Repeatability of Meibomian Gland Contrast, a Potential Indicator of Meibomian Gland Function [PDF]
Cornea, 2018 Purpose: Meibomian gland contrast may be a potential indicator of gland health, especially among isotretinoin users. We aimed to develop a repeatable and reliable method for measuring Meibomian gland contrast from meibography images.
Yeh, Thao N, Lin, Meng C
openaire +4 more sources
Characteristics of tear film lipid layer in young dry eye patients
Journal of the Formosan Medical Association, 2021 Background/Purpose: To investigate the characteristics of subjective symptoms and objective parameters among young patients with dry eye disease (DED) and compare them with those of older patients.
Hsin-Yu Weng +4 more
doaj +1 more source
Relevance of Lipid-Based Products in the Management of Dry Eye Disease [PDF]
, 2017 Components of the ocular surface synergistically contribute to maintaining and protecting a smooth refractive layer to facilitate the optimal transmission of light.
Amrane, Mourad +4 more
core +1 more source
Congenital aniridia: European COST action ANIRIDIA‐NET guidelines for diagnosis, management and care
Acta Ophthalmologica, EarlyView.Abstract Congenital aniridia is a rare ocular disorder affecting the majority of eye structures and can be associated with systemic manifestations. The main visible phenotypic characteristic is the partial or complete absence of the iris; however, foveal hypoplasia is a more frequent and reliable clinical sign. Other ocular comorbidities are associated
Davide Romano +26 more
wiley +1 more source
Could Ocular Glands Be Infected by SARS-CoV-2?
DiseasesThe aim of the study was to investigate the expression levels of ACE2 in ocular glands and to investigate the effect of S protein on them. Male C57BL/6J mice were used for the experiments. The expression levels of ACE2 are highest in the Meibomian glands,
Jinghua Bu +5 more
doaj +1 more source
Apocrine glands in the eyelid of primates contribute to the ocular host defense [PDF]
, 2004 Apocrine glands of Moll are regular components of primate eyelids. We studied the distribution and localization of these glands in three different primate species, the common marmoset, the rhesus monkey, and the hamadryas baboon.
Stoeckelhuber, B. M. +2 more
core +1 more source
Outcome parameters in studies investigating dry eye disease: A systematic literature review
Acta Ophthalmologica, EarlyView.Abstract The development of effective therapeutics for dry eye disease (DED) is challenging due to its complex pathophysiology, heterogeneous patient presentation and the significant failure rate of previous clinical development programs. This underlines the importance of the selection of appropriate endpoints for clinical trials.
Viktoria Pai +8 more
wiley +1 more source
Renewal of the Holocrine Meibomian Glands by Label-Retaining, Unipotent Epithelial Progenitors
Stem Cell Reports, 2016 The meibomian and sebaceous glands secrete lipids to prevent desiccation of the ocular surface and skin, respectively. Precisely how these holocrine tissues regenerate is not well understood.
Geraint J. Parfitt +6 more
doaj +1 more source
Tacrolimus and Hyaluronate Therapy Enhance Tear Film Stability in Canine Evaporative Dry Eye Disease
Veterinary Ophthalmology, EarlyView.ABSTRACT Objective Evaluate the efficacy of a therapeutic approach combining tacrolimus and hyaluronate‐based lubricant for the management of evaporative dry eye disease (EDED) in dogs, compared to hyaluronate monotherapy. Procedures Fifty‐four client‐owned dogs with EDED were randomly assigned to three groups (n = 18 each): Group 1 received 0.03 ...
Lionel Sebbag +2 more
wiley +1 more source
Assessment of meibomian glands using a custom–made meibographer in dry eye patients in Ghana
BMC Ophthalmology, 2018 Background Meibomian Gland Dysfunction (MGD) is a leading cause of evaporative Dry Eye Disease (DED). This makes non-invasive meibography an important procedure in the clinical evaluation of DED patients.
Eugene Appenteng Osae +4 more
doaj +1 more source