Results 61 to 70 of about 12,780 (229)

Substrate for Thyroid Hormone Synthesis: Biochemistry, Evolution, and Physiology

The FASEB Journal, Volume 40, Issue 8, 30 April 2026.
Two proposed sequence of events for thyroxine formation in patients expressing mutant thyroglobulin. (A) (1) TSH stimulation drives expression of misfolded TG. (2) Unremitting ER stress. (3) Stress‐induced cell death. (4) Dead thyrocytes release their contents. (5) The contents become iodinated. (6) Forming thyroxine.
Crystal Young, Peter Arvan
wiley   +1 more source

Preliminary investigation on the establishment of a new meibomian gland obstruction model and gene expression

Scientific Reports
Meibomian gland dysfunction is a chronic ocular surface disease with a complex pathogenesis, whose main clinical manifestations are meibomian gland obstruction or/and lipid abnormalities. To explore the mechanism of MGD due to meibomian gland obstruction
Ming Sun, Huanmin Cheng, Zheng Yang, Jiangqin Tang, Shengshu Sun, Zhanglin Liu, Shaozhen Zhao, Lijie Dong, Yue Huang   +8 more
doaj   +1 more source

Correlation Study Between Abnormal Morphology of Meibomian Glands and Meibum in Patients With Dry Eye Disease Under in vivo Confocal Microscopy

Frontiers in Medicine, 2022
Objective: To observe differences in meibomian gland morphology among patients with meibomian gland dysfunction (MGD) with liquid meibum, with solid meibum, and a non-MGD group by laser scanning in vivo confocal microscopy (IVCM), and then analyze the ...
Qian Zheng, Yuanyuan Xue, Xiaowei Zhong, Guangwei Li, Weiyun Shi, Weiyun Shi, Weiyun Shi, Ting Wang, Ting Wang, Ting Wang   +9 more
doaj   +1 more source

Awareness of treatment: a source of bias in subjective grading of ocular complications [PDF]

, 2019
Purpose: Bias has been described as one important obstacle in scientific research. The aim of this study was to explore “awareness of treatment” as a possible source of bias in subjective grading of ocular complications.
Cardona Torradeflot, Genís, Esterich, Noelia   +1 more
core   +2 more sources

The 2D:4D Digit Ratio and Primary Sjögren's Syndrome: A Window Into Prenatal Hormonal Influences on Exocrine Autoimmunity

American Journal of Human Biology, Volume 38, Issue 4, April 2026.
ABSTRACT Objectives The pronounced female preponderance in Sjögren's syndrome (SS) points to a potential role for sex hormones in disease development. The ratio of the second to fourth digit (2D:4D), which serves as an indirect marker of fetal androgen exposure, has shown associations with several immune‐mediated conditions.
Mustafa Gür, Ramazan Fazil Akkoc, Burak Oz, Ahmet Karatas, Süleyman Serdar Koca   +4 more
wiley   +1 more source

Repeatability of Meibomian Gland Contrast, a Potential Indicator of Meibomian Gland Function. [PDF]

, 2019
PurposeMeibomian gland contrast may be a potential indicator of gland health, especially among isotretinoin users. We aimed to develop a repeatable and reliable method for measuring Meibomian gland contrast from meibography images.MethodsLower lid (LL ...
Lin, Meng C, Yeh, Thao N
core  

Relevance of Lipid-Based Products in the Management of Dry Eye Disease [PDF]

, 2017
Components of the ocular surface synergistically contribute to maintaining and protecting a smooth refractive layer to facilitate the optimal transmission of light.
Amrane, Mourad, Faure, Marie-Odile, Garrigue, Jean-Sebastien, Holopainen, Juha M., Tong, Louis   +4 more
core   +1 more source

Brain Involvement in Leishmaniasis

Cell Biochemistry and Function, Volume 44, Issue 4, April 2026.
ABSTRACT Leishmaniasis is a neglected tropical disease caused by infection with the protozoan parasite Leishmania and it is a significant global health problem. The disease has a wide clinical spectrum, from tegumentary leishmaniasis (TL) that encompasses cutaneous (CL), mucosal (ML) and cutaneous‐diffuse (CDL) forms, to the potentially fatal systemic ...
Camila S. Freitas, Eduardo A. F. Coelho, Myron Christodoulides   +2 more
wiley   +1 more source

Visible Meibomian Gland Structure Increases After Vectored Thermal Pulsation Treatment in Dry Eye Disease Patients with Meibomian Gland Dysfunction

Clinical Ophthalmology, 2020
Arjan S Hura,1 Alice T Epitropoulos,2 Craig N Czyz,3,4 Eric D Rosenberg5 1Department of Ophthalmology University of Cincinnati, Cincinnati, OH, USA; 2Ophthalmic Surgeons & Consultants of Ohio Inc., Columbus, OH, USA; 3Ophthalmology, Section ...
Hura AS, Epitropoulos AT, Czyz CN, Rosenberg ED   +3 more
doaj  

Physical Therapy Modalities of Western Medicine and Traditional Chinese Medicine for Meibomian Gland Dysfunction

Digital Chinese Medicine, 2020
The meibomian gland is a unique sebaceous gland located in the eyelid. Its main function is to secrete lipids and form the lipid layer of the tear film to delay the evaporation of waterborne tears, increase the surface tension of the tear film, and to ...
Li Jie, Ou Shang-Kun, Li Wei, Liu Zu-Guo, Peng Qing-Hua   +4 more
doaj   +1 more source