Results 61 to 70 of about 173,374 (209)
DAMPs, PAMPs, and Alarmins: From Mechanism to Therapy
This review synthesizes the expanding biology of PAMPs and DAMPs, from their molecular sources and sensing mechanisms to regulatory networks that govern inflammation and homeostasis. Spanning from classical immune activation to trained immunity and interorgan communication, we highlight the interplay between PAMPs and DAMPs and their context‐dependent ...
Xuanxuan Yu +6 more
wiley +1 more source
Meibomian Gland Morphology Among Patients Presenting for Refractive Surgery Evaluation
Cassandra C Brooks, Preeya K Gupta Department of Ophthalmology, Duke University Eye Center, Durham, NC, USACorrespondence: Preeya K GuptaDuke University Eye Center at Page Road, 4709 Creekstone Drive, Suite 100, Durham, NC 27703, USAEmail preeya.gupta ...
Brooks CC, Gupta PK
doaj
Demodex Infestation in Patients With Atopic Dermatitis Treated With Dupilumab: A Case–Control Study
ABSTRACT Atopic dermatitis (AD) is a chronic inflammatory skin disease in which dupilumab, an interleukin‐4 receptor alpha antagonist, has become a cornerstone therapy for moderate‐to‐severe disease. However, persistent facial and neck erythema and related symptoms have been increasingly reported during dupilumab treatment, and the underlying ...
Pinar Dursun +2 more
wiley +1 more source
Abstract Purpose Immune checkpoint inhibitors (ICIs) have transformed cancer therapy but may cause immune‐related adverse events (irAEs), including dry eye disease (DED). This study aimed to quantify the incidence of ICI‐associated DED and to evaluate factors contributing to variability across studies.
Kai‐Yang Chen +2 more
wiley +1 more source
ABSTRACT This retrospective analysis evaluated 12 dogs with hepatocellular carcinoma (HCC) who received stereotactic body radiation therapy (SBRT). Dogs received between 6 and 25 Grey (Gy) per fraction for 1–5 fractions for a total dose of 13–30 Gy. Eleven patients (92%) experienced acute adverse effects (AE), with the majority being VRTOG grade 2–3 ...
Victoria Lee Newberry +3 more
wiley +1 more source
Arjan S Hura,1 Alice T Epitropoulos,2 Craig N Czyz,3,4 Eric D Rosenberg5 1Department of Ophthalmology University of Cincinnati, Cincinnati, OH, USA; 2Ophthalmic Surgeons & Consultants of Ohio Inc., Columbus, OH, USA; 3Ophthalmology, Section ...
Hura AS +3 more
doaj
ABSTRACT Objective To assess the clinical effects of a compounded 0.03% tacrolimus in 0.75% cross‐linked hyaluronic acid (XHA) on tear quantity, quality, and ocular surface health in dogs with evaporative dry eye disease (EDED). Procedures Sixteen client‐owned dogs diagnosed with EDED (normal aqueous production yet reduced stability) were enrolled in ...
Lionel Sebbag +4 more
wiley +1 more source
EFFICACY OF CYCLOSPORINE EYE DROPS IN TREATMENT OF MEIBOMIAN GLAND DISEASE
Objective: To assess the efficacy of topical cyclosporine ophthalmic solution in patients with Meibomian Gland Disease. Study Design: Quasi-experimental study.
Fatima Khan +5 more
doaj +4 more sources
SOAT1 Nonsense Variant in a Cat With Sebaceous Gland Dysplasia
ABSTRACT We investigated a random‐bred cat with sebaceous gland dysplasia. The cat presented with hypotrichosis and dark crusts on the skin. Histopathologically, sebaceous glands were enlarged and had an abnormal morphology with an increased number of undifferentiated reserve cells.
Lia Kammermann +5 more
wiley +1 more source
Temporal variations in meibomian gland structure—A pilot study [PDF]
Purpose: To investigate whether there is a measurable change in meibomian gland morphological characteristics over the course of a day (12h) and over a month.Methods: The study enrolled 15 participants who attended a total of 11 study visits spanning a 5-
Maldonado‐codina, Carole; id_orcid +5 more
core +1 more source

