MimiLook: A Phylogenetic Workflow for Detection of Gene Acquisition in Major Orthologous Groups of Megavirales [PDF]
With the inclusion of new members, understanding about evolutionary mechanisms and processes by which members of the proposed order, Megavirales, have evolved has become a key area of interest. The central role of gene acquisition has been shown in previous studies. However, the major drawback in gene acquisition studies is the focus on few MV families
Philippe Colson +2 more
exaly +6 more sources
Sequence analysis of malacoherpesvirus proteins: Pan-herpesvirus capsid module and replication enzymes with an ancient connection to “Megavirales” [PDF]
The order Herpesvirales includes animal viruses with large double-strand DNA genomes replicating in the nucleus. The main capsid protein in the best-studied family Herpesviridae contains a domain with HK97-like fold related to bacteriophage head proteins, and several virion maturation factors are also homologous between phages and herpesviruses.
Arcady R Mushegian, Tal Pupko
exaly +4 more sources
“Megavirales”, a proposed new order for eukaryotic nucleocytoplasmic large DNA viruses [PDF]
The nucleocytoplasmic large DNA viruses (NCLDVs) comprise a monophyletic group of viruses that infect animals and diverse unicellular eukaryotes. The NCLDV group includes the families Poxviridae, Asfarviridae, Iridoviridae, Ascoviridae, Phycodnaviridae, Mimiviridae and the proposed family "Marseilleviridae".
Philippe Colson +2 more
exaly +7 more sources
Welcome to pandoraviruses at the 'Fourth TRUC’ club [PDF]
Nucleocytoplasmic large DNA viruses (NCLDVs), or representatives of the proposed order Megavirales, belong to families of giant viruses that infect a broad range of eukaryotic hosts.
Vikas eSharma +8 more
doaj +2 more sources
Kaumoebavirus, a New Virus That Clusters with Faustoviruses and Asfarviridae [PDF]
In this study, we report the isolation of a new giant virus found in sewage water from the southern area of Jeddah (Saudi Arabia), with morphological and genomic resemblance to Faustoviruses.
Leena H. Bajrai +6 more
doaj +2 more sources
On the occurrence of cytochrome P450 in viruses. [PDF]
Author Posting. © The Author(s), 2019. This is the author's version of the work. It is posted here by permission of National Academy of Sciences for personal use, not for redistribution. The definitive version was published in Proceedings of the National
Lamb DC +9 more
europepmc +4 more sources
Amoebae, Giant Viruses, and Virophages Make Up a Complex, Multilayered Threesome [PDF]
Viral infection had not been observed for amoebae, until the Acanthamoeba polyphaga mimivirus (APMV) was discovered in 2003. APMV belongs to the nucleocytoplasmatic large DNA virus (NCLDV) family and infects not only A.
Jan Diesend +3 more
doaj +2 more sources
A Large Open Pangenome and a Small Core Genome for Giant Pandoraviruses [PDF]
Giant viruses of amoebae are distinct from classical viruses by the giant size of their virions and genomes. Pandoraviruses are the record holders in size of genomes and number of predicted genes. Three strains, P. salinus, P. dulcis, and P.
Sarah Aherfi +11 more
doaj +2 more sources
The Double-Stranded DNA Virosphere as a Modular Hierarchical Network of Gene Sharing [PDF]
Virus genomes are prone to extensive gene loss, gain, and exchange and share no universal genes. Therefore, in a broad-scale study of virus evolution, gene and genome network analyses can complement traditional phylogenetics.
Jaime Iranzo +2 more
doaj +2 more sources
Mimiviridae, Marseilleviridae, and virophages as emerging human pathogens causing healthcare-associated infections [PDF]
[english] Aim: During the last decade it became obvious that viruses belonging to and families (order Megavirales), may be potential causative agents of pneumonia. Thus, we have performed a review of the association of , , and virophages with pneumonia,
Kutikhin, Anton G. +2 more
doaj +2 more sources

