Results 71 to 80 of about 11,383 (251)

Discovery of a novel thiophene carboxamide analogue as a highly potent and selective sphingomyelin synthase 2 inhibitor for dry eye disease therapy

open access: yesActa Pharmaceutica Sinica B
Dry eye disease (DED) is a prevalent and intractable ocular disease induced by a variety of causes. Elevated sphingomyelin (SM) levels and pro-inflammatory cytokines were detected on the ocular surface of DED patients, particularly in the meibomian ...
Jintong Yang   +16 more
doaj   +1 more source

A clinical utility assessment of the automatic measurement method of the quality of Meibomian glands

open access: yesBioMedical Engineering OnLine, 2017
Background Meibomian gland dysfunction (MGD) is one of the most common diseases observed in clinics and is the leading cause of evaporative dry eye. Today, diagnostics of MGD is not fully automatic yet and is based on a qualitative assessment made by an ...
Robert Koprowski   +2 more
doaj   +1 more source

Regenerative Therapies in Dry Eye Disease: From Growth Factors to Cell Therapy [PDF]

open access: yes, 2017
Dry eye syndrome is a complex and insidious pathology with a high level of prevalence among the human population and with a consequently high impact on quality of life and economic cost.
Alcoholado, Cristina   +7 more
core   +3 more sources

Meibomian gland dysfunction. III. Meibomian gland lipids.

open access: yesInvestigative ophthalmology & visual science, 1989
The lipid components of meibomian gland excreta were evaluated in rabbits after they received 2% topical epinephrine dropped into their eyes daily for a period of 6 months to a year to induce meibomian gland dysfunction (MGD). Changes were compared to excreta obtained from seven age-matched, untreated control rabbits.
N, Nicolaides   +3 more
openaire   +1 more source

Mainstream Artificial Intelligence Technologies in Contemporary Ophthalmology

open access: yesAdvanced Intelligent Systems, Volume 7, Issue 12, December 2025.
This review explores the latest artificial intelligence (AI) technologies in ophthalmology, focusing on four key data types: medical imaging, electronic health records, robotic‐assisted surgery, and genomics. It examines the structural features, use cases, clinical goals, and evaluation metrics of various AI algorithms, while also introducing emerging ...
Shiqi Yin   +9 more
wiley   +1 more source

Rosácea ocular: revisão [PDF]

open access: yes, 2012
Rosacea is a prevalent chronic cutaneous disorder with variable presentation and severity. Although considered a skin disease, rosacea may evolve the eyes in 58-72% of the patients, causing eyelid and ocular surface inflammation.
Hofling-Lima, Ana Luisa   +2 more
core   +2 more sources

Integration of Cholesterol Oxidase‐Based Biosensors on a Smart Contact Lens for Wireless Cholesterol Monitoring from Tears

open access: yesAdvanced Intelligent Systems, Volume 7, Issue 12, December 2025.
The combination of a parity‐time symmetry wireless technology with a cholesterol sensor integrated into a smart contact lens enables high‐sensitivity cholesterol sensing at low concentration. Cholesterol plays a critical role in physiological functions, but elevated levels increase the risk of cardiovascular disease.
Yang Cui   +4 more
wiley   +1 more source

Identification of meibomian gland testosterone metabolites produced by tissue-intrinsic intracrine deactivation activity

open access: yesiScience
Summary: Intracrinology—wherein hormones are synthesized in the organ where they exert their effect without release into circulation—has been described.
Khanh Tien Nguyen Pham   +9 more
doaj   +1 more source

Método de Stades para a correção da triquíase-entrópio da pálpebra superior : resultados e acompanhamento de 21 casos [PDF]

open access: yes, 2000
Triquíase é a condição na qual os cílios e os cabelos faciais crescem em direção à córnea ou conjuntiva. Os pêlos que surgem de locais normais estão apontados em uma direção anormal. Essa condição pode ser causada por dobras nasais proeminentes, entrópio,
Bolzan, Aline Adriana   +4 more
core   +1 more source

An Update on Bioactive Lipids: Fatty Acid Esters of Hydroxy Fatty Acids in Food

open access: yesFood Chemistry International, Volume 1, Issue 4, Page 366-374, December 2025.
This review focused on the dietary sources, bioavailability, and health benefits of fatty acid esters of hydroxy fatty acids (FAHFAs), emphasizing their potential as functional foods. Understanding FAHFAs in food can help develop targeted functional foods and explore their role in human health, including antidiabetic and anti‐inflammatory effects ...
Lipsa Rani Nath   +2 more
wiley   +1 more source

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