Results 71 to 80 of about 6,230 (208)

Outcome parameters in studies investigating dry eye disease: A systematic literature review

Acta Ophthalmologica, Volume 104, Issue 4, Page e363-e372, June 2026.
Abstract The development of effective therapeutics for dry eye disease (DED) is challenging due to its complex pathophysiology, heterogeneous patient presentation and the significant failure rate of previous clinical development programs. This underlines the importance of the selection of appropriate endpoints for clinical trials.
Viktoria Pai, Doreen Schmidl, Liudmyla Petric, Patrick Janku, Theresa Lindner, Ulrich Graf, Jacqueline Chua, Leopold Schmetterer, Gerhard Garhöfer   +8 more
wiley   +1 more source

Dry Eye and Meibomian Gland Dysfunction in Neovascular Age-Related Macular Degeneration Patients Treated with Intravitreal Injections

Türk Oftalmoloji Dergisi, 2022
Objectives:To determine if patients treated with multiple intravitreal injections for neovascular age-related macular degeneration are more likely to suffer from dry eye and meibomian gland dysfunction.Materials and Methods:Sixty eyes of 30 patients were
Pelin Kıyat, Melis Palamar, Serhad Nalçacı, Cezmi Akkın   +3 more
doaj   +1 more source

Quantifying Meibomian Gland Morphology Using Artificial Intelligence [PDF]

, 2021
SignificanceQuantifying meibomian gland morphology from meibography images is used for the diagnosis, treatment, and management of meibomian gland dysfunction in clinics.
Jiayun Wang, Yeh, Thao N, Yu, Stella X, Andrew D. Graham, Yeh, Thao N., Li, Shixuan, Shixuan Li, Lin, Meng C., Rudrasis Chakraborty, Thao N. Yeh, Wang, Jiayun, Meng C. Lin, Stella X. Yu, Lin, Meng C, Graham, Andrew D., Yu, Stella X., Graham, Andrew D, Chakraborty, Rudrasis   +17 more
core   +1 more source

Ocular surface disease in atopic dermatitis

Acta Ophthalmologica, Volume 104, Issue S291, Page S4-S28, June 2026.
ENGLISH SUMMARY Atopic keratoconjunctivitis (AKC) is a severe ocular surface disease (OSD) that significantly affects patients' quality of life and can lead to blindness. AKC is associated with atopic dermatitis (AD), a common chronic inflammatory skin disease affecting both children and adults.
Pernille May Hansen
wiley   +1 more source

Effects of radiation therapy on the meibomian glands and dry eye in patients with ocular adnexal mucosa-associated lymphoid tissue lymphoma

BMC Ophthalmology, 2020
Background Radiation therapy (RT) is the treatment of choice in patients with low-grade ocular adenexal mucosa-associated lymphoid tissue lymphoma (OAML) and many of them experience post-RT dry eye with varying severity.
Sung Eun Kim, Hee Jung Yang, Suk-Woo Yang   +2 more
doaj   +1 more source

Pre-processing and grading of Meibomian images.

, 2022
a) original meibogram. Red squares show the positions where an angle of deviation exceeds 45°. Blue squares indicate regions with noticeable narrowing of glands. b) Meibomian image with increased contrast.
Mikolaj Pochylski (11835915), Kamila Ciężar (12936651)   +1 more
core   +1 more source

X‐Linked Anhidrotic Ectodermal Dysplasia in A 19‐Year‐Old Male: A Classic Phenotype

Clinical Case Reports, Volume 14, Issue 5, May 2026.
ABSTRACT X‐linked anhidrotic/hypohidrotic ectodermal dysplasia (XLHED), also known as Christ‐Siemens‐Touraine syndrome, is a rare genetic disorder characterized by the abnormal development of ectodermal structures, primarily affecting sweat glands, hair, and teeth. It results from mutations in the Ectodysplasin A (EDA) gene.
Laxman Chapagain, Anumesh Dahal, Pooja Gupta, Prajwal Pudasaini, Upama Paudel   +4 more
wiley   +1 more source

Morphological and Imaging Characterization of the Eye and Adnexa of the Lesser Anteater (Tamandua tetradactyla)

Anatomia, Histologia, Embryologia, Volume 55, Issue 3, May 2026.
ABSTRACT The southern tamandua (Tamandua tetradactyla) is a species vulnerable to environmental disturbances, largely due to increasing overlap between its natural habitat and anthropogenically modified landscapes. Detailed anatomical knowledge of the eye and orbital structures, supported by imaging and histological analyses, is essential to improve ...
Estela Larissa Silva dos Santos, Amanda Vieira Fernandes, Francisco de Assis Dórea Neto, Caterina Muramoto, Danielle Nascimento Silva, Ana Cláudia Raposo, Marcia Maria Dantas de Faria, Ricardo Diniz Guerra e Silva, Alessandra Estrela Lima, Érica Augusta dos Anjos Cerqueira da Silva, Arianne Pontes Oriá   +10 more
wiley   +1 more source

Congenital aniridia: European COST action ANIRIDIA‐NET guidelines for diagnosis, management and care

Acta Ophthalmologica, Volume 104, Issue 3, Page 267-279, May 2026.
Abstract Congenital aniridia is a rare ocular disorder affecting the majority of eye structures and can be associated with systemic manifestations. The main visible phenotypic characteristic is the partial or complete absence of the iris; however, foveal hypoplasia is a more frequent and reliable clinical sign. Other ocular comorbidities are associated
Davide Romano, Vito Romano, Alejandra Daruich, Giulio Ferrari, Matthieu Robert, Francesco Semeraro, Neil Lagali, Dominique Bremond‐Gignac, the ANIRIDIA‐NET Clinical Guidelines Working Group, Miriam Barbany, Claus Cursiefen, Stefano Ferrari, Francisco Figueiredo, Christina Grupcheva, Jesper Hjortdal, Elke Kreps, Erlend Landsend, Laura Mauring, Hilde Pedersen, Nora Szentmáry, Bogumil Wowra, the Aniridia‐Europa and Geniris Working Group, Sophie Valleix, Juan Álvarez de Toledo, James Lauderdale, Tor Paaske Utheim, Paolo Rama   +26 more
wiley   +1 more source

Novel drugs approved by the EMA, the FDA and the MHRA in 2025: A year in review

British Journal of Pharmacology, Volume 183, Issue 9, Page 1779-1813, May 2026.
Abstract In the 2025 novel drug mini‐review, one can take a full measure of the ingenuity that underlies current drug design and development, despite the year's smaller harvest (46 novel drugs) compared to 2024 (53) and 2023 (70). 54% of the novel drugs are first‐in‐class (FIC).
Andreas Papapetropoulos, Stavros Topouzis, Steve P. H. Alexander, Miriam M. Cortese‐Krott, Zsuzsanna Helyes, Kirill Martemyanov, Claudio Mauro, Nithyanandan Nagercoil, Reynold A. Panettieri Jr, Hemal H. Patel, Rainer Schulz, Barbara Stefanska, Gary J. Stephens, Nathalie Vergnolle, Xin Wang, Stephen Ward, Péter Ferdinandy   +16 more
wiley   +1 more source