Results 41 to 50 of about 5,436 (176)

Effects of Isotretinoin on Meibomian Glands [PDF]

open access: yesOptometry and Vision Science, 2015
ABSTRACT The authors have reviewed the potential etiology and long‐standing consequences of isotretinoin use in the development of dry eye symptoms in the absence of significant clinical findings. Despite the normal appearance of meibomian gland structure on meibography and minimal signs of eyelid margin inflammation, the secretory ...
Moy, Allison   +2 more
openaire   +4 more sources

Retrospective Analysis of Survival and Adverse Effects Associated With Stereotactic Body Radiation Therapy in 12 Dogs With Hepatocellular Carcinoma

open access: yesVeterinary and Comparative Oncology, EarlyView.
ABSTRACT This retrospective analysis evaluated 12 dogs with hepatocellular carcinoma (HCC) who received stereotactic body radiation therapy (SBRT). Dogs received between 6 and 25 Grey (Gy) per fraction for 1–5 fractions for a total dose of 13–30 Gy. Eleven patients (92%) experienced acute adverse effects (AE), with the majority being VRTOG grade 2–3 ...
Victoria Lee Newberry   +3 more
wiley   +1 more source

Dry Eye and Meibomian Gland Dysfunction in Neovascular Age-Related Macular Degeneration Patients Treated with Intravitreal Injections

open access: yesTürk Oftalmoloji Dergisi, 2022
Objectives:To determine if patients treated with multiple intravitreal injections for neovascular age-related macular degeneration are more likely to suffer from dry eye and meibomian gland dysfunction.Materials and Methods:Sixty eyes of 30 patients were
Pelin Kıyat   +3 more
doaj   +1 more source

Repeatability of keratometry depending on tear film osmolarity

open access: yesActa Ophthalmologica, Volume 104, Issue 5, Page e530-e537, August 2026.
Abstract Purpose To determine the repeatability of keratometry and astigmatism measurements of patients depending on the tear film osmolarity using three different devices. Methods In this study, 97 eyes of 97 patients with a mean age of 64.92 ± 12.07 years received three repeated measurements with the IOLMaster 700 (Carl Zeiss Meditec, Jena, Germany),
David Schneider   +4 more
wiley   +1 more source

Effects of radiation therapy on the meibomian glands and dry eye in patients with ocular adnexal mucosa-associated lymphoid tissue lymphoma

open access: yesBMC Ophthalmology, 2020
Background Radiation therapy (RT) is the treatment of choice in patients with low-grade ocular adenexal mucosa-associated lymphoid tissue lymphoma (OAML) and many of them experience post-RT dry eye with varying severity.
Sung Eun Kim   +2 more
doaj   +1 more source

Dysfunction of the meibomian glands in patients with diabetes mellitus

open access: yesСахарный диабет, 2022
The prevalence of diabetes mellitus has increased in recent decades. The most common ophthalmic manifestations of diabetes mellitus are retinopathy, epitheliopathies, corneal erosion and dry eye syndrome, the symptoms of which are more pronounced than in
T. N. Safonova, E. S. Medvedeva
doaj   +1 more source

Randomized comparison of lipid‐containing and non‐lipid‐containing artificial tears on tear film dynamics over a 3‐month period

open access: yesOptometry and Vision Science, Volume 103, Issue 7, July 2026.
ABSTRACT Purpose To study the effects of a lipid‐containing artificial tear (AT) and a non‐lipid‐containing AT on tear film dynamics over a 3‐month period. Methods Subjects with low lipid layer thickness were randomized to lipid‐containing or non‐lipid‐containing ATs for 3 months.
Jennifer E. Ding   +11 more
wiley   +1 more source

Molecular Basis and Clinical Spectrum of WNT10A‐Related Oligodontia

open access: yesClinical Genetics, Volume 110, Issue 1, Page 3-14, July 2026.
Cellular Mechanism behind WNT10A phenotypes. ABSTRACT WNT10A mutations, a major genetic determinant of dental agenesis and ectodermal dysplasia, exert profound effects on craniofacial development. Although classified as rare disorders, these mutations account for more than half of oligodontia cases, reflecting their critical role.
Perennes Elise   +5 more
wiley   +1 more source

Deep Phenotyping and Molecular Elucidation of a New Syndrome: Ectodermal Dysplasia Caused by IRF6 Variants

open access: yesExperimental Dermatology, Volume 35, Issue 7, July 2026.
ABSTRACT The diagnosis of an ectodermal dysplasia (ED) is often made by dermatologists. Some of the more than 50 distinct ectodermal dysplasias, however, are still largely unknown and their pathogenesis is poorly understood. Since we recently discovered that variants of the Interferon Regulatory Factor 6 (IRF6) gene IRF6 may cause ED, we have further ...
Holm Schneider   +7 more
wiley   +1 more source

Evolving treatments for Sjögren disease: current approaches and emerging targets

open access: yesInternal Medicine Journal, Volume 56, Issue 7, Page 1126-1133, July 2026.
Abstract Sjögren disease (SjD) is a prevalent systemic autoimmune condition characterised by exocrine gland dysfunction, systemic inflammation and heterogeneous organ involvement. Current management remains largely symptomatic, with no approved disease‐modifying therapies available and substantial unmet clinical need. However, advances in understanding
Mansi Bhurani   +3 more
wiley   +1 more source

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