A Family of Novel Cyclophilins, Conserved in the Mimivirus Genus of the Giant DNA Viruses [PDF]
Computational and Structural Biotechnology Journal, 2018 The cyclophilin (abbreviated here as CYN) family represents a large group of protein prolyl isomerase (PPIase), many of which are also chaperones that promote proper folding of a large variety of client proteins. Over the past few years, megaviruses with
Sailen Barik
doaj +3 more sources
Welcome to pandoraviruses at the 'Fourth TRUC’ club [PDF]
Frontiers in Microbiology, 2015 Nucleocytoplasmic large DNA viruses (NCLDVs), or representatives of the proposed order Megavirales, belong to families of giant viruses that infect a broad range of eukaryotic hosts.
Vikas eSharma +8 more
doaj +4 more sources
Kaumoebavirus, a New Virus That Clusters with Faustoviruses and Asfarviridae [PDF]
Viruses, 2016 In this study, we report the isolation of a new giant virus found in sewage water from the southern area of Jeddah (Saudi Arabia), with morphological and genomic resemblance to Faustoviruses.
Leena H. Bajrai +6 more
doaj +3 more sources
Viral metagenomic analysis of fecal samples reveals an enteric virome signature in irritable bowel syndrome [PDF]
BMC Microbiology, 2020 Background Changes in the enteric microbiota have been suggested to contribute to gastrointestinal diseases, including irritable bowel syndrome. Most of the published work is on bacterial dysbiosis with meager data on the role of the virome in irritable ...
Mina Hojat Ansari +6 more
doaj +3 more sources
Amoebae, Giant Viruses, and Virophages Make Up a Complex, Multilayered Threesome [PDF]
Frontiers in Cellular and Infection Microbiology, 2018 Viral infection had not been observed for amoebae, until the Acanthamoeba polyphaga mimivirus (APMV) was discovered in 2003. APMV belongs to the nucleocytoplasmatic large DNA virus (NCLDV) family and infects not only A.
Jan Diesend +3 more
doaj +3 more sources
Mimiviridae, Marseilleviridae, and virophages as emerging human pathogens causing healthcare-associated infections [PDF]
GMS Hygiene and Infection Control, 2014 [english] Aim: During the last decade it became obvious that viruses belonging to and families (order Megavirales), may be potential causative agents of pneumonia. Thus, we have performed a review of the association of , , and virophages with pneumonia,
Kutikhin, Anton G. +2 more
doaj +3 more sources
Ancestrality and Mosaicism of Giant Viruses Supporting the Definition of the Fourth TRUC of Microbes [PDF]
Frontiers in Microbiology, 2018 Giant viruses of amoebae were discovered in 2003. Since then, their diversity has greatly expanded. They were suggested to form a fourth branch of life, collectively named ‘TRUC’ (for “Things Resisting Uncompleted Classifications”) alongside Bacteria ...
Philippe Colson +10 more
doaj +2 more sources
The analysis of translation-related gene set boosts debates around origin and evolution of mimiviruses. [PDF]
PLoS Genetics, 2017 The giant mimiviruses challenged the well-established concept of viruses, blurring the roots of the tree of life, mainly due to their genetic content.
Jônatas Santos Abrahão +3 more
doaj +2 more sources
Origin of giant viruses from smaller DNA viruses not from a fourth domain of cellular life. [PDF]
Virology, 2014 The numerous and diverse eukaryotic viruses with large double-stranded DNA genomes that at least partially reproduce in the cytoplasm of infected cells apparently evolved from a single virus ancestor.
Yutin N, Wolf YI, Koonin EV.
europepmc +2 more sources
Virus Genomes from Deep Sea Sediments Expand the Ocean Megavirome and Support Independent Origins of Viral Gigantism [PDF]
mBio, 2019 The nucleocytoplasmic large DNA viruses (NCLDV) of eukaryotes (proposed order, “Megavirales”) include the families Poxviridae, Asfarviridae, Iridoviridae, Ascoviridae, Phycodnaviridae, Marseilleviridae, and Mimiviridae, as well as still unclassified ...
Disa Bäckström +9 more
doaj +2 more sources