marseilleviridae".
Colson P, De Lamballerie X, Yutin N, Asgari S, Bigot Y, Bideshi DK, Cheng XW, Federici BA, Van Etten JL, Koonin EV, La Scola B, Raoult D.   +11 more
europepmc   +7 more sources

Reclassification of Giant Viruses Composing a Fourth Domain of Life in the New Order <b><i>Megavirales</i></b> [PDF]

Intervirology, 2012
Interest in giant viruses has risen sharply since 2003, following the discovery of the Mimivirus and four other protist-infecting giant viruses that are linked to the nucleocytoplasmic large DNA viruses (NCLDVs). Despite considerable heterogeneity in hosts and genome sizes, the NCLDVs have been shown to be monophyletic based on analyses of their ...
Philippe Colson, Xavier de Lamballerie, Ghislain Fournous, Didier Raoult   +3 more
openaire   +2 more sources

Cytochromes b5 Occurrence in Viruses Belonging to the Order Megavirales

Research Square
Abstract Cytochrome b5 is a small electron transport protein that is found in animals, plants, fungi and photosynthetic proteobacteria where it plays key metabolic roles in energy production, lipid and sterol biosynthesis and cytochrome P450 biochemistry.
Lamb, David C., Goldstone, Jared V., Belhaouari, Djamal Brahim, Andréani, Julien, Farooqi, Ayesha, Allen, Michael J., Kelly, Steven L., La Scola, Bernard, Stegeman, John J.   +8 more
openaire   +3 more sources

The analysis of translation-related gene set boosts debates around origin and evolution of mimiviruses. [PDF]

PLoS Genetics, 2017
The giant mimiviruses challenged the well-established concept of viruses, blurring the roots of the tree of life, mainly due to their genetic content.
Jônatas Santos Abrahão, Rodrigo Araújo, Philippe Colson, Bernard La Scola   +3 more
doaj   +2 more sources